WordNet

a conjugated protein linked to a compound of iron and porphyrin (同)haemoprotein
smear with blood, as in a hunting initiation rite, where the face of a person is smeared with the blood of the kill
temperament or disposition; "a person of hot blood"
people viewed as members of a group; "we need more young blood in this organization"
the fluid (red in vertebrates) that is pumped through the body by the heart and contains plasma, blood cells, and platelets; "blood carries oxygen and nutrients to the tissues and carries away waste products"; "the ancients believed that blood was the sea
any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"

PrepTutorEJDIC

『血』,『血』液 / 流血(bloodshed);殺人 / 気質,気性,血気,血潮 / 『血統』,血縁(kinship);生まれ,家柄;《the~》王家の血統 / (人種・出身国の)系 / 〈人〉‘に'初めての経験をさせる / 〈猟犬〉‘に'初めて獲物を血を味わわせる
蛋白(たんばく)質
純血の,純種の / 《複合語を作って》「…の血(性質)を持った」の意を表す

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/04/18 20:47:11」(JST)

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Plasma proteins, also termed serum proteins or blood proteins, are proteins present in blood plasma. They serve many different functions, including transport of lipids, hormones, vitamins and metals in the circulatory system and the regulation of acellular activity and functioning and in the immune system. Other blood proteins act as enzymes, complement components, protease inhibitors or kinin precursors. Contrary to popular belief, hemoglobin is not a blood protein, as it is carried within red blood cells, rather than in the blood serum.

Serum albumin accounts for 55% of blood proteins, and is a major contributor to maintaining the osmotic pressure of plasma to assist in the transport of lipids and steroid hormones. Globulins make up 38% of blood proteins and transport ions, hormones and lipids assisting in immune function. Fibrinogen comprise 7% of blood proteins; conversion of fibrinogen to insoluble fibrin is essential for blood clotting. The remainder of plasma proteins (1%) is made up of regulatory proteins such as enzymes, proenzymes and hormones. All blood proteins are synthesized in liver except for the gamma globulins.

Separating serum proteins by electrophoresis is a valuable diagnostic tool as well as a way to monitor clinical progress. Current research regarding blood plasma proteins is centered on performing proteomics analyses of serum/plasma in the search for biomarkers. These efforts started with two-dimensional gel electrophoresis^[1] efforts in the 1970s and in more recent times this research has been performed using LC-tandem MS^[2]^[3] based proteomics. The normal laboratory value of serum total protein is around 7 g/dL.

Families of blood proteins:-

Blood protein	Normal level	%	Function
Albumins	3.5-5.0 g/dl^{[citation needed]}	55%	maintains colloid osmotic pressure; create oncotic pressure and transport insoluble molecules
Globulins	2.0-2.5 g/dl^{[citation needed]}	38%	participate in immune system
Fibrinogen	0.2-0.45 g/dl^{[citation needed]}	7%	Blood coagulation
Regulatory proteins		<1%^{[citation needed]}	Regulation of gene expression
Clotting factors		<1%^{[citation needed]}	Conversion of fibrinogen into Fibrin

Examples of specific blood proteins:-

Prealbumin (Transthyretin)
Alpha 1 antitrypsin (neutralizes trypsin that has leaked from the digestive system)
Alpha 1 acid glycoprotein
Alpha 1 fetoprotein
alpha2-macroglobulin
Gamma globulins
Beta-2-microglobulin
Haptoglobin
Ceruloplasmin
Complement component 3
Complement component 4
C-reactive protein (CRP)
Lipoproteins (chylomicrons, VLDL, LDL, HDL)
Transferrin
Prothrombin
MBL or MBP

Notes

^ Anderson NL and Anderson NG (1977). "High Resolution Two-Dimensional Electrophoresis of Human Plasma Proteins". Proceeding of the National Academy of Sciences 74 (12): 5421–5425. doi:10.1073/pnas.74.12.5421. PMC 431746. PMID 271964.
^ Adkins JN et al. (2002). "Toward a human blood serum proteome: analysis by multidimensional separation coupled with mass spectrometry". Molecular and Cellular Proteomics 1 (12): 947–955. doi:10.1074/mcp.M200066-MCP200. PMID 12543931.
^ Jacobs JM et al. (2005). "Utilizing human blood plasma for proteomic biomarker discovery". Journal of Proteome Research 4 (4): 1073–1085. doi:10.1021/pr0500657. PMID 16083256.

References

Clinical Chemistry : a laboratory perspective / [edited by] Wendy Arneson, Jean Brickell.

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English Journal

Plasma Proteomics Biomarkers in Alzheimer's Disease: Latest Advances and Challenges.

Perneczky R1, Guo LH.
Methods in molecular biology (Clifton, N.J.).Methods Mol Biol.2016;1303:521-9. doi: 10.1007/978-1-4939-2627-5_32.
The recent paradigm shift towards a more biologically oriented definition of Alzheimer's disease (AD) in clinical settings increases the need for sensitive biomarkers that can be applied in population-based settings. Blood plasma is easily accessible and contains a large number of proteins related t
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Evaluating Chemical CDK Inhibitors as Cell Death Inducers.

Hirai H1, Nakatsuru Y.
Methods in molecular biology (Clifton, N.J.).Methods Mol Biol.2016;1336:167-78. doi: 10.1007/978-1-4939-2926-9_14.
The cell cycle of eukaryotic cells is regulated by a family of protein kinases called cyclin-dependent kinases (Cdks). We have reported the identification and biological characterization of a highly potent, small-molecule pan-Cdk inhibitor, which inhibited Cdk1, 2, 4, 5, 6, and 9 with equal potency
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Use of the U1A Protein to Facilitate Crystallization and Structure Determination of Large RNAs.

Ferré-D'Amaré AR1.
Methods in molecular biology (Clifton, N.J.).Methods Mol Biol.2016;1320:67-76. doi: 10.1007/978-1-4939-2763-0_6.
The preparation of well-ordered crystals of RNAs with complex three-dimensional architecture can be facilitated by engineering a binding site for the spliceosomal protein U1A into a functionally and structurally dispensable stem-loop of the RNA of interest. Once suitable crystals are obtained, the U
PMID 26227038