bivalirudin

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/02/05 16:40:24」(JST)

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英文文献

  • A novel sequential electrostatic-HILIC SPE within a quantitative method for bivalirudin in human plasma by LC-SRM.
  • MacNeill R1, Acharya V1, Patel N1, Parisi G1, Katto K1, Lovich R1.
  • Bioanalysis.Bioanalysis.2016 Nov;8(21):2195-2203. Epub 2016 Sep 28.
  • AIM: This work set out to realize an idea for a novel means of extracting the peptide therapeutic bivalirudin from human plasma in what would be a uniquely selective means of SPE, a mixed-mode protocol involving electrostatic interactions followed by HILIC.RESULTS: Inter and intra-assay relative err
  • PMID 27678052
  • Transradial access mitigates bleeding benefit offered by bivalirudin over heparin in patients undergoing percutaneous coronary intervention: Insights from meta-analysis of randomized and observational studies.
  • Pasala T1, Gajulapalli RD2, Bolen S3, Bajaj NS4, Gandhi S5, Tandar A1, Owan T1, Welt FG6.
  • International journal of cardiology.Int J Cardiol.2016 Oct 15;221:601-8. doi: 10.1016/j.ijcard.2016.07.043. Epub 2016 Jul 5.
  • OBJECTIVE: Recent randomized control trials (RCTs) showed conflicting efficacy and safety between bivalirudin and heparin during percutaneous coronary intervention (PCI). We aimed to perform an updated meta-analysis, including real-world and trial data to examine the factors affecting their risk-ben
  • PMID 27420586
  • Potential mechanism of acute stent thrombosis with bivalirudin following percutaneous coronary intervention in acute coronary syndromes.
  • Laine M1, Frere C2, Cuisset T3, Paganelli F4, Morange PE5, Dignat-George F2, Berbis J6, Camoin-Jau L7, Bonello L8.
  • International journal of cardiology.Int J Cardiol.2016 Oct 1;220:496-500. doi: 10.1016/j.ijcard.2016.06.247. Epub 2016 Jun 28.
  • BACKGROUND: Clinical trials have demonstrated an excess of acute stent thrombosis (AST) in acute coronary syndromes patients (ACS) undergoing percutaneous coronary intervention (PCI) with bivalirudin compared to heparin. We aimed to investigate the potential mechanisms responsible for thrombus forma
  • PMID 27390976

和文文献

  • Pharmacokinetics, Pharmacodynamics, Tolerability and Safety of Single Doses of Bivalirudin in Healthy Chinese Subjects
  • ZHANG Dongmei,WANG Zining,ZHAO Xia [他]
  • Biological & pharmaceutical bulletin 34(12), 1841-1848, 2011-12-00
  • NAID 40019073443
  • Pharmacokinetics, Pharmacodynamics, Tolerability and Safety of Single Doses of Bivalirudin in Healthy Chinese Subjects
  • Zhang Dongmei,Wang Zining,Zhao Xia,Lu Wei,Gu Jingkai,Cui Yimin
  • Biological and Pharmaceutical Bulletin 34(12), 1841-1848, 2011
  • … The objectives of the present study were to assess pharmacokinetics, pharmacodynamics, tolerability and safety of intravenous administration of bivalirudin, a direct thrombin inhibitor, in healthy Chinese subjects. … 48 subjects were equally divided into 4 groups (0.5 mg/kg, 0.75 mg/kg, 1.05 mg/kg intravenous bolus, and 0.75 mg/kg intravenous bolus followed by an infusion of 1.75 mg/kg per hour for 4 h) by a randomized, single-blind and placebo-controlled (bivalirudin groups: n=9/group; …
  • NAID 130001872605
  • Liquid chromatography method for determination of bivalirudin in human plasma and urine using automated ortho-phthalaldehyde derivatization and fluorescence detection
  • FARTHING Don,LARUS Terri,FAKHRY Itaf,GEHR Todd,PRATS Jayne,SICA Domenic
  • Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 802(2), 355-359, 2004-04-05
  • NAID 10016537939

関連リンク

血液・呼吸器内科のお役立ち情報 北陸から良き内科医を、そして世界に通用する血液と呼吸器の専門医を育てる ... 【bivalirudin】 (Hirulog ;ヒルログとも言う) bivalirudin (Hirulog ;ヒルログとも言う)は、20個のアミノ酸からなるヒルジン誘導体 ...
結論 経皮的冠動脈形成術(PCI)を施行かつGP IIb/IIIa受容体拮抗薬(GPI)を投与された中等度-高リスクの急性冠症候群(ACS)患者において,未分画heparinまたはenoxaparinの代わりにbivalirudinを投与しても,臨床アウトカムは同 ...

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