WordNet
- a drug that neutralizes or counteracts the effects of another drug
- a muscle that relaxes while another contracts; "when bending the elbow the triceps are the antagonist"
- a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response
- any of several similar lipophilic amines used as tranquilizers or sedatives or hypnotics or muscle relaxants; chronic use can lead to dependency
PrepTutorEJDIC
- 対立する人,敵対者,競争相手(opponent)
- =sense organ / 受信装置
UpToDate Contents
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- 1. ベンゾジアゼピンの中毒および離脱 benzodiazepine poisoning and withdrawal
- 2. 消化管内視鏡検査に対する鎮静の合併症 complications of procedural sedation for gastrointestinal endoscopy
- 3. 成人における肝性脳症：治療 hepatic encephalopathy in adults treatment
- 4. 肝性脳症：病因 hepatic encephalopathy pathogenesis
- 5. 小児に対する手術室外での鎮静処置に使用する薬剤 pharmacologic agents for pediatric procedural sedation outside of the operating room
English Journal
- Anticonvulsant Effects of Fuzi Total Alkaloid on Pentylenetetrazole-Induced Seizure in Mice.
- Li B, Tang F, Wang L, Liu L, Zhao J, Zhou Y, Wang Y, Song Y, Li Y, Cui R.SourceNational Engineering Laboratory for Druggable Gene and Protein Screening, Northeast Normal University, China.
- Journal of pharmacological sciences.J Pharmacol Sci.2013 Oct 4. [Epub ahead of print]
- We investigated the anticonvulsant effect of acute Fuzi total alkaloid (FTA) in seizure induced by the GABAA-receptor antagonist pentylenetetrazole (PTZ). FTA significantly increased the seizure latency and decreased the mortality in PTZ-treated mice. Administration of PTZ increased c-Fos expression
- PMID 24096829
- N-methyl-D-aspartate receptors and protein synthesis are necessary for reinstatement of conditioned fear.
- Shen H, Igarashi H, Imamura N, Matsuki N, Nomura H.SourceLaboratory of Chemical Pharmacology, Graduate School of Pharmaceutical Science, University of Tokyo, Tokyo, Japan.
- Neuroreport.Neuroreport.2013 Oct 2;24(14):763-7. doi: 10.1097/WNR.0b013e328363b36c.
- Conditioned fear is extinguished if a conditioned animal receives the conditioned stimulus without an unconditioned stimulus. The extinguished fear response can be reinstated after the animal experiences a mild unconditioned stimulus. Although extensive studies on the neuronal circuitry and neuroche
- PMID 23820739
- The involvement of magnoflorine in the sedative and anxiolytic effects of Sinomeni Caulis et Rhizoma in mice.
- de la Peña JB, Lee HL, Yoon SY, Kim GH, Lee YS, Cheong JH.SourceUimyung Research Institute for Neuroscience, Department of Pharmacy, Sahmyook University, 26-21 Kongneung-dong, Nowon-gu, Seoul, 139-742, Republic of Korea.
- Journal of natural medicines.J Nat Med.2013 Oct;67(4):814-21. doi: 10.1007/s11418-013-0754-3. Epub 2013 Mar 3.
- The present study seeks to evaluate the sedative and anxiolytic effects of the 70 % ethanol extract of Sinomeni Caulis et Rhizoma (SR). The extract was orally administered to mice at dosages of 25, 50, 100, 200 or 400 mg/kg. The mice were then subjected to an array of behavioral tests to assess th
- PMID 23456265
Japanese Journal
- フルマゼニル (特集 拮抗作用から見た麻酔関連薬物の最新知見)
- 水野 樹
- 麻酔 62(1), 10-18, 2013-01
- NAID 40019551537
- The ethanol extract of Cirsium japonicum increased chloride ion influx through stimulating GABAA receptor in human neuroblastoma cells and exhibited anxiolytic-like effects in mice
- , , , , , ,
- Drug Discoveries & Therapeutics 7(1), 18-23, 2013
- … This anxiolytic effects of the extract were comparable to that of the benzodiazepine, diazepam. … The CJ extract dose-dependently increased chloride ion (Cl‒) influx, which was blocked by co-administration of the GABAA receptor competitive antagonist, bicuculline, suggesting a GABAA receptor – Cl‒ channel mechanism of action. …
- NAID 130005054756
- Anticonvulsant Effects of Fuzi Total Alkaloid on Pentylenetetrazole-Induced Seizure in Mice
- , , [他], , , , , , ,
- Journal of Pharmacological Sciences 123(2), 195-198, 2013
- … We investigated the anticonvulsant effect of acute Fuzi total alkaloid (FTA) in seizure induced by the GABAA-receptor antagonist pentylenetetrazole (PTZ). … Furthermore, the effects of FTA on PTZ-induced seizure and c-Fos expression were reversed by the GABAA/benzodiazepine receptor–selective antagonist flumazenil. …
- NAID 130003382589
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- Disorders Drugs People Directories Terms Movies Blog benzodiazepine receptor antagonist is a kind of action Molecular entities Share this with Google Plus One Linkedin Share Button Tweet Widget Facebook Like Opinion 03/20 ...
- The receptor to which benzodiazepine hypnosedatives and anticonvulsants bind was discovered and characterized in the late 1970s. Agonists and inverse agonists that act at various sites within the receptor complex have been ...
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★リンクテーブル★
| リンク元 | 「ベンゾジアゼピン受容体拮抗剤」「ベンゾジアゼピン受容体拮抗薬」 |
| 関連記事 | 「benzodiazepine receptor」「benzodiazepine」「benzodiazepines」 |
「ベンゾジアゼピン受容体拮抗剤」
「ベンゾジアゼピン受容体拮抗薬」
「benzodiazepine receptor」
- 関
- GABA-A receptor