barbiturates

出典: meddic

バルビツール酸系

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/08/04 14:31:02」(JST)

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英文文献

  • Immunological GABAergic interactions and therapeutic applications in autoimmune diseases.
  • Prud'homme GJ1, Glinka Y2, Wang Q3.
  • Autoimmunity reviews.Autoimmun Rev.2015 Nov;14(11):1048-56. doi: 10.1016/j.autrev.2015.07.011. Epub 2015 Jul 29.
  • Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the brain. However, it is also produced in other sites; notably by pancreatic β cells and immune cells. The function of GABA in the immune system is at an early stage of study, but it exerts inhibitory effects that are relev
  • PMID 26226414
  • Super-Refractory Status Epilepticus.
  • Cuero MR1, Varelas PN2,3.
  • Current neurology and neuroscience reports.Curr Neurol Neurosci Rep.2015 Nov;15(11):74. doi: 10.1007/s11910-015-0594-5.
  • Although the vast majority of patients with status epilepticus (SE) respond fairly well to the first- or second-line anti-epileptics, a minority require anesthetic agents to put the seizures under control. An even smaller number of patients do not even respond to those and constitute the subgroup of
  • PMID 26404727
  • Management of Intracranial Pressure.
  • Freeman WD.
  • Continuum (Minneapolis, Minn.).Continuum (Minneap Minn).2015 Oct;21(5 Neurocritical Care):1299-323. doi: 10.1212/CON.0000000000000235.
  • PURPOSE OF REVIEW: Intracranial pressure (ICP) can be elevated in traumatic brain injury, large artery acute ischemic stroke, intracranial hemorrhage, intracranial neoplasms, and diffuse cerebral disorders such as meningitis, encephalitis, and acute hepatic failure. Raised ICP is also known as intra
  • PMID 26426232

和文文献

  • Preparation of Magnetic Molecularly Imprinted Polymer for Cyclobarbital and Its Application to the Assay of Phenobarbital in Human Serum
  • , ,
  • CHROMATOGRAPHY advpub(0), 2015
  • A magnetic molecularly imprinted polymer (M-MIP) for cyclobarbital (CY) has been prepared by a multi-step swelling and polymerization method using a uniformly-sized magnetic particle as the shape temp …
  • NAID 130005070517
  • In-line Solid-phase Extraction–Capillary Zone Electrophoresis for the Determination of Barbiturate Drugs in Human Urine
  • BOTELLO Igor,BORRULL Francesc,AGUILAR Carme [他]
  • Analytical Sciences 30(10), 971-977, 2014-10
  • NAID 40020224626
  • In-line Solid-phase Extraction–Capillary Zone Electrophoresis for the Determination of Barbiturate Drugs in Human Urine
  • , , ,
  • Analytical Sciences 30(10), 971-977, 2014
  • … This method provides a reproducible and sensitive analysis of urine samples in the determination of barbiturates drugs. …
  • NAID 130004694056

関連リンク

barbiturates are a type of depressant drug that cause relaxation and sleepiness. Generally, a doctor prescribes a lethal dose of barbiturates, but is not legally allowed to administer it. British Dictionary definitions for barbiturates / ...
Barbiturates Definition Barbiturates are medicines that act on the central nervous system and cause drowsiness and can control seizures. Purpose Barbiturates are in the group of medicines known as central nervous system ...

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★リンクテーブル★
先読みバルビツール酸系
リンク元薬物濫用」「バルビツール酸系催眠薬
関連記事barbiturate

バルビツール酸系」

  [★]

バルビツール酸誘導体 barbiturate derivative、バルビツレート barbiturateバルビツール酸塩バルビタール系薬剤バルビツール酸系化合物バルビツール酸誘導体
バルビツール酸チオバルビツレート

作用機序

イオンチャネル型。5量体。開口によりCl-が流入→電位依存性Ca2+の開口抑制など
ベンゾジアゼピン系薬物、バルビツール酸系薬物、エタノールが作用

適応

  • 静脈麻酔、抗痙攣薬、脳保護薬
  • 抗てんかん薬としての適応

禁忌

  • 気管支喘息。血尿症。ローンホル

副作用

  • 薬物依存性が高い
  • REM睡眠が短縮しやすい
  • 過量により急性中毒

バルビツール酸系薬物

  • Pentobarbital 短い。麻酔前投与
  • Amobarbital
  • Phenobarbital 長い。抗てんかん薬。睡眠薬としては適さない




薬物濫用」

  [★]

drug abuse, substance abuse
薬物乱用
薬物依存、薬物嗜癖、物質乱用物質依存症薬物使用接着剤吸引


薬物使用が身体に及ぼす効果

  • 濫用 substance abuse:a pattern of abnormal substance use that leads to impairment of occupational, physical, or social functioning(BBS.73)
  • 依存 substance dependence:ub stance abuse puls withdrawal symptoms, tolerance, or a pattern of repetitive use(BBS.73)
  • 離脱 withdrawal:the development of physical or pschological symptoms after the reduction or cessation of intake of a substance(BBS.73)
  • 耐性 tolerance:the need for increased amounts of the substance to achieve the same positive psychological effect(BBS.73)
  • 交差耐性 cross-tolerance:the development of tolerance to one substance as the result of using another substance(BBS.73)

薬物

  • コカイン cocaine crack freebase 精神依存有り。身体依存無し 精神依存生じやすい。耐性発現殆ど無し コカ

精神依存、身体依存

  精神依存 身体依存
コカイン、アンフェタミン類(アンフェタミン、メチルフェタミン)、大麻  
麻薬(モルヒネヘロインコデイン)、バルビツール酸系(フェノバルビタールチオペンタール)、アルコール



バルビツール酸系催眠薬」

  [★]

barbiturates
習慣性医薬品


barbiturate」

  [★] バルビツール酸バルビツール酸系

WordNet   license wordnet

「organic compound having powerful soporific effect; overdose can be fatal」

PrepTutorEJDIC   license prepejdic

「バルビツル酸塩(睡眠薬・鎮通剤用)」




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