English Journal

Building models for postmortem abnormalities in hippocampus of schizophrenics.

Benes FM1.
Schizophrenia research.Schizophr Res.2015 Mar 3. pii: S0920-9964(15)00018-3. doi: 10.1016/j.schres.2015.01.014. [Epub ahead of print]
Postmortem studies have suggested that there is abnormal GABAergic activity in the hippocampus in schizophrenia (SZ). In micro-dissected human hippocampal slices, a loss of interneurons and a compensatory upregulation of GABAA receptor binding activity on interneurons, but not PNs, has suggested tha
PMID 25749020

Intracellular bicarbonate regulates action potential generation via KCNQ channel modulation.

Jones RT1, Faas GC, Mody I.
The Journal of neuroscience : the official journal of the Society for Neuroscience.J Neurosci.2014 Mar 19;34(12):4409-17. doi: 10.1523/JNEUROSCI.3836-13.2014.
Bicarbonate (HCO3(-)) is an abundant anion that regulates extracellular and intracellular pH. Here, we use patch-clamp techniques to assess regulation of hippocampal CA3 pyramidal cell excitability by HCO3(-) in acute brain slices from C57BL/6 mice. We found that increasing HCO3(-) levels enhances a
PMID 24647960

Neuronal Ig/Caspr recognition promotes the formation of axoaxonic synapses in mouse spinal cord.

Ashrafi S1, Betley JN2, Comer JD3, Brenner-Morton S2, Bar V4, Shimoda Y5, Watanabe K6, Peles E4, Jessell TM7, Kaltschmidt JA8.
Neuron.Neuron.2014 Jan 8;81(1):120-9. doi: 10.1016/j.neuron.2013.10.060.
Inhibitory microcircuits are wired with a precision that underlies their complex regulatory roles in neural information processing. In the spinal cord, one specialized class of GABAergic interneurons (GABApre) mediates presynaptic inhibitory control of sensory-motor synapses. The synaptic targeting
PMID 24411736

Japanese Journal

Glutamate decarboxylase-immunoreactive terminals of Golgi-impregnated axoaxonic cells and of presumed basket cells in synaptic contact with pyramidal neurons of the cat's visual cortex

FREUND T. F.
J. Comp. Neurol. 221(3), 263-278, 1983
NAID 30002197581

Axoaxonic contacts in the cuneate nucleus, probable basis for presynaptic depolarization.

WALBERG F.
Exp. Neurol. 13, 218-231, 1965
NAID 30020350334

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Axoaxonic | definition of axoaxonic by Medical dictionary

axoaxonic [ak″so-ak-son´ik] referring to a synapse between the axon of one neuron and the axon of another. ax·o·ax·on·ic (ak'sō-ak-son'ik), Relating to synaptic contact between the axon of one nerve cell and that of another. See: synapse