出典: meddic

  • the total binding strength of a molecule with more than one binding site is called its avidity (IMM.740)
  • 機能的親和力。例えば、5量体IgMと抗原との間の平衡定数が大きいとき、アビディティーが大きいという。

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2012/08/27 15:33:44」(JST)

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  • Rapidly Growing Complex Fibroadenoma With Surrounding Ductal Hyperplasia Mimics Breast Malignancy on Serial F-18 FDG PET/CT Imaging.
  • Makis W, Ciarallo A, Hickeson M, Derbekyan V.SourceFrom the *Department of Nuclear Medicine, Brandon Regional Health Centre, Brandon, Canada; and †Department of Nuclear Medicine, Royal Victoria Hospital, McGill University Health Centre, Montreal, Quebec, Canada.
  • Clinical nuclear medicine.Clin Nucl Med.2011 Jul;36(7):576-9.
  • A 30-year-old woman was referred for an F-18 fluorodeoxyglucose (FDG) PET/CT to rule out lymphoma, and was found to have an incidental FDG-avid right breast nodule that grew significantly in size and FDG uptake on a subsequent scan, raising suspicion of a growing breast malignancy. Histologic evalua
  • PMID 21637064
  • F-18 FDG PET/CT as a Crucial Guide Toward Optimal Treatment Planning in a Case of Postirradiation Sarcoma 10 Years After Primary Bone Lymphoma of the Pelvis.
  • de Rooy JW, Hambrock T, Vriens D, Flucke UE, van der Geest IC, van de Luijtgaarden AC, Schreuder BW, de Geus-Oei LF.SourceFrom the Departments of *Radiology, †Nuclear Medicine, ‡Pathology, §Orthopedic Surgery, and ¶Medical Oncology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
  • Clinical nuclear medicine.Clin Nucl Med.2011 Jul;36(7):565-7.
  • Ten years after chemoradiation for primary lymphoma of the left pelvic bone, a 38-year-old man presented with a 4-month history of gradually increasing pain in his left upper leg and thigh. Initial radiographs and contrast-enhanced magnetic resonance imaging were consistent with recurrent lymphoma,
  • PMID 21637060


  • Protein-based Open Sandwich Immuno-PCR for Sensitive Detection of Small Biomarkers
  • HASAN Sharif,DONG Jinhua,HARA Yuko [他]
  • Analytical Sciences 29(9), 871-876, 2013-09
  • NAID 40019779868
  • The long-term immunosuppressive effects of disulfide-linked HLA-G dimer in mice with collagen-induced arthritis
  • Kuroki Kimiko,Hirose Kaoru,Okabe Yuki,Fukunaga Yuko,Takahashi Ami,Shiroishi Mitsunori,Kajikawa Mizuho,Tabata Shigekazu,Nakamura Seiko,Takai Toshiyuki,Koyanagi Satoru,Ohdo Shigehiro,Maenaka Katsumi
  • HUMAN IMMUNOLOGY 74(4), 433-438, 2013-04
  • … In accordance with this result, a binding study revealed that the HLA-G dimer binds PIR-B, the mouse homolog of the LILRBs, with higher affinity and avidity than the monomer. …
  • NAID 120005297913
  • P3-15-7 母体血サイトメガロウイルスIgG avidity測定による先天性感染の発生予知(Group 120 周産期・感染症,一般演題,公益社団法人日本産科婦人科学会第65回学術講演会)
  • 森上 聡子,蝦名 康彦,平久 進也,谷村 憲司,森岡 一朗,園山 綾子,峰松 俊夫,山田 秀人
  • 日本産科婦人科學會雜誌 65(2), 897, 2013-02-01
  • NAID 110009639431


Avidity develops and sells molecular affinity tools for connecting molecules. Our patented AviTag? technology employs a highly targeted enzymatic conjugation of a single biotin on a unique 15 amino acid peptide tag using the biotin ...


rx-2.jpg (21212 bytes)AvidityEndocytosis, Dynamin, Dynamic dynamin AvidityReactions:avidity

リンク元affinity」「結合力」「結合活性」「アビディティー」「associative strength
拡張検索avidity index」「gravidity」「antibody avidity



  • 固有親和力
  • 例えば、抗体の一方の抗原結合部位とB細胞エピトープとの間の平衡定数で表されるような親和性を指す

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「a natural attraction or feeling of kinship; "an affinity for politics"; "the mysterious affinity between them"; "James''s affinity with Sam"」

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「inherent resemblance between persons or things」

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「the force attracting atoms to each other and binding them together in a molecule; "basic dyes have an affinity for wool and silk"」
chemical attraction

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「a close connection marked by community of interests or similarity in nature or character; "found a natural affinity with the immigrants"; "felt a deep kinship with the other students"; "anthropology''s kinship with the humanities"」

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「(biology) state of relationship between organisms or groups of organisms resulting in resemblance in structure or structural parts; "in anatomical structure prehistoric man shows close affinity with modern humans"」
phylogenetic relation

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「(anthropology) kinship by marriage or adoption; not a blood relationship」

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「(immunology) the attraction between an antigen and an antibody」

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「〈C〉(人・物に対する)好み,親近感《+『for』(『to, with』)+『名』》 / 〈U〉〈C〉(2者の間の)密接な関係,類似《+『between』+『名』》;(…との)類縁《+『with』+『名』》 / 〈U〉〈C〉親和力(原子が化学反応を起こしやすい力)」



avidityassociative strength, binding force







associative strength」



avidity index」


  • ELISAによる抗体の定量する際に用いられる指標
  • 一次抗体(検体)を結合させた後、8M尿素処理により低いavidityの抗体を抗体から離脱させ、二次抗体の反応量を検出
  • 8M尿素処理しないものとの反応量の比をとり、avidity indexとする。
  • ウイルスの初感染ではavidity indexが低いはずである。
  • 鑑別に用いられるウイルス:風疹ウイルス、サイトメガロウイルス、水痘ウイルス、トキソプラズマ



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「technical terms for pregnancy」
gravidness, gravidation

antibody avidity」


antibody affinity

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