UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. 心血管疾患の二次予防 secondary prevention of cardiovascular disease
2. 心電図チュートリアル：心筋梗塞 ecg tutorial myocardial infarction
3. 不安定狭心症または非ST上昇型心筋梗塞後の有害転帰の危険因子 risk factors for adverse outcomes after unstable angina or non st elevation myocardial infarction
4. 急性心筋梗塞を合併する心原性ショックの予後および治療 prognosis and treatment of cardiogenic shock complicating acute myocardial infarction
5. 鎌状赤血球症を伴う成人における急性胸部症候群 acute chest syndrome in adults with sickle cell disease

English Journal

Significance of plasma adiponectin for diagnosis, neurological severity and functional outcome in ischemic stroke - Research for Biomarkers in Ischemic Stroke (REBIOS).

Kuwashiro T1, Ago T2, Kamouchi M3, Matsuo R3, Hata J4, Kuroda J3, Fukuda K5, Sugimori H3, Fukuhara M6, Awano H7, Isomura T7, Suzuki K7, Yasaka M8, Okada Y8, Kiyohara Y6, Kitazono T3.
Metabolism: clinical and experimental.Metabolism.2014 Sep;63(9):1093-103. doi: 10.1016/j.metabol.2014.04.012. Epub 2014 May 2.
OBJECTIVE: Although adiponectin is a major adipocytokine that affects the pathogenesis of various cardiovascular diseases, its clinical significance in stroke remains controversial. We investigated the clinical significance of plasma adiponectin for the diagnosis, neurological severity and functiona
PMID 24929894

Rognoni A, Cavallino C, Lupi A, Secco GG, Veia A, Bacchini S, Rosso R, Bunelleschi S, Rametta F, Bongo AS1.
Recent patents on cardiovascular drug discovery.Recent Pat Cardiovasc Drug Discov.2014 Sep 1. [Epub ahead of print]
Cardiovascular disease and in particular acute coronary syndromes are one of principle causes of death in the industrialized countries. In the setting of acute coronary syndromes (both ST - segment or non ST - segment elevation myocardial infarction), platelets aggregation play a key and central rol
PMID 25174338

Inhibition of ADP-induced platelet aggregation and involvement of non-cellular blood chemical mediators are responsible for the antithrombotic potential of the fruits of Lagenaria siceraria.

Rajput MS1, Balekar N2, Jain DK2.
Chinese journal of natural medicines.Chin J Nat Med.2014 Aug;12(8):599-606. doi: 10.1016/S1875-5364(14)60091-1.
AIM: The fruits of Lagenaria siceraria (Molina) Standl. (Cucurbitaceae), a commonly used vegetable, are reported to possess various medicinal properties. In previous studies, the fibrinolytic potential of an ethanolic extract of fruits of Lagenaria siceraria was investigated in comparison with kaemp
PMID 25156285

ISHIBASHI AKIRA,YOSHITAKE YOSINORI,ADACHI HISASHI
The Kurume Medical Journal, 2013
… Subtypes of strokes were lacunar infarction (LI) in 188 (30.0%), atherothrombotic infarction (ATCI) in 268 (42.0%), and cardioembolic infarction (CEI) in 169 (27.0%). … In a univariate analysis, the administration of edaravone did not have a significant effect on total death from all types of cerebral infarction. …
NAID 130003384365

Thromboxane A2 Generation, in the Absence of Platelet COX-1 Activity, in Patients With and Without Atherothrombotic Myocardial Infarction

DeFilippis Andrew P.,Oloyede Oluwasegun S.,Andrikopoulou Efstathia,Saenger Amy K.,Palachuvattil Joel M.,Fasoro Yetunde A.,Guallar Eliseo,Blumenthal Roger S.,Kickler Thomas S.,Jaffe Allan S.,Gerstenblith Gary,Schulman Steven P.,Rade Jeffrey J.
Circulation Journal 77(11), 2786-2792, 2013
… The aim of this study was to evaluate TxA2 production, in the absence of platelet COX-1 activity, in coronary atherosclerotic heart disease patients with and without atherothrombotic myocardial infarction (MI). … Median urine 11-dehydro-TxB2 was no different in those with and without a diagnosis of atherothrombotic MI (325 vs. 311pg/mg creatinine, P=0.59 via polyclonal ELISA) and (312 vs. 244pg/mg creatinine, P=0.11 via LC-MS/MS). …
NAID 130003361848

Management and Two-Year Long-Term Clinical Outcome of Acute Coronary Syndrome in Japan:– Prevention of AtherothrombotiC Incidents Following Ischemic Coronary Attack (PACIFIC) Registry –

Daida Hiroyuki,Miyauchi Katsumi,Ogawa Hisao,Yokoi Hiroyoshi,Matsumoto Masayasu,Kitakaze Masafumi,Kimura Takeshi,Matsubara Tetsuo,Ikari Yuji,Kimura Kazuo,Tsukahara Kengo,Origasa Hideki,Morino Yoshihiro,Tsutsui Hiroyuki,Kobayashi Masayuki,Isshiki Takaaki
Circulation Journal 77(4), 934-943, 2013
… Background: Japanese patients have been at low risk for cardiovascular events compared with Western countries, but the data regarding current treatment status and rate of subsequent atherothrombotic events after acute coronary syndrome (ACS) are limited in Japanese patients. … Methods and Results: The Prevention of AtherothrombotiC Incidents Following Ischemic Coronary attack (PACIFIC) registry is a multicenter, prospective observational study of Japanese ACS patients. …
NAID 130003361601