English Journal
- Acetate supplementation as a means of inducing glioblastoma stem-like cell growth arrest.
- Long PM1, Tighe SW, Driscoll HE, Fortner KA, Viapiano MS, Jaworski DM.
- Journal of cellular physiology.J Cell Physiol.2015 Aug;230(8):1929-43. doi: 10.1002/jcp.24927.
- Glioblastoma (GBM), the most common primary adult malignant brain tumor, is associated with a poor prognosis due, in part, to tumor recurrence mediated by chemotherapy and radiation resistant glioma stem-like cells (GSCs). The metabolic and epigenetic state of GSCs differs from their non-GSC counter
- PMID 25573156
- Behavioural changes observed in demyelination model shares similarities with white matter abnormalities in humans.
- Serra-de-Oliveira N1, Boilesen SN2, Prado de França Carvalho C2, LeSueur-Maluf L2, Zollner Rde L3, Spadari RC2, Medalha CC2, Monteiro de Castro G4.
- Behavioural brain research.Behav Brain Res.2015 Jul 1;287:265-75. doi: 10.1016/j.bbr.2015.03.038. Epub 2015 Apr 2.
- Multiple sclerosis (MS) is a chronic, inflammatory, demyelinating disease of the central nervous system (CNS). Further to the symptoms resulting from demyelination, new studies point to the involvement of neuroinflammation and white matter abnormalities in psychiatric disorders and neurodegenerative
- PMID 25843560
- Heme oxygenase-1 modulates microRNA expression in cultured astroglia: Implications for chronic brain disorders.
- Lin SH1, Song W, Cressatti M, Zukor H, Wang E, Schipper HM.
- Glia.Glia.2015 Jul;63(7):1270-84. doi: 10.1002/glia.22823. Epub 2015 Mar 25.
- BACKGROUND: Over-expression of the heme-degrading enzyme, heme oxygenase-1 (HO-1) promotes iron deposition, mitochondrial damage, and autophagy in astrocytes and enhances the vulnerability of nearby neuronal constituents to oxidative injury. These neuropathological features and aberrant brain microR
- PMID 25820186
Related Links
- Heterogeneity of astroglia Astrocytes (literally ‘star-like cells’) are the most numerous and diverse neuroglial cells in the CNS. While most neuroscientists think they know what an astrocyte is, there is no uniform and unequivocal ...
- Anatomical organization Astrocytes tile the entire CNS in a contiguous and essentially non-overlapping manner that is orderly and well organized (Fig. 3 a). There are no CNS regions devoid of astrocytes or closely related ...
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