aspirin-induced bronchoconstriction

アスピリン誘発性気管支攣縮

WordNet

1. reason or establish by induction
2. cause to arise; "induce a crisis" (同)bring_on
3. produce electric current by electrostatic or magnetic processes (同)induct
4. cause to do; cause to act in a specified manner; "The ads induced me to buy a VCR"; "My children finally got me to buy a computer"; "My wife made me buy a new sofa" (同)stimulate, cause, have, get, make
5. cause to occur rapidly; "the infection precipitated a high fever and allergic reactions" (同)stimulate, rush, hasten
6. the acetylated derivative of salicylic acid; used as an analgesic anti-inflammatory drug (trade names Bayer, Empirin, and St. Joseph) usually taken in tablet form; used as an antipyretic; slows clotting of the blood by poisoning platelets (同)acetylsalicylic_acid, Bayer, Empirin, St. Joseph
7. brought about or caused; not spontaneous; "a case of steroid-induced weakness"

PrepTutorEJDIC

1. 〈人〉‘に'『勧めて』(…)『させる』 / …‘を'『引き起こす』,もたらす(cause) / 〈電気〉‘を'誘導する / …‘を'帰納する
2. 〈U〉アスピリン(鎮痛・解熱剤) / 〈C〉アスピリン錠

UpToDate Contents

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• 1. Aspirin-exacerbated respiratory disease
• 2. 非ステロイド性抗炎症剤（NSAIDs）（アスピリンを含む）：アレルギー反応および偽アレルギー反応 nsaids including aspirin allergic and pseudoallergic reactions
• 3. アスピリン悪化呼吸器疾患（AERD；アスピリン喘息）：非ステロイド性抗炎症剤（NSAIDs）負荷および脱感作 aspirin exacerbated respiratory disease nsaid challenge and desensitization
• 4. 運動誘発性アナフィラキシー：臨床症状、疫学、病因および診断 exercise induced anaphylaxis clinical manifestations epidemiology pathogenesis and diagnosis
• 5. 非ステロイド性抗炎症剤（NSAIDs）反応に対する診断上の課題および脱感作計画 diagnostic challenge and desensitization protocols for nsaid reactions

English Journal

• Aspirin-Exacerbated Respiratory Disease Involves a Cysteinyl Leukotriene-Driven IL-33-Mediated Mast Cell Activation Pathway.

• Liu T1, Kanaoka Y1, Barrett NA1, Feng C2, Garofalo D2, Lai J2, Buchheit K1, Bhattacharya N3, Laidlaw TM1, Katz HR1, Boyce JA4.
• Journal of immunology (Baltimore, Md. : 1950).J Immunol.2015 Oct 15;195(8):3537-45. doi: 10.4049/jimmunol.1500905. Epub 2015 Sep 4.
• Aspirin-exacerbated respiratory disease (AERD), a severe eosinophilic inflammatory disorder of the airways, involves overproduction of cysteinyl leukotrienes (cysLTs), activation of airway mast cells (MCs), and bronchoconstriction in response to nonselective cyclooxygenase inhibitors that deplete ho
• PMID 26342029

• Induced sputum eicosanoids during aspirin bronchial challenge of asthmatic patients with aspirin hypersensitivity.

• Mastalerz L1, Celejewska-Wójcik N, Wójcik K, Gielicz A, Januszek R, Cholewa A, Stręk P, Sanak M.
• Allergy.Allergy.2014 Nov;69(11):1550-9. doi: 10.1111/all.12512. Epub 2014 Sep 12.
• BACKGROUND: Altered metabolism of eicosanoids is a characteristic finding in aspirin-exacerbated respiratory disease (AERD). Bronchial challenge with lysyl-aspirin can be used as a confirmatory diagnostic test for this clinical condition. Induced sputum allows to measure mediators of asthmatic infla
• PMID 25123806

• Prostaglandin E2 deficiency causes a phenotype of aspirin sensitivity that depends on platelets and cysteinyl leukotrienes.

• Liu T1, Laidlaw TM, Katz HR, Boyce JA.
• Proceedings of the National Academy of Sciences of the United States of America.Proc Natl Acad Sci U S A.2013 Oct 15;110(42):16987-92. doi: 10.1073/pnas.1313185110. Epub 2013 Oct 1.
• Aspirin-exacerbated respiratory disease (AERD) is characterized by asthma, tissue eosinophilia, overproduction of cysteinyl leukotrienes (cysLTs), and respiratory reactions to nonselective cyclooxygenase (COX) inhibitors. Ex vivo studies suggest that functional abnormalities of the COX-2/microsomal
• PMID 24085850

Japanese Journal

• Aspirin-induced urticaria and angioedema, but not bronchoconstriction, associated with cysteinyl leukotriene overproduction in 2 patients with asthma

• HIGASHI N
• J Allergy Clin Immunol 110, 666-667, 2002
• NAID 30037709771

• Effect of acyclovir on bronchoconstriction and urinary leukotiene E_4 excretion in aspirin-induced asthma

• YOSHIDA S.
• J Allergy Clin Immunol 102, 909-914, 1998
• NAID 30016513868

• アスピリン喘息における誘発試験の研究 : 吸入負荷を中心にして

• 佐賀 務,末次 勧
• アレルギー 26(2), 85-92, 106, 1977-02-28
• 7例のアスピリン喘息患者に, アスピリン吸入, スルピリン吸入, スルピリン静注の3種の負荷試験を行い, 1秒量と全身症状の変化を観察した.スルピリンの吸入負荷は, 全例静注負荷量より明らかに少量で, 選択的に気管支の反応を誘発した.反応のピークは30分で, 反応閾値は症例により 3-50mg/ml と差があった.上記3種の負荷試験の閾値相互の間, および気管支喘息重症度との間には有意の相関があっ …
• NAID 110002429279

Related Links

• Inhibition of aspirin-induced bronchoconstriction by sodium ...

Bronchial and intravenous provocation tests with indomethacin in aspirin-sensitive asthmatics. Am Rev Respir Dis. 1979 Nov; 120(5):1073-9. [Am Rev Respir Dis. 1979] Neutrophil chemotactic factor of anaphylaxis (NCF-A) release in ...

• Aspirin, salicylate, sulfite and tartrazine induced ...

Aspirin, salicylate, sulfite and tartrazine induced bronchoconstriction. Safe doses and case definition in epidemiological studies Elizabeth H. Corder, C.Edward Buckley III Departments of Medicine, and Immunology, Duke University ...

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★リンクテーブル★

リンク元	「アスピリン誘発性気管支攣縮」
関連記事	「induce」「induced」「bronchoconstriction」

「アスピリン誘発性気管支攣縮」

　　[★]

英

aspirin-induced bronchoconstriction

「induce」

　　[★]

• v.

• 誘発する、誘導する、誘起する、導入する、引き起こす

関

cause、challenge、derivation、elicit、elicitation、evocation、evoke、guidance、induction、inductive、introduce、introduction、precipitate、provocation、provoke、spark

　 　 　 　 　 　

「induced」

　　[★]

• v.

• (induceの過去分詞)誘導される、引き起こされる

hypercalcaemia induced pancreatitis 高カルシウム血症による膵炎

　

「bronchoconstriction」

　　[★]

• 気管支収縮

関

Asthma