aspartate-semialdehyde dehydrogenase

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/07/18 00:50:49」(JST)

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  • Accumulation of a threonine biosynthetic intermediate attenuates general amino acid control by accelerating degradation of Gcn4 via Pho85 and Cdk8.
  • Rawal Y, Qiu H, Hinnebusch AG.
  • PLoS genetics.PLoS Genet.2014 Jul 31;10(7):e1004534. doi: 10.1371/journal.pgen.1004534. eCollection 2014.
  • Gcn4 is a master transcriptional regulator of amino acid and vitamin biosynthetic enzymes subject to the general amino acid control (GAAC), whose expression is upregulated in response to amino acid starvation in Saccharomyces cerevisiae. We found that accumulation of the threonine pathway intermedia
  • PMID 25079372
  • Shape-based virtual screening, docking, and molecular dynamics simulations to identify Mtb-ASADH inhibitors.
  • Kumar R1, Garg P, Bharatam PV.
  • Journal of biomolecular structure & dynamics.J Biomol Struct Dyn.2014 Jun 23:1-12. [Epub ahead of print]
  • Aspartate β-semialdehyde dehydrogenase (ASADH) is a key enzyme for the biosynthesis of essential amino acids and several important metabolites in microbes. Inhibition of ASADH enzyme is a promising drug target strategy against Mycobacterium tuberculosis (Mtb). In this work, in silico approach was u
  • PMID 24875451
  • Evaluation of efficacy, biodistribution and safety of antibiotic-free plasmid encoding somatostatin genes delivered by attenuated Salmonella enterica serovar Choleraesuis.
  • Liang A1, Riaz H1, Dong F1, Luo X1, Yu X1, Han Y1, Chong Z1, Han L2, Guo A2, Yang L3.
  • Vaccine.Vaccine.2014 Mar 10;32(12):1368-74. doi: 10.1016/j.vaccine.2014.01.026. Epub 2014 Jan 30.
  • We describe here a balanced-lethal system using an Asd(+) expression plasmid pVGS/2SS-asd encoding two copies of somatostatin (SS) genes carried by Δasd/Δcrp double mutant Salmonella enterica serovar Choleraesuis (named C501). The advantage of this novel system is the use of asd (aspartate-semiald
  • PMID 24486312


  • Isolation and characterization of the aspartate kinase and aspartate semialdehyde dehydrogenase ope-ron from mycobacteria.


In enzymology, an aspartate-semialdehyde dehydrogenase (EC is an enzyme that is very important in the biosynthesis of amino acids in prokaryotes, fungi, and some higher plants. It forms an early branch point in the metabolic ...


-aspartate semialdehyde dehydrogenase Methionine - New World EncyclopediaPeptide Synthesis, Custom Peptide, Peptide  mechanism for aspartate aminotransferaseAspartate-semialdehyde dehydrogenase β aspartate semialdehyde dehydrogenase




aspartate-semialdehyde dehydrogenase


  [★] アスパラギン酸アスパラギン酸塩

Aspasparticaspartic acidDL-aspartateL-aspartic acidmagnesium aspartatepotassium aspartate
aspartic acid


  [★] 脱水素酵素 デヒドロゲナーゼ


  [★] 脱水素酵素 デヒドロゲナーゼ