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「antineoplastic drug (trade name Elspar) sometimes used to treat lymphoblastic leukemia」

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/10/26 01:56:29」(JST)

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  • A temporal and spatial contribution of asparaginase to asparagine catabolism during development of rice grains.
  • Yabuki Y1, Ohashi M1, Imagawa F1, Ishiyama K1, Beier MP1, Konishi N1, Umetsu-Ohashi T1, Hayakawa T1, Yamaya T1, Kojima S2.
  • Rice (New York, N.Y.).Rice (N Y).2017 Dec;10(1):3. doi: 10.1186/s12284-017-0143-8. Epub 2017 Jan 25.
  • BACKGROUND: Asparagine is one of the most dominant organic nitrogen compounds in phloem and xylem sap in a wide range of plant species. Asparaginase (ASNase; EC, catabolizes asparagine into aspartate and ammonium; therefore, it is suggested to play a key role in asparagine metabolism within
  • PMID 28124210
  • Pegaspargase hypersensitivity reactions: intravenous infusion versus intramuscular injection - a review.
  • Beaupin LK1, Bostrom B2, Barth MJ1, Franklin I3, Jaeger R3, Kamath P3, Schreiber B3, Bleyer A4.
  • Leukemia & lymphoma.Leuk Lymphoma.2017 Apr;58(4):766-772. doi: 10.1080/10428194.2016.1218004. Epub 2016 Sep 19.
  • Pegaspargase is a mainstay in the treatment of acute lymphoblastic leukemia. When intravenous (IV) infusion replaced intramuscular (IM) injection as the standard route of administration, there were early reports suggested an increased hypersensitivity reactions (HSRs) rate with IV administration. Th
  • PMID 27643446
  • Comparison of a pediatric-inspired treatment protocol versus standard-intensity chemotherapy for young adults with standard-risk BCR-ABL negative acute lymphoblastic leukemia.
  • Kliman D1, Barnett M1, Broady R1, Forrest D1, Gerrie A1, Hogge D1, Nantel S1, Narayanan S1, Nevill T1, Power M1, Sanford D1, Song K1, Sutherland H1, Toze C1, Abou Mourad Y1.
  • Leukemia & lymphoma.Leuk Lymphoma.2017 Apr;58(4):909-915. doi: 10.1080/10428194.2016.1222376. Epub 2016 Aug 26.
  • We investigated the utility of a pediatric-inspired protocol in adults aged 18-40 years with standard-risk BCR-ABL negative acute lymphoblastic leukemia (ALL). Retrospective outcomes of 25 patients treated with a pediatric protocol between 2008 and 2014 were compared with 22 similarly aged patients
  • PMID 27561638


  • Reconstitution of L-Asparaginase in Siliconized Syringes with Shaking and Headspace Air Induces Protein Aggregation
  • 血液腫瘍に合併する血栓症とDICの病態と適切な管理 (特集 血液腫瘍診療において注意すべき病態,有害事象と管理)
  • L-Asparaginase monotherapy for EBV-positive T/NK lymphoproliferative diseases: A pilot Study


(a-SPARE-a-ji-naze) Trade names: Elspar ®, Kidrolase ® Other names: L-asparaginase, Erwinia L-asparaginase uses generic names in all descriptions of drugs. Elspar is the trade name for asparaginase. l ...
Asparaginase - Get up-to-date information on Asparaginase side effects, uses, dosage, overdose, pregnancy, alcohol and more. Learn more about Asparaginase ... Do not receive asparaginase if you are allergic to asparaginase or pegaspargase ...


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L-アスパラギナーゼ L-asparaginase L-ASP

  • 悪性リンパ腫治療薬


  [★] アスパラギナーゼL-アスパラギナーゼasparaginase