WordNet

free of or using methods to keep free of pathological microorganisms; "a sterile operating area"; "aseptic surgical instruments"; "aseptic surgical techniques" (同)sterile
infectious disease characterized by inflammation of the meninges (the tissues that surround the brain or spinal cord) usually caused by a bacterial infection; symptoms include headache and stiff neck and fever and nausea

PrepTutorEJDIC

(傷が)病原(腐敗)菌がついていない,無菌の;(包帯・ガーゼなどが)防腐処置をした
脳膜炎

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/08/02 08:19:04」(JST)

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Aseptic meningitis, or sterile meningitis, is a condition in which the layers lining the brain, meninges, become inflamed and a pyogenic bacterial source is not to blame. Meningitis is diagnosed on a history of characteristic symptoms and certain examination findings (e.g., Kernig's sign). Investigations should show an increase in the number of leukocytes present in the cerebrospinal fluid (CSF), obtained via lumbar puncture, (normal being fewer than five visible per microscopic High Power Field).

The term aseptic is frequently a misnomer, implying a lack of infection. On the contrary, many cases of aseptic meningitis represent infection with viruses^[1] or mycobacteria that cannot be detected with routine methods. While the advent of polymerase chain reaction has increased the ability of clinicians to detect viruses such as enterovirus, cytomegalovirus, and herpes virus in the CSF, many viruses can still escape detection. Additionally, mycobacteria frequently require special stains and culture methods that make their detection difficult. When CSF findings are consistent with meningitis, and microbiologic testing is unrevealing, clinicians typically assign the diagnosis of aseptic meningitis—making it a relative diagnosis of exclusion.

Aseptic meningitis can result from non-infectious causes; it is a relatively infrequent side effect of medications, and can be an early finding in autoimmune disease.

There is no formal classification system. It is usually by the causative organism if identified.

"Aseptic meningitis", like non-gonococcal urethritis, non-Hodgkin lymphoma and atypical pneumonia, merely states what a condition is not, not what a condition is. Terms such as viral meningitis, bacterial meningitis, fungal meningitis, neoplastic meningitis and drug-induced aseptic meningitis can provide more information about the condition, and without using one of these more specific terms, it is difficult to describe treatment options or prognosis.

Types of aseptic meningitis

Viral meningitis
Drug-induced aseptic meningitis
Neoplastic meningitis
Lyme disease
Mumps meningoencephalitis
Neurosarcoidosis

References

^ "aseptic meningitis" at Dorland's Medical Dictionary

UpToDate Contents

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1. 成人における無菌性髄膜炎 aseptic meningitis in adults
2. ウイルス性髄膜炎：小児における臨床的特徴および診断 viral meningitis clinical features and diagnosis in children
3. ウイルス性髄膜炎：小児におけるマネージメント、予後、および予防 viral meningitis management prognosis and prevention in children
4. 非プラチナ製剤ベースの癌化学療法の神経学的合併症の概要 overview of neurologic complications of non platinum cancer chemotherapy
5. COX-2選択的阻害剤の概要 overview of selective cox 2 inhibitors

English Journal

Relapsing Polychondritis with Central Nervous System Involvement: Experience of Three Different Cases in a Single Center.

Jeon CH1.
Journal of Korean medical science.J Korean Med Sci.2016 Nov;31(11):1846-1850. doi: 10.3346/jkms.2016.31.11.1846.
Relapsing polychondritis (RP) is an autoimmune disorder characterized by inflammation in cartilaginous structures including the ears, noses, peripheral joints, and tracheobronchial tree. It rarely involves the central nervous system (CNS) but diagnosis of CNS complication of RP is challenging becaus
PMID 27709866

Molecular characterization of environmental and clinical echovirus 6 isolates from Poland, 2006-2014.

Wieczorek M1, Krzysztoszek A2, Ciąćka A2, Figas A2.
Journal of medical virology.J Med Virol.2016 Oct 13. doi: 10.1002/jmv.24709. [Epub ahead of print]
The aim of this study was to investigate the genetic variability of echovirus 6 (E6) isolates from environmental samples and clinical cases of aseptic meningitis from 2006 to 2014. The analysis of the VP1 region showed the extensive diversity (up to 18.8%) and revealed that E6 circulating in Poland
PMID 27736044

Blood-CSF-barrier dysfunction is a marker for encephalitic involvement in patients with aseptic meningitis/meningoencephalitis.

Hoyer C1, Eisele P1, Ebert AD1, Schneider S2, Gass A1, Fatar M1, Szabo K1, Alonso A3.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology.J Clin Virol.2016 Oct 6;84:82-86. doi: 10.1016/j.jcv.2016.10.006. [Epub ahead of print]
BACKGROUND: The term "aseptic meningitis" encompasses cases of meningitis with negative bacterial CSF culture, which predominantly are of viral etiology. While the clinical course is usually benign, complications such as encephalitic involvement resulting in a more severe clinical course may occur.
PMID 27736668

Japanese Journal

パレコウイルス3型による無菌性髄膜炎の流行解析

神奈川県衛生研究所研究報告 (45), 19-23, 2015-09
NAID 40020611934

無菌性髄膜炎患者からエコーウイルス3型の検出

長野県環境保全研究所研究報告 (11), 41-44, 2015
NAID 40020638587

麻疹・風疹・ムンプスワクチン混合(MMR)ワクチンの復活を目指して (特集 TVF)

バムサジャーナル = The journal of biomedical science and biosafety 27(3), 120-126,図巻頭1枚, 2015
NAID 40020629360

「無菌性髄膜炎」

Aseptic meningitis
Classification and external resources
Specialty	neurology
ICD-10	G03 Nonpyogenic meningitis
ICD-9-CM	322.0 Nonpyogenic meningitis
DiseasesDB	945
MedlinePlus	000614
eMedicine	NEURO/697
MeSH	D008582