人工肺
WordNet
- not arising from natural growth or characterized by vital processes
- artificially formal; "that artificial humility that her husband hated"; "contrived coyness"; "a stilted letter of acknowledgment"; "when people try to correct their speech they develop a stilted pronunciation" (同)contrived, hokey, stilted
- contrived by art rather than nature; "artificial flowers"; "artificial flavoring"; "an artificial diamond"; "artificial fibers"; "artificial sweeteners" (同)unreal
- either of two saclike respiratory organs in the chest of vertebrates; serves to remove carbon dioxide and provide oxygen to the blood
PrepTutorEJDIC
- 『人造の』,『人工の』,人為的な / 模造の / 不自然な,見せかけの
- 《しばしば複数形で》『肺』,肺臓
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/03/29 13:29:04」(JST)
[Wiki en表示]
An artificial lung (AL) is a prosthetic device that provides oxygenation of blood and removal of carbon dioxide from blood. The AL is intended to take over some of the functionality of biological lungs. It is different from a heart-lung machine in that it is internal and designed to take over the functions of the lungs for long periods of time rather than on a temporary basis.
The heart lung machine inspired the design of AL devices, however modern ALs are optimized to minimize patient trauma. Following the development of the heart lung machine, Extracorporeal Membrane Oxygenation (ECMO) was developed. This was intended to be used as a bridge to lung transplant (BTT), for patients too sick to wait until a donor lung was available. Mechanical Ventilation (MV) has also been used, however is damaging to the patients lungs if used for extended periods of time. Both these therapies are expensive and are associated with poor quality of life, in part due to patient immobility and the complex blood circuit.
Recent developments include simplifying the ECMO system, and devices that use 380 micron wide hollow fibers to simulate the function of alveoli have been developed. Several research groups, notably, the University of Pittsburgh,[1] University of Michigan, University of Maryland and Boston based groups are developing AL devices to bridge patients to lung transplant.[2][3]
See also
- Extracorporeal membrane oxygenation
- Heart-lung machine
- Lung transplantation
- Medical ventilator
References
- ^ "Wearable Artificial Lung to Be Developed at Pitt Through $3.4 Million Grant". pitt.edu.
- ^ "UMHS News Release". umich.edu. Archived from the original on 14 June 2007.
- ^ "Artificial lung mimics real organ’s design and efficiency - think:blog". case.edu.
UpToDate Contents
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- 1. 肺移植：死亡ドナーの評価およびマネージメント lung transplantation deceased donor evaluation and management
- 2. 肺癌のスクリーニング screening for lung cancer
- 3. 肺移植：ドナー肺の保存 lung transplantation donor lung preservation
- 4. 肺移植：概要 lung transplantation an overview
- 5. 心肺移植 heart lung transplantation
English Journal
- Prevention of rejection of allogeneic endothelial cells in a biohybrid lung by silencing HLA-class I expression.
- Wiegmann B1, Figueiredo C2, Gras C3, Pflaum M4, Schmeckebier S4, Korossis S5, Haverich A1, Blasczyk R3.
- Biomaterials.Biomaterials.2014 Sep;35(28):8123-33. doi: 10.1016/j.biomaterials.2014.06.007. Epub 2014 Jun 21.
- Variability in Human Leukocyte Antigens (HLA) remains a hurdle to the application of allogeneic cellular products. Due to insufficient autologous endothelial cell harvesting for the biohybrid lung, allogeneic human cord blood derived endothelial cells (HCBEC) were used for the endothelialization of
- PMID 24961166
- Improvement of pulmonary surfactant activity by introducing D-amino acids into highly hydrophobic amphiphilic α-peptide Hel 13-5.
- Nakamura Y1, Yukitake K2, Nakahara H3, Lee S4, Shibata O5, Lee S6.
- Biochimica et biophysica acta.Biochim Biophys Acta.2014 Aug;1838(8):2046-52. doi: 10.1016/j.bbamem.2014.04.024. Epub 2014 May 2.
- The high costs of artificial pulmonary surfactants, ranging in hundreds per kilogram of body weight, used for treating the respiratory distress syndrome (RDS) premature babies have limited their applications. We have extensively studied soy lecithins and higher alcohols as lipid alternatives to expe
- PMID 24796503
- The application of single-lumen endotracheal tube anaesthesia with artificial pneumothorax in thoracolaparoscopic oesophagectomy.
- Zhang R1, Liu S1, Sun H1, Liu X1, Wang Z1, Qin J1, Hua X1, Li Y2.
- Interactive cardiovascular and thoracic surgery.Interact Cardiovasc Thorac Surg.2014 Aug;19(2):308-10. doi: 10.1093/icvts/ivu100. Epub 2014 Apr 15.
- Double-lumen endotracheal tube (DLET) anaesthesia is the commonly used method in minimally invasive oesophagectomy (MIE). However, DLET intubation does have its disadvantages. Firstly, the placement of the DLET needs a skilled anaesthetist with familiarity of the technique and subsequent ability to
- PMID 24740912
Japanese Journal
- Computed Tomography-guided Radiofrequency Ablation for Subdiaphragm Hepatocellular Carcinoma: Safety and Efficacy of Inducing an Artificial Pneumothorax
- 1E26 4D肺亜細葉モデルによる気流・血流・拡散シミュレーション
- 1A25 人工心肺自動制御化のための圧力センサを用いた貯血槽の貯血レベル計測に関する調査
Related Links
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★リンクテーブル★
[★]
- 英
- oxygenator, artificial lung
[★]
- 関
- artificially