aromatase

出典: meddic

アロマターゼ

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/05/25 13:44:35」(JST)

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英文文献

  • Overcoming acquired resistance to letrozole by targeting the PI3K/AKT/mTOR pathway in breast cancer cell clones.
  • Cavazzoni A, Bonelli MA, Fumarola C, La Monica S, Airoud K, Bertoni R, Alfieri RR, Galetti M, Tramonti S, Galvani E, Harris AL, Martin LA, Andreis D, Bottini A, Generali D, Petronini PG.SourceDepartment of Experimental Medicine, Unit of Experimental Oncology, University of Parma, Italy.
  • Cancer letters.Cancer Lett.2012 Oct 1;323(1):77-87. Epub 2012 Apr 3.
  • Development of resistance to endocrine therapy is a clinical issue in estrogen receptor (ER)-positive breast cancer. Here we show that persistent activation of AKT/mTOR signaling is crucial to the acquisition of letrozole resistance in cell clones generated from MCF-7/AROM-1 aromatase-expressing bre
  • PMID 22484466
  • Antiresorptive therapies in oncology and their effects on cancer progression.
  • Bundred N.SourceDepartment of Surgery, University Hospital of South Manchester, Manchester, United Kingdom.
  • Cancer treatment reviews.Cancer Treat Rev.2012 Oct;38(6):776-86. Epub 2012 Feb 26.
  • Bone health is an emerging concern in the early breast cancer setting. Current adjuvant therapies, especially hormonal therapies in premenopausal patients (e.g. goserelin) and aromatase inhibitors in postmenopausal patients, have been associated with substantial decreases in bone mineral density tha
  • PMID 22370427

和文文献

  • Structure and functions of the placenta in common minke (Balaenoptera acutorostrata), Bryde's (B. brydei) and sei (B. borealis) whales
  • The journal of reproduction and development 61(5), 415-421, 2015-10
  • NAID 40020623606
  • Neoadjuvant Chemotherapy with or without Concurrent Hormone Therapy in Estrogen Receptor-Positive Breast Cancer:NACED-Randomized Multicenter Phase II Trial
  • 閉経前ホルモン受容体陽性早期乳がんに対する術後内分泌療法 (特集 早期乳がんおよび進行乳がんに対する新しい標準治療の開発)

関連リンク

Aromatase, also called estrogen synthetase or estrogen synthase, is an enzyme responsible for a key step in the biosynthesis of estrogens. It is a member of the cytochrome P450 superfamily (EC 1.14.14.1), which are monooxygenases that ...
Aromatase inhibitors work by inhibiting the action of the enzyme aromatase, which converts androgens into estrogens by a process called aromatization. As breast tissue is stimulated by estrogens, decreasing their production is a way of ...

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★リンクテーブル★
リンク元hypoestrogenism」「CYP19」「アロマターゼ」「芳香化酵素
拡張検索aromatase inhibitor」「aromatase inhibitors

hypoestrogenism」

  [★] 低エストロゲン症

In the ovary, PRL blocks folliculogenesis and inhibits granulosa cell aromatase activity, leading to hypoestrogenism and anovulation.(HIM.2204)


CYP19」

  [★]

aromatase
  • aromatase


アロマターゼ」

  [★]

aromatase
P450arom
[[]]


芳香化酵素」

  [★]

aromatase
アロマターゼ


aromatase inhibitor」

  [★]

アロマターゼ阻害薬アロマターゼ阻害剤アロマターゼインヒビター

aromatase inhibitors」

  [★] アロマターゼ阻害薬




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