WordNet

(medicine) the invasion of the body by pathogenic microorganisms and their multiplication which can lead to tissue damage and disease
(phonetics) the alteration of a speech sound under the influence of a neighboring sound
the pathological state resulting from the invasion of the body by pathogenic microorganisms
(international law) illegality that taints or contaminates a ship or cargo rendering it liable to seizure
moral corruption or contamination; "ambitious men are led astray by an infection that is almost unavoidable"
an incident in which an infectious disease is transmitted (同)contagion, transmission
animal viruses belonging to the family Arenaviridae

PrepTutorEJDIC

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

Delayed inflammatory and cell death responses are associated with reduced pathogenicity in lujo virus-infected cynomolgus macaques.

Rasmussen AL1, Tchitchek N1, Safronetz D2, Carter VS1, Williams CM1, Haddock E2, Korth MJ1, Feldmann H2, Katze MG3.
Journal of virology.J Virol.2015 Mar 1;89(5):2543-52. doi: 10.1128/JVI.02246-14. Epub 2014 Dec 17.
To identify host factors associated with arenavirus virulence, we used a cynomolgus macaque model to evaluate the pathogenesis of Lujo virus (LUJV), a recently emerged arenavirus that caused an outbreak of severe viral hemorrhagic fever in southern Africa. In contrast to human cases, LUJV caused mil
PMID 25520505

Inhibition of the PI3K/Akt pathway by Ly294002 does not prevent establishment of persistent Junín virus infection in Vero cells.

Linero FN1, Fernández Bell-Fano PM, Cuervo E, Castilla V, Scolaro LA.
Archives of virology.Arch Virol.2015 Feb;160(2):469-75. doi: 10.1007/s00705-014-2298-6. Epub 2014 Dec 7.
In previous work, we demonstrated that the arenavirus Junín virus (JUNV) is able to activate Akt by means of the phosphatidylinositol-3-kinase (PI3K) survival pathway during virus entry. This work extends our study, emphasizing the relevance of this pathway in the establishment and maintenance of p
PMID 25488290

Vaccine-elicited CD4 T cells induce immunopathology after chronic LCMV infection.

Penaloza-MacMaster P1, Barber DL2, Wherry EJ3, Provine NM1, Teigler JE1, Parenteau L1, Blackmore S1, Borducchi EN1, Larocca RA1, Yates KB4, Shen H3, Haining WN4, Sommerstein R5, Pinschewer DD6, Ahmed R7, Barouch DH8.
Science (New York, N.Y.).Science.2015 Jan 16;347(6219):278-82. doi: 10.1126/science.aaa2148.
CD4 T cells promote innate and adaptive immune responses, but how vaccine-elicited CD4 T cells contribute to immune protection remains unclear. We evaluated whether induction of virus-specific CD4 T cells by vaccination would protect mice against infection with chronic lymphocytic choriomeningitis v
PMID 25593185