ア・リ・タンパク質E4
- 関
- apoE4
WordNet
- the 5th letter of the Roman alphabet (同)e
UpToDate Contents
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- 1. アルツハイマー病の遺伝学 genetics of alzheimer disease
- 2. リポ蛋白の分類、代謝、およびアテローム性動脈硬化症における役割 lipoprotein classification metabolism and role in atherosclerosis
- 3. LDLコレステロール代謝の遺伝性疾患 inherited disorders of ldl cholesterol metabolism
- 4. 軽度認知機能障害：予後および治療 mild cognitive impairment prognosis and treatment
- 5. アルツハイマー病の疫学、病理、および病因 epidemiology pathology and pathogenesis of alzheimer disease
English Journal
- The potential of apolipoprotein E4 to act as a substrate for primary cultures of hippocampal neurons.
- Kim KM, Vicenty J, Palmore GT.SourceSchool of Engineering, Brown University, Providence, RI 02912, USA; Center for Biomedical Engineering, Brown University, Providence, RI 02912, USA.
- Biomaterials.Biomaterials.2013 Apr;34(11):2694-700. doi: 10.1016/j.biomaterials.2013.01.012. Epub 2013 Jan 23.
- The E4 isoform of apolipoprotein (apoE4) is known to be a major risk factor for Alzheimer's Disease (AD). Previous in vitro studies have shown apoE4 to have a negative effect on neuronal outgrowth when incubated with lipids. The effect of apoE4 itself on the development of neurons from the central
- PMID 23352042
- Default mode network activity and white matter integrity in healthy middle-aged ApoE4 carriers.
- Patel KT, Stevens MC, Pearlson GD, Winkler AM, Hawkins KA, Skudlarski P, Bauer LO.SourceOlin Neuropsychiatry Research Center, Institute of Living at Hartford Hospital, 200 Retreat Avenue, Hartford, CT, 06106, USA, Kpancholi@harthosp.org.
- Brain imaging and behavior.Brain Imaging Behav.2013 Mar;7(1):60-7. doi: 10.1007/s11682-012-9187-y.
- Alzheimer's disease (AD) is most commonly detected during old age, but the underlying neuropathologic changes likely appear decades earlier, especially among patients possessing genetic risk factors, such as the isoform E4 of the apolipoprotein E (ApoE4). In this study, we used magnetic resonance im
- PMID 23011382
- A silent mutation of Niemann-Pick C1-like 1 and apolipoprotein E4 modulate cholesterol absorption in primary hyperlipidemias.
- Lupattelli G, Pisciotta L, De Vuono S, Siepi D, Bellocchio A, Melis F, Bertolini S, Pirro M, Mannarino E.SourceDepartment of Clinical and Experimental Medicine, Internal Medicine, Angiology and Atherosclerosis, "Santa Maria della Misericordia" Hospital, Piazzale Menghini, Sant'Andrea delle Fratte, University of Perugia, Perugia, 06132, Italy. Electronic address: glupa@unipg.it.
- Journal of clinical lipidology.J Clin Lipidol.2013 Mar;7(2):147-52. doi: 10.1016/j.jacl.2012.12.003. Epub 2012 Dec 20.
- OBJECTIVE: To investigate the influence of the silent mutation c.816C > G (L272) of Niemann-Pick C1-like 1 (NPC1L1) and of apolipoprotein (APO) E alleles on cholesterol absorption markers, sitosterol and campesterol, in 87 patients with primary hyperlipidemias.METHODS: In all subjects genotyped
- PMID 23415434
Japanese Journal
- Polymorphisms of the ApoE (Apolipoprotein E) Gene and Their Influence on Dyslipidemia in HIV-1-Infected Individuals
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- Japanese Journal of Infectious Diseases 68(1), 5-12, 2015
- … The purpose of this retrospective case-control study was to investigate the frequency of Apolipoprotein E (ApoE) polymorphisms and their influence on antiretroviral therapy (ART)-induced lipodystrophy or dyslipidemia in HIV-infected Thai patients. …
- NAID 130004757124
- The distribution of Apolipoprotein E gene polymorphism and their influences in dyslipidemias in HIV-1 infections
- , , , , , , , ,
- Japanese Journal of Infectious Diseases, 2014
- … The purpose of this study was to investigate the frequency of ApoE (Apolipoprotein E) polymorphisms and their influence on antiretroviral therapy (ART) induced lipodystrophy/dyslipidemia in HIV-infected Thai patients. … Among 85 patients ApoE genotypes frequencies were 2.35% (n=2) for E2/E2, 20% (n=17) for E2/E3, 9.41% (n=8) for E2/E4, 36.47% (n=31) for E3/E3, 30.59% (n=26) for E3/E4 and 1.18% (n=1) for E4/E4. …
- NAID 130004716731
- Influence of Domain Stability on the Properties of Human Apolipoprotein E3 and E4 and Mouse Apolipoprotein E
- Nguyen D,Dhanasekaran P,Nickel M,Mizuguchi C,Watanabe M,Saito H,Phillips MC,Lund-Katz S
- BIOCHEMISTRY 53(24), 4025-4033, 2014
- NAID 120005597143
Related Links
- E3 (rs429358) is found in approximately 79 percent of the population. It is considered the "neutral" Apo E genotype. E4 is found in approximately 14 percent of the population. E4 has been implicated in atherosclerosis and Alzheimer's disease, ...
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| リンク元 | 「apoE4」「アポリポタンパク質E4」 |
| 関連記事 | 「apolipoprotein」「apolipoproteins」「E」 |
「apoE4」
- ア・リ・タンパク質E4、ア・リ・蛋白E4、ア・E4
「アポリポタンパク質E4」
「apolipoprotein」
- 関
- apo
「apolipoproteins」
「E」