aorta

出典: meddic

大動脈 Ao

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「the large trunk artery that carries blood from the left ventricle of the heart to branch arteries」

PrepTutorEJDIC   license prepejdic

「大動脈」

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/06/24 08:28:32」(JST)

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  • Stretchable electrochemical impedance sensors for intravascular detection of lipid-rich lesions in New Zealand White rabbits.
  • Cao H1, Yu F2, Zhao Y3, Scianmarello N3, Lee J1, Dai W4, Jen N1, Beebe T1, Li R1, Ebrahimi R5, Chang DS5, Mody FV5, Pacella J6, Tai YC3, Hsiai T7.Author information 1Department of Biomedical Engineering, University of Southern California, Los Angeles, CA, United States; Division of Cardiology, Department of Medicine, VA Greater Los Angeles Healthcare System, School of Medicine, University of California, United States.2Department of Biomedical Engineering, University of Southern California, Los Angeles, CA, United States.3Department of Electrical Engineering, California Institute of Technology, Pasadena, CA, United States.4The Heart Institute of Good Samaritan Hospital, Los Angeles, CA, United States.5Division of Cardiology, Department of Medicine, VA Greater Los Angeles Healthcare System, School of Medicine, University of California, United States.6Division of Cardiology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, United States.7Department of Biomedical Engineering, University of Southern California, Los Angeles, CA, United States; Division of Cardiology, Department of Medicine, VA Greater Los Angeles Healthcare System, School of Medicine, University of California, United States. Electronic address: THsiai@mednet.ucla.edu.AbstractFlexible electronics have enabled catheter-based intravascular sensing. However, real-time interrogation of unstable plaque remains an unmet clinical challenge. Here, we demonstrate the feasibility of stretchable electrochemical impedance spectroscopy (EIS) sensors for endoluminal investigations in New Zealand White (NZW) rabbits on diet-induced hyperlipidemia. A parylene C (PAC)-based EIS sensor mounted on the surface of an inflatable silicone balloon affixed to the tip of an interrogating catheter was deployed (1) on the explants of NZW rabbit aorta for detection of lipid-rich atherosclerotic lesions, and (2) on live animals for demonstration of balloon inflation and EIS measurements. An input peak-to-peak AC voltage of 10 mV and sweeping-frequency from 300 kHz to 100 Hz were delivered to the endoluminal sites. Balloon inflation allowed EIS sensors to be in contact with endoluminal surface. In the oxidized low-density-lipoprotein (oxLDL)-rich lesions from explants of fat-fed rabbits, impedance magnitude increased significantly by 1.5-fold across the entire frequency band, and phase shifted ~5° at frequencies below 10 kHz. In the lesion-free sites of the normal diet-fed rabbits, impedance magnitude increased by 1.2-fold and phase shifted ~5° at frequencies above 30 kHz. Thus, we demonstrate the feasibility of stretchable intravascular EIS sensors for identification of lipid rich lesions, with a translational implication for detecting unstable lesions.
  • Biosensors & bioelectronics.Biosens Bioelectron.2014 Apr 15;54:610-6. doi: 10.1016/j.bios.2013.11.059. Epub 2013 Dec 1.
  • Flexible electronics have enabled catheter-based intravascular sensing. However, real-time interrogation of unstable plaque remains an unmet clinical challenge. Here, we demonstrate the feasibility of stretchable electrochemical impedance spectroscopy (EIS) sensors for endoluminal investigations in
  • PMID 24333932
  • Serum Bilirubin Level and Aortic Intima-Media Thickness in Patients Without Clinical Manifestation of Atherosclerotic Cardiovascular Disease.
  • Kalkan GY1, Gür M, Baykan AO, Koyunsever NY, Kaypakl X0131 O, Sen O, Kulo X011f Lu O, Seker T, Uçar H, Akyol S, Elbasan Z, Sahin DY, Cayl X0131 M.Author information 11Department of Cardiology, Adana Numune Training and Research Hospital, Adana, Turkey.AbstractWe investigated the association between serum bilirubin level and thoracic aortic intima-media thickness (IMT). The study population consisted of 417 patients without coronary artery disease, who underwent transesophageal echocardiography examination for various indications. The highest aortic IMT values were observed in the bilirubinlow group compared with the bilirubinhigh group (P < .001). Serum bilirubin level was associated with high-density lipoprotein cholesterol level (r = .162, P = .001), high-sensitivity C-reactive protein (hsCRP; r = -.265, P < .001), and aortic IMT (r = -.551, P < .001) in bivariate analysis. Multivariate linear regression analysis showed that serum bilirubin level was independently and negatively associated with hsCRP (β = -.095, P = .028) and aortic IMT (β = -.513, P < .001). Serum bilirubin level may be an independent predictor of the extent of subclinical aortic atherosclerosis assessed by thoracic aortic IMT.
  • Angiology.Angiology.2014 Apr;65(4):308-312. Epub 2013 Oct 24.
  • We investigated the association between serum bilirubin level and thoracic aortic intima-media thickness (IMT). The study population consisted of 417 patients without coronary artery disease, who underwent transesophageal echocardiography examination for various indications. The highest aortic IMT v
  • PMID 24163123
  • Involvement of proteinase activated receptor-2 in the vascular response to sphingosine 1-phosphate.
  • Roviezzo F1, De Angelis A2, De Gruttola L1, Bertolino A1, Sullo N2, Brancaleone V3, Bucci M1, De Palma R4, Urbanek K2, D'Agostino B2, Ianaro A1, Sorrentino R1, Cirino G1.Author information 1*Dipartimento di Farmacia, Università di Napoli Federico II, Napoli, Italy.2†Dipartimento di Medicina Sperimentale, Sezione di Farmacologia L. Donatelli, Seconda Università degli Studi di Napoli, Napoli, Italy.3‡Dipartimento di Chimica, Università degli Studi della Basilicata, Pontenza, Italy.4§Dipartimento di Internistica Clinica e Sperimentale, Seconda Università degli Studi di Napoli, Napoli, Italy.AbstractS1P (sphingosine 1-phosphate) represents one of the key latest additions to the list of vasoactive substances that modulate vascular tone. PAR-2 (proteinase activated receptor-2) has been shown to be involved in cardiovascular function. In the present study, we investigated the involvement of PAR-2 in S1P-induced effect on vascular tone. The present study has been performed by using isolated mouse aortas. Both S1P and PAR-2 agonists induced endothelium-dependent vasorelaxation. L-NAME (N(G)-nitro-L-arginine methyl ester) and wortmannin abrogated the S1P-induced vasorelaxatioin, while significantly inhibiting the PAR-2-mediated effect. Either ENMD1068, a PAR-2 antagonist, or gabexate, a serine protease inhibitor, significantly inhibited S1P-induced vasorelaxation. Aortic tissues harvested from mice overexpressing PAR-2 displayed a significant increase in vascular response to S1P as opposed to PAR-2-null mice. Immunoprecipitation and immunofluorescence studies demonstrated that S1P(1) interacted with PAR-2 and co-localized with PAR-2 on the vascular endothelial surface. Furthermore, S1P administration to vascular tissues triggered PAR-2 mobilization from the plasma membrane to the perinuclear area; S1P-induced translocation of PAR-2 was abrogated when aortic rings were pre-treated with ENMD1068 or when caveolae dysfunction occurred. Similarly, experiments performed in cultured endothelial cells (human umbilical vein endothelial cells) showed a co-localization of S1P(1) and PAR2, as well as the ability of S1P to induce PAR-2 trafficking. Our results suggest that S1P induces endothelium-dependent vasorelaxation mainly through S1P(1) and involves PAR-2 transactivation.
  • Clinical science (London, England : 1979).Clin Sci (Lond).2014 Apr;126(8):545-56. doi: 10.1042/CS20130272.
  • S1P (sphingosine 1-phosphate) represents one of the key latest additions to the list of vasoactive substances that modulate vascular tone. PAR-2 (proteinase activated receptor-2) has been shown to be involved in cardiovascular function. In the present study, we investigated the involvement of PAR-2
  • PMID 24131465

関連リンク

aorta(アオルタ)は2004年に結成された日本のロックバンド。男性4人によって構成され る。耳に残るメロディーと景色を想起させる独特の世界観を特徴とする音楽を展開する。 目次. 1 概要・来歴; 2 メンバー; 3 作品. 3.1 シングル; 3.2 アルバム; 3.3 配信. 4 外部 ...

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★リンクテーブル★
国試過去問103C010
リンク元大動脈」「aortal」「aortic」「aortae」「Ao
拡張検索abdominal aorta」「chronic occlusion of the terminal abdominal aorta

103C010」

  [★]

  • 組合せで誤っているのはどれか。
[正答]


※国試ナビ4※ 103C009]←[国試_103]→[103C011

大動脈」

  [★]

aorta (Z), Ao
大動脈弁
  • 大動脈径:胸骨左縁アプローチで左室長軸断面を得て、心エコーMモードで評価。




aortal」

  [★]

  • 大動脈の
aortaaortaeaortic

WordNet   license wordnet

「of or relating to the aorta」
aortic


aortic」

  [★]

  • adj.
  • 大動脈の
aortaaortaeaortal


aortae」

  [★]

大動脈

aortaaortalaortic


Ao」

  [★]

aorta, 大動脈

大動脈 aorta


abdominal aorta」

  [★] 腹部大動脈腹大動脈


chronic occlusion of the terminal abdominal aorta」

  [★] 大動脈分岐部慢性閉塞症


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