WordNet
- a substance that exerts some force or effect
- a businessman who buys or sells for another in exchange for a commission (同)factor, broker
- any agent or representative of a federal agency or bureau (同)federal agent
- a representative who acts on behalf of other persons or organizations
- an active and efficient cause; capable of producing a certain effect; "their research uncovered new disease agents"
- how long something has existed; "it was replaced because of its age"
- a time of life (usually defined in years) at which some particular qualification or power arises; "she was now of school age"; "tall for his eld" (同)eld
- begin to seem older; get older; "The death of his wife caused him to age fast"
- make older; "The death of his child aged him tremendously"
PrepTutorEJDIC
- 『代理人』;周旋人 / 働き(作用)を起こすもの;作用物,薬剤 / (政府機関,特にFBI,CIAなどの)部員,機関員
- 〈U〉(一般に)『年齢』,寿命;〈C〉(個々の)『年齢』,年 / 〈U〉成年(おとなとしての資格・権利を得る年齢;通例18または21歳) / 〈U〉『老齢』;《集合的に》老人たち / 〈U〉(人生の)『一時期』;〈C〉世代(generation) / 〈U〉〈C〉《しばしばA-》(歴史上の)『時代』 / 〈C〉《話》長い間 / 年をとる,ふける;〈物が〉古くなる / 〈年〉'を'とらせる;〈物〉'を'古びさせる
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- 1. セカンドラインの抗結核療法 second line antituberculous therapy
- 2. HIV陰性患者における肺結核の治療 treatment of pulmonary tuberculosis in hiv negative patients
- 3. HIV感染患者における潜在結核感染の治療 treatment of latent tuberculosis infection in hiv infected patients
- 4. イソニアジド肝毒性 isoniazid hepatotoxicity
- 5. 結核性心膜炎 tuberculous pericarditis
English Journal
- Evolution of Mycolic Acid Biosynthesis Genes and Their Regulation during Starvation in Mycobacterium tuberculosis.
- Jamet S1, Quentin Y2, Coudray C1, Texier P3, Laval F1, Daffé M1, Fichant G4, Cam K5.
- Journal of bacteriology.J Bacteriol.2015 Dec;197(24):3797-811. doi: 10.1128/JB.00433-15. Epub 2015 Sep 28.
- Mycobacterium tuberculosis, the etiological agent of tuberculosis, is a Gram-positive bacterium with a unique cell envelope composed of an essential outer membrane. Mycolic acids, which are very-long-chain (up to C100) fatty acids, are the major components of this mycomembrane. The enzymatic pathway
- PMID 26416833
- [Fixed drug eruption after taking ethambutol].
- Bakayoko AS1, Kaloga M2, Kamagate M3, Kone Z4, Daix AT4, Ohui E4, Gbery I2, Domoua K4.
- Revue des maladies respiratoires.Rev Mal Respir.2015 Jan;32(1):48-51. doi: 10.1016/j.rmr.2014.03.011. Epub 2014 Apr 29.
- INTRODUCTION: Fixed drug eruption (FDE) is a specific skin reaction and the only exclusively medicinal dermatosis. Among the drugs usually responsible are the antituberculous antibiotics including rifampicin and, less often, isoniazid and pyrazinamide. FDE after taking ethambutol is rarely described
- PMID 25618204
- Topical application of zinc oxide nanoparticles reduces bacterial skin infection in mice and exhibits antibacterial activity by inducing oxidative stress response and cell membrane disintegration in macrophages.
- Pati R1, Mehta RK1, Mohanty S1, Padhi A1, Sengupta M1, Vaseeharan B2, Goswami C3, Sonawane A4.
- Nanomedicine : nanotechnology, biology, and medicine.Nanomedicine.2014 Aug;10(6):1195-208. doi: 10.1016/j.nano.2014.02.012. Epub 2014 Mar 6.
- Here we studied immunological and antibacterial mechanisms of zinc oxide nanoparticles (ZnO-NPs) against human pathogens. ZnO-NPs showed more activity against Staphylococcus aureus and least against Mycobacterium bovis-BCG. However, BCG killing was significantly increased in synergy with antitubercu
- PMID 24607937
Japanese Journal
- 肺結核短期強化療法に用いる Pyrazinamide の副作用である高尿酸血症の疫学調査
- 滝 久司,小川 賢二,村上 達也,二改 俊章
- 結核 83(7), 497-501, 2008-07-15
- … [Purpose] Pyrazinamide is an antituberculous drug that is administered as a two-month course during treatment of pulmonary tuberculosis. … Pyrazinamide is an important agent for intensive short-term antituberculous therapy. …
- NAID 10025688766
- 新規抗結核薬であるOPC-67683の研究開発
- 松本 真
- 結核 82(10), 792-794, 2007-10-15
- NAID 10020176289
- Unusual Meningeal Tuberculoma : Case Report
- OKADA Tomohisa,YOSHIDA Tazuka,ASAI Takahiko,SHINTANI Akira
- Neurologia medico-chirurgica 33(10), 710-712, 1993-10-15
- … Multiple antituberculous agent therapy resolved the papilledema and reduced the tumor. …
- NAID 110002278486
Related Pictures
★リンクテーブル★
| リンク元 | 「抗結核薬」 |
| 関連記事 | 「agent」「antituberculous」「age」 |
「抗結核薬」
- 英
- antituberculous, antitubercular agent antituberculous agent antitubercular drug antituberculous drug antituberculosis drugs, antituberculotic
- 同
- 抗結核剤
- 関
- 結核
- first aid step1 2006 p.172
抗結核薬一覧
- 覚え方：INH-SM-PZA-INH-RFP-EB → INH-SPIRE(inspire)
- イソニアジドだけは予防薬として用いられる(first aid step1 2006 p.172)
- 2nd line drugとしてcycloserineがある。
作用点
- エタンブトール：アラビノース転位酵素を阻害してarabinogalactanの合成を阻害。静菌的に作用。
- ピラジナミド ：ミコール酸合成を阻害(FAS1)
- イソニアジド ：ミコール酸合成を阻害(FAS2)。殺菌的に作用。
抗結核薬の副作用
- 前述した5種類の抗結核薬は全て肝毒性を有する。
- イソニアジド：末梢神経炎(ビタミンB6欠乏)、肝障害
- エタンブトール：視力障害(視力低下、中心暗点、視野狭窄、色神異常など)
- ピラジナミド：肝毒性、多発関節痛
- リファンピシン：白血球減少、血小板減少、発疹、肝障害
- ストレプトマイシン：CN VIII障害(難聴、めまい、耳鳴り)、腎機能障害
「agent」
- n.
- 代行者、代理人。代理業者
- 政府職員、官吏
- ある後位をする人、ある作用をするもの。動員、動力因、作用因。(文法)動作主。科学的変化を起こさせるもの、薬品、～剤。病原体
- 関
- agonist、agonistic、attorney、delegate、drug、etiologic agent、fomes、fomites、mediator、pathogen、pathogenic、pharmaceutical preparation、vector、vehicle
「antituberculous」
- adj.
- 関
- antitubercular agent、antitubercular drug、antituberculosis、antituberculous agent、antituberculous drug
「age」
- n.
- 年齢、歳
- v.
- 加齢する、熟成する