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1. HIV感染患者における結核の疫学、臨床症状、および診断 epidemiology clinical manifestations and diagnosis of tuberculosis in hiv infected patients
2. HIV感染患者における肺結核の治療 treatment of pulmonary tuberculosis in the hiv infected patient
3. 心臓移植における免疫抑制療法の導入および維持 induction and maintenance of immunosuppressive therapy in cardiac transplantation
4. 広範囲薬剤耐性結核の臨床症状、診断、および治療 clinical manifestations diagnosis and treatment of extensively drug resistant tuberculosis

English Journal

Library of diversely substituted 2-(quinolin-4-yl)imidazolines delivers novel non-cytotoxic antitubercular leads.

Krasavin M1, Mujumdar P2, Parchinsky V3, Vinogradova T4, Manicheva O4, Dogonadze M4.
Journal of enzyme inhibition and medicinal chemistry.J Enzyme Inhib Med Chem.2016 Dec;31(6):1146-55. doi: 10.3109/14756366.2015.1101094. Epub 2015 Nov 2.
A novel library based on quinolin-4-ylimidazoline core was designed to incorporate a general quinoline antimicrobial pharmacophore. A synthesis of the well-characterized library of 36 compounds was achieved using the Pd-catalyzed Buchwald-Hartwig-type imidazoline arylation chemistry developed earlie
PMID 26526717

Synthesis and biological activity of furoxan derivatives against Mycobacterium tuberculosis.

Fernandes GF1, de Souza PC1, Marino LB1, Chegaev K2, Guglielmo S2, Lazzarato L2, Fruttero R2, Chung MC1, Pavan FR1, Dos Santos JL3.
European journal of medicinal chemistry.Eur J Med Chem.2016 Nov 10;123:523-31. doi: 10.1016/j.ejmech.2016.07.039. Epub 2016 Jul 21.
Tuberculosis (TB) remains a serious health problem responsible to cause millions of deaths annually. The scenario becomes alarming when it is evaluated that the number of new drugs does not increase proportionally to the emergence of resistance to the current therapy. Furoxan derivatives, known as n
PMID 27508879

Comparative analysis of new peptide conjugates of antitubercular drug candidates-Model membrane and in vitro studies.

Ábrahám Á1, Baranyai Z2, Gyulai G1, Pári E1, Horváti K2, Bősze S2, Kiss É3.
Colloids and surfaces. B, Biointerfaces.Colloids Surf B Biointerfaces.2016 Nov 1;147:106-15. doi: 10.1016/j.colsurfb.2016.07.054. Epub 2016 Jul 28.
Novel peptide conjugates of two antitubercular drug candidates were synthesised and characterised using new tuftsin peptide derivative (OT14) as carrier moiety. As antitubercular drug candidates two pyridopyrimidine derivatives, TB803 (2-allylamino-4-oxopyrido[1,2-a]pyrimidine-3-carbaldehyde) and TB
PMID 27497074

Synthesis and in Vitro Evaluation of the Antitubercular and Antibacterial Activity of Novel Oxazolidinones Bearing Octahydrocyclopenta[c]pyrrol-2-yl Moieties

Task-specific Ionic Liquid-mediated Facile Synthesis of 1,3,5-Triaryltriazines by Cyclotrimerization of Imines and Their Biological Evaluation

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Chemistry Letters 43(4), 521-523, 2014
… The synthesized compounds were subjected for in vitro antitubercular activity against Mycobacterium tuberculosis H37Rv strain using the Löwenstein–Jensen medium. …
NAID 130004868026