WordNet
- a substance that exerts some force or effect
- a businessman who buys or sells for another in exchange for a commission (同)factor, broker
- any agent or representative of a federal agency or bureau (同)federal agent
- a representative who acts on behalf of other persons or organizations
- an active and efficient cause; capable of producing a certain effect; "their research uncovered new disease agents"
- how long something has existed; "it was replaced because of its age"
- a time of life (usually defined in years) at which some particular qualification or power arises; "she was now of school age"; "tall for his eld" (同)eld
- begin to seem older; get older; "The death of his wife caused him to age fast"
- make older; "The death of his child aged him tremendously"
PrepTutorEJDIC
- 『代理人』;周旋人 / 働き(作用)を起こすもの;作用物,薬剤 / (政府機関,特にFBI,CIAなどの)部員,機関員
- 〈U〉(一般に)『年齢』,寿命;〈C〉(個々の)『年齢』,年 / 〈U〉成年(おとなとしての資格・権利を得る年齢;通例18または21歳) / 〈U〉『老齢』;《集合的に》老人たち / 〈U〉(人生の)『一時期』;〈C〉世代(generation) / 〈U〉〈C〉《しばしばA-》(歴史上の)『時代』 / 〈C〉《話》長い間 / 年をとる,ふける;〈物が〉古くなる / 〈年〉'を'とらせる;〈物〉'を'古びさせる
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/05/06 22:39:20」(JST)
[Wiki en表示]
An antitrichomonal agent is an antiprotozoal agent that acts on trichomonas parasites.[1]
Examples include:[2]
- furazolidone
- nifuratel
- nimorazole
- ornidazole
- tinidazole
- usnic acid
References
- ^ Antitrichomonal Agents at the US National Library of Medicine Medical Subject Headings (MeSH)
- ^ MeSH list of agents 82000994
Antiparasitics – antiprotozoal agents – Chromalveolate antiparasitics (P01)
|
|
Alveo-
late |
Apicom-
plexa |
Conoidasida/
(Coccidiostats) |
Cryptosporidiosis |
- thiazolide (nitazoxanide)
|
|
Isosporiasis |
- trimethoprim/sulfamethoxazole#
|
|
Toxoplasmosis |
- pyrimethamine
- sulfadiazine
|
|
|
Aconoidasida |
Malaria |
Individual
agents |
Hemozoin
inhibitors |
aminoquinolines |
- (4-): amodiaquine#
- chloroquine#
- Tafenoquine
- (8-): primaquine#
- pamaquine
|
|
4-methanolquinolines |
- mefloquine#
- quinine#
- quinidine
|
|
Other |
|
|
|
Antifolates |
DHFR inhibitors
(antifols) |
- proguanil#
- chlorproguanil
|
|
Sulfonamides |
- sulfadoxine
- sulfamethoxypyrazine
|
|
Coformulation |
- sulfadoxine/pyrimethamine (SP)#
|
|
|
Sesquiterpene
lactones |
- artemether#
- artesunate#
- dihydroartemisinin
- artemotil
- artemisinin
|
|
Other |
- atovaquone (with proguanil as Malarone)
- tetracycline
- doxycycline#
- clindamycin
- pyronaridine
- piperaquine
|
|
|
Combi-
nations |
Fixed-dose (coformulated) ACTs |
- artemether/lumefantrine#
- artesunate/amodiaquine (ASAQ)
- artesunate/mefloquine (ASMQ)
- dihydroartemisinin/piperaquine
- artesunate/pyronaridine
- arterolane/piperaquine
|
|
Other combinations
(not co-formulated) |
- artesunate/SP
- artesunate/mefloquine
- quinine/tetracycline
- quinine/doxycycline
- quinine/clindamycin
|
|
|
|
Babesiosis |
|
|
|
|
Cilio-
phora |
- Balantidiasis: Tetracycline
|
|
|
Hetero-
kont |
- Blastocystosis: Metronidazole
|
|
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
|
|
UpToDate Contents
全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.
English Journal
- A Review of Evidence-Based Care of Symptomatic Trichomoniasis and Asymptomatic Trichomonas vaginalis Infections.
- Meites E1, Gaydos CA2, Hobbs MM3, Kissinger P4, Nyirjesy P5, Schwebke JR6, Secor WE7, Sobel JD8, Workowski KA9.
- Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.Clin Infect Dis.2015 Dec 15;61 Suppl 8:S837-48. doi: 10.1093/cid/civ738.
- Trichomonas vaginalis is the most prevalent nonviral sexually transmitted infection, affecting an estimated 3.7 million women and men in the United States. Health disparities are prominent in the epidemiology of this infection, which affects 11% of women aged ≥40 years and a disproportionately hig
- PMID 26602621
- Adenosine/guanosine preferring nucleoside ribohydrolase is a distinct, druggable antitrichomonal target.
- Beck S1, Muellers SN1, Benzie AL1, Parkin DW1, Stockman BJ2.
- Bioorganic & medicinal chemistry letters.Bioorg Med Chem Lett.2015 Nov 15;25(22):5036-9. doi: 10.1016/j.bmcl.2015.10.030. Epub 2015 Oct 22.
- Nucleoside salvage pathway enzymes used by Trichomonas vaginalis are distinct from the pathway involved in activation of existing 5-nitroimidazole drugs. They thus represent excellent targets for developing novel, mechanism-based antitrichomonal agents. The purine-specific adenosine/guanosine prefer
- PMID 26592812
- A new pharmacological effect of levornidazole: Inhibition of NLRP3 inflammasome activation.
- Wang X1, Wang S1, Hu C1, Chen W1, Shen Y1, Wu X2, Sun Y3, Xu Q4.
- Biochemical pharmacology.Biochem Pharmacol.2015 Sep 15;97(2):178-88. doi: 10.1016/j.bcp.2015.06.030. Epub 2015 Jul 23.
- Levornidazole, which was originally used to inhibit anaerobic and protozoal infections, is currently known to possess a novel pharmacological effect. In this study, we investigated the possible modulation by levornidazole of NOD-like receptor protein 3 (NLRP3) inflammasome-mediated IL-1β and IL-18
- PMID 26212544
Japanese Journal
- Un agent trichomonacide: Le (thenoyl-2')-amino-2 nitro-5 thiazole C8H5O3N3S2. II. Structure cristalline et moleculaire d'une nouvelle variete monoclinique solvatee par le dimethylformamide.
- 1-(5-Nitro-2-thiazolyl)homopiperazine誘導体の合成および抗トリコモナス性(ノート)
Related Links
- An antitrichomonal agent is an antiprotozoal agent that acts upon on trichomonas parasites. Examples include: furazolidone · nifuratel · nimorazole ... Antiparasitics – antiprotozoal agents – Chromalveolate antiparasitics (P01). Alveo- late ...
- 1: Antitrichomonal Agents Agents used to treat trichomonas infections. Year introduced: 1972(1966) Subheadings: administration and dosage adverse effects analysis antagonists and inhibitors biosynthesis blood chemical synthesis chemistry ...
★リンクテーブル★
[★]
- 代行者、代理人。代理業者
- 政府職員、官吏
- ある後位をする人、ある作用をするもの。動員、動力因、作用因。(文法)動作主。科学的変化を起こさせるもの、薬品、~剤。病原体
- 関
- agonist、agonistic、attorney、delegate、drug、etiologic agent、fomes、fomites、mediator、pathogen、pathogenic、pharmaceutical preparation、vector、vehicle
[★]
- 関
- aged、ageing、aging、year old