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- 1. エボラウイルス病の治療および予防 treatment and prevention of ebola virus disease
- 2. リポ蛋白aと心血管疾患 lipoprotein a and cardiovascular disease
- 3. クローン病の内科的マネージメントにおける試験研究治療 investigational therapies in the medical management of crohn disease
- 4. 原発性免疫不全症に対する遺伝子治療 gene therapy for primary immunodeficiency
- 5. 直接作用型経口抗凝固剤：用量および副作用 direct oral anticoagulants dosing and adverse effects
English Journal
- A molecular nanodevice for targeted degradation of mRNA during protein synthesis.
- Lee KH1, Min SE1, Kim H2, Lee SG2, Kim DM1.
- Scientific reports.Sci Rep.2016 Feb 9;6:20733. doi: 10.1038/srep20733.
- RNase H is an endonuclease that catalyzes the cleavage of RNA. Because it only acts on RNA in RNA:DNA hybrids, RNase H can be used for targeted degradation of RNA when used in combination with antisense oligodeoxyribonucleotides (ASODNs) designed against a specific sequence of the target RNA. In thi
- PMID 26857021
- Cross-Linking Antisense Oligodeoxyribonucleotides with a Photoresponsive α-Chloroaldehyde Moiety for RNA Point Mutations.
- Sugihara Y1, Nakata Y1, Yamayoshi A2,3, Murakami A4, Kobori A1.
- The Journal of organic chemistry.J Org Chem.2016 Feb 5;81(3):981-6. doi: 10.1021/acs.joc.5b02573. Epub 2016 Jan 28.
- Because point mutations in GTPase-coding genes have been reported to be responsible for the transformation of cells, anticancer reagents that react effectively and sequence selectively with target RNAs having a point mutation are highly desired. In this study, we developed novel photo-cross-linking
- PMID 26788869
- M2b Monocytes Provoke Bacterial Pneumonia and Gut Bacteria-Associated Sepsis in Alcoholics.
- Tsuchimoto Y1, Asai A1, Tsuda Y1, Ito I2, Nishiguchi T2, Garcia MC2, Suzuki S3, Kobayashi M2, Higuchi K1, Suzuki F4.
- Journal of immunology (Baltimore, Md. : 1950).J Immunol.2015 Dec 1;195(11):5169-77. doi: 10.4049/jimmunol.1501369. Epub 2015 Nov 2.
- Chronic alcohol consumption markedly impairs host antibacterial defense against opportunistic infections. γ-irradiated NOD-SCID IL-2Rγ(null) mice inoculated with nonalcoholic PBMCs (control PBMC chimeras) resisted Klebsiella pneumonia and gut bacteria-associated sepsis, whereas the chimeras create
- PMID 26525287
Japanese Journal
- Significant and prolonged antisense effect of a multifunctional envelope-type nano device encapsulating antisense oligodeoxynucleotide
- Journal of Pharmacy and Pharmacology 58(4), 431-437, 2006-04
- NAID 120000954675
- Midkine antisense oligodeoxyribonucleotide inhibits renal damage induced by ischemic reperfusion
- Kidney Int. 67, 1330-1339, 2005
- NAID 30014592067
- 5位置換ピリミジンヌクレオシドを含むオリゴヌクレオチドの合成とその性質
- 有機合成化学協会誌 : JOURNAL OF Synthetic Organic Chemistry JAPAN 62(12), 1238-1248, 2004-12-01
- NAID 10014119789
Related Links
- To elucidate the role of CREB in the growth of submandibular gland, the effect of an antisense oligodeoxyribonucleotide (ODN) targeting CREB was examined in the organ culture system of neonatal rat submandibular gland. In the ...
- Kidney International aims to inform the renal researcher and practicing nephrologists on all aspects of renal research. Clinical and basic renal research, commentaries, The Renal Consult, Nephrology sans Frontieres ...
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★リンクテーブル★
| リンク元 | 「アンチセンスODN」「アンチセンスオリゴデオキシリボヌクレオチド」 |
| 関連記事 | 「oligodeoxyribonucleotide」「antisense」 |