antigen receptors

WordNet

any substance (as a toxin or enzyme) that stimulates an immune response in the body (especially the production of antibodies)
a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response

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1. T細胞受容体の遺伝学 t cell receptor genetics
2. T細胞受容体シグナル伝達 t cell receptor signaling
3. Sézary症候群の臨床症状、病理学的特徴、および診断 clinical presentation pathologic features and diagnosis of sezary syndrome
4. 免疫不全症を引き起こすCD3／T細胞受容体複合体疾患 cd3 t cell receptor complex disorders causing immunodeficiency
5. 適応細胞性免疫応答 the adaptive cellular immune response

As we age: Does slippage of quality control in the immune system lead to collateral damage?

Müller L1, Pawelec G2.
Ageing research reviews.Ageing Res Rev.2015 Sep;23(Pt A):116-23. doi: 10.1016/j.arr.2015.01.005. Epub 2015 Feb 9.
The vertebrate adaptive immune system is remarkable for its possession of a very broad range of antigen receptors imbuing the system with exquisite specificity, in addition to the phagocytic and inflammatory cells of the innate system shared with invertebrates. This system requires strict control bo
PMID 25676139

Ding CB1, Yu WN1, Feng JH2, Luo JM1.
Molecular medicine reports.Mol Med Rep.2015 Sep;12(3):4007-14. doi: 10.3892/mmr.2015.3951. Epub 2015 Jun 17.
The docking proteins of the Grb-associated binder (Gab) family transduce cellular signals between receptors and intracellular downstream effectors, and provide a platform for protein‑protein interactions. Gab2, a key member of the Gab family of proteins, is involved in the amplification and integr
PMID 26095858

Natural killer cell heterogeneity: cellular dysfunction and significance in HIV-1 immuno-pathogenesis.

Ansari AW1, Ahmad F, Meyer-Olson D, Kamarulzaman A, Jacobs R, Schmidt RE.
Cellular and molecular life sciences : CMLS.Cell Mol Life Sci.2015 Aug;72(16):3037-49. doi: 10.1007/s00018-015-1911-5. Epub 2015 May 5.
Natural killer (NK) cells are innate immune effectors that provide first line of defence against viruses. Human NK cells are heterogeneous in nature, and their functions rely on a dynamic balance between germ-line-encoded activating and inhibitory receptors. HIV-1 infection results in altered NK cel
PMID 25939268

Mucosal-Associated Invariant T Cell Is a Potential Marker to Distinguish Fibromyalgia Syndrome from Arthritis

Sugimoto Chie,Konno Takahiko,Wakao Rika,Fujita Hiroko,Fujita Hiroyoshi,Wakao Hiroshi
PLOS ONE 10(4), e0121124, 2015-04-09
… The percentage of mucosal-associated invariant T (MAIT) cells in PBMCs and the mean fluorescent intensity (MFI) of cell surface antigen expression in MAIT cells were analyzed. … Among the cell surface antigens in MAIT cells, three chemokine receptors, CCR4, CCR7, and CXCR1, a natural killer (NK) receptor, NKp80, a signaling lymphocyte associated molecule (SLAM) family, CD150, a degrunulation marker, CD107a, and a coreceptor, CD8 beta emerged as potential biomarkers for FMS to distinguish from HD. …
NAID 120005611266

八木淳二
東京女子医科大学雑誌 85(1), 1-8, 2015-02-25
我々の免疫システムは、自然免疫と獲得免疫からなる。自然免疫は、貪食細胞による微生物の排除など生体防御の第一線で働く。近年、自然免疫に携わる細胞の分子パターン認識受容体による病原体認識の分子基盤が急速に明かされつつある。自然免疫に引き続く獲得免疫においては、T細胞とB細胞クローンの発現する抗原受容体による精緻な抗原認識が行われる。しかし、獲得免疫のシステムでは自己と非自己の区別は不完全であり、自己免 …
NAID 110009883329