WordNet

a substance that exerts some force or effect
a businessman who buys or sells for another in exchange for a commission (同)factor, broker
any agent or representative of a federal agency or bureau (同)federal agent
a representative who acts on behalf of other persons or organizations
an active and efficient cause; capable of producing a certain effect; "their research uncovered new disease agents"
how long something has existed; "it was replaced because of its age"
a time of life (usually defined in years) at which some particular qualification or power arises; "she was now of school age"; "tall for his eld" (同)eld
begin to seem older; get older; "The death of his wife caused him to age fast"
make older; "The death of his child aged him tremendously"
a drug used to treat or prevent convulsions (as in epilepsy) (同)anticonvulsant_drug, antiepileptic, antiepileptic_drug

PrepTutorEJDIC

『代理人』;周旋人 / 働き(作用)を起こすもの;作用物,薬剤 / (政府機関,特にFBI,CIAなどの)部員,機関員
〈U〉(一般に)『年齢』,寿命;〈C〉(個々の)『年齢』,年 / 〈U〉成年(おとなとしての資格・権利を得る年齢;通例18または21歳) / 〈U〉『老齢』;《集合的に》老人たち / 〈U〉(人生の)『一時期』;〈C〉世代(generation) / 〈U〉〈C〉《しばしばA-》(歴史上の)『時代』 / 〈C〉《話》長い間 / 年をとる,ふける;〈物が〉古くなる / 〈年〉'を'とらせる;〈物〉'を'古びさせる

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Miller C1, Bauer MS.
Current psychiatry reports.Curr Psychiatry Rep.2014 Nov;16(11):499. doi: 10.1007/s11920-014-0499-z.
Bipolar disorder is associated with high mortality, and people with this disorder on average may die 10-20 years earlier than the general population. This excess and premature mortality continues to occur despite a large and expanding selection of treatment options dating back to lithium and now in
PMID 25194314

Vannucchi G1, Masi G2, Toni C3, Dell׳Osso L1, Erfurth A4, Perugi G5.
Journal of affective disorders.J Affect Disord.2014 Oct 15;168C:151-160. doi: 10.1016/j.jad.2014.06.042. Epub 2014 Jul 8.
BACKGROUND: Asperger׳s Syndrome (AS) is a neurodevelopmental disorder included in the Autism Spectrum (ASD). The current literature shows growing evidence of a high rate of comorbidity between AS and other psychiatric disorders, particularly Bipolar Disorder (BD). We reviewed available epidemiologi
PMID 25046741

Ontogenic profile of seizures evoked by the beta-carboline DMCM (methyl-6,7-dimethoxy-4-ethyl-β-carboline-3-carboxylate) in rats.

Kulick C1, Gutherz S1, Kondratyev A2, Forcelli PA3.
European journal of pharmacology.Eur J Pharmacol.2014 Oct 5;740:662-8. doi: 10.1016/j.ejphar.2014.06.012. Epub 2014 Jun 23.
The beta-carboline, methyl-6,7-dimethoxy-4-ethyl-β-carboline-3-carboxylate (DMCM), is a potent chemoconvulsant. While it has been utilized in adult rodents, it has not been previously examined for effects across postnatal development. DMCM is a negative allosteric modulator of benzodiazepine-sensit
PMID 24967532

Anticonvulsant Activity and Toxicity Evaluation of CuII and ZnII Metal Complexes Derived from Triazole-Quinoline Ligands

Kulkarni Naveen Vasudev,Budagumpi Srinivasa,Kurdekar Gurunath Suresh [他],Revankar Vidyanand Krishna,Didagi Suresh
Chemical and Pharmaceutical Bulletin 58(12), 1569-1575, 2010
… The compound C3 has exhibited promising anticonvulsant activity towards the electroshock induced seizures in Wistar rats and possesses low toxicity, providing a high safety profile. …
NAID 130000405681

Solution-Phase Parallel Synthesis of Novel 1, 2, 3, 4-Tetrahydroisoquinolin-1-ones as Anticonvulsant Agents

Gitto Rosaria,Francica Eleonora,De Sarro Giovambattista [他],SCICCHITANO Francesca,CHIMIRRI Alba
Chemical & pharmaceutical bulletin 56(2), 181-184, 2008-02-01
… Following our previous studies in the field of anticonvulsant agents, we planned a one-pot solution-phase parallel synthesis (SPPS) of a small library of new 1, 2, 3, 4-tetrahydroisoquinoline derivatives. …
NAID 110006570595

Cheng Jen-Kun,Chiou Lih-Chu
Journal of pharmacological sciences 100(5), 471-486, 2006-05-15
… Gabapentin, a γ-aminobutyric acid (GABA) analogue anticonvulsant, is also an effective analgesic agent in neuropathic and inflammatory, but not acute, pain systemically and intrathecally. …
NAID 10018239057