anterior pituitary hormone

• 下垂体前葉ホルモン

WordNet

1. of or near the head end or toward the front plane of a body
2. earlier in time (同)prior
3. of or relating to the pituitary gland; "pituitary hormone"
4. the master gland of the endocrine system; located at the base of the brain (同)pituitary_gland, pituitary body, hypophysis
5. the secretion of an endocrine gland that is transmitted by the blood to the tissue on which it has a specific effect (同)endocrine, internal_secretion

PrepTutorEJDIC

1. (場所などが)前の,前部の;(…より)前に位置する《+『to』+『名』》 / (時・事件などが)以前の,先の;(…より)前の《+『to』+『名』》
2. 脳下垂体の(から得られた) / =pituitary gland
3. ホルモン

UpToDate Contents

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• 1. 下垂体機能低下症の臨床症状 clinical manifestations of hypopituitarism
• 2. 視床下部下垂体軸 hypothalamic pituitary axis
• 3. 甲状腺ホルモンに対する感受性の傷害 impaired sensitivity to thyroid hormone
• 4. 小児における成長ホルモン欠乏症の治療 treatment of growth hormone deficiency in children
• 5. 成長ホルモンの生理学 physiology of growth hormone

English Journal

• Store-operated Ca entry and Ca responses to hypothalamic releasing hormones in anterior pituitary cells from Orai1-/- and heptaTRPC knockout mice.

• Núñez L, Bird GS, Hernando-Pérez E, Pérez-Riesgo E, Putney JW, Villalobos C.
• Biochimica et biophysica acta. Molecular cell research. 2019 Jul;1866(7)1124-1136.
• Store operated Ca entry (SOCE) is the most important Ca entry pathway in non-excitable cells. However, SOCE can also play a pivotal role in excitable cells such as anterior pituitary (AP) cells. The AP gland contains five different cell types that release six major AP hormones controlling most of th
• PMID 30452936

• Differential and temporal expression of corticotropin releasing hormone and its receptors in the nucleus of the hippocampal commissure and paraventricular nucleus during the stress response in chickens (Gallus gallus).

• Kadhim HJ, Kang SW, Kuenzel WJ.
• Brain research. 2019 Jul;1714()1-7.
• Recently, in addition to the paraventricular nucleus (PVN), the nucleus of the hippocampal commissure (NHpC) have been proposed to regulate stress in birds due to the discovery of corticotropin releasing hormone (CRH) neurons in the NHpC. Expression of CRH, CRHR1, CRHR2 and glucocorticoid receptors
• PMID 30772274

• Clinical and biochemical characteristics of high-intensity functional training (HIFT) and overtraining syndrome: findings from the EROS study (The EROS-HIFT).

• Cadegiani FA, Kater CE, Gazola M.
• Journal of sports sciences. 2019 Jun;37(11)1296-1307.
• The metabolic and hormonal consequences of high-intensity functional training regimens such as CrossFit® (CF) are unclear. Little is known about the triggers and clinical and biochemical features of CF-related overtraining syndrome (OTS). The EROS study compared endocrine and metabolic responses, a
• PMID 30786846

Japanese Journal

• A homozygous splice site ROBO1 mutation in a patient with a novel syndrome with combined pituitary hormone deficiency

• Dateki Sumito,Watanabe Satoshi,Mishima Hiroyuki,Shirakawa Toshihiko,Morikawa Minoru,Kinoshita Eiichi,Yoshiura Koh-ichiro,Moriuchi Hiroyuki
• Journal of Human Genetics 64(4), 341-346, 2019-01-28
• … The genetic causes of combined pituitary hormone deficiency remain elusive in most patients. … Recently, incompletely penetrant heterozygous mutations in ROBO1 have been described in patients with pituitary stalk interruption syndrome. …
• NAID 120006583201

• 自己免疫性膵炎に併発した下垂体機能低下の1例

• 池田 千咲,上野 義之,牧野 直彦,安藤 嘉章,松田 暁子,柿﨑 泰明,石澤 哲也,齋藤 吉彦,山川 光徳,亀田 亘
• 日本消化器病学会雑誌 116(2), 168-176, 2019
• <p>64歳男性．CTで膵体尾部腫脹，IgG4高値，ERPで膵管狭細像を認めた．病理所見を加え自己免疫性膵炎の診断となった．頭部MRIで下垂体茎腫大，負荷試験で下垂体前葉機能低下を認めたが，ステロイド治療により改善傾向を認めた．IgG4関連下垂体炎はまれで，症状も非特異的であり疾患を想起しづらいが，下垂体機能低下が潜在している可能性がある．画像検査で下垂体炎が疑われた際は機能評価も行う …
• NAID 130007596512

• イピリムマブ投与後に生じた下垂体炎の 1 例

• 清水 友理,種村 篤,壽 順久,沖田 朋憲,向井 康祐,片山 一朗
• 皮膚の科学 17(5), 260-264, 2018
• <p><b>70</b>歳代，男性。悪性黒色腫 <b>Stage 4 </b>に対してイピリムマブ投与中。来院 <b>3 </b>週間前に <b>3 </b>投目のイピリムマブを投与し，投与数日後から嘔気，食欲不振，全身倦怠感が出現した。近医で補液されるも改善なく当科を受診された。来院時，低 …
• NAID 130007628053

Related Links

• anterior pituitary hormone - definition of anterior pituitary ...

Anterior Pituitary Hormone Hypersecretion (APHH) Findings Percentage of APHH Hormone Population Indicators Growth 20% More common in men; gigantism in hormone children, acromegaly in adult: hands, feet and lower jaw are ...

• Anterior Pituitary - Free nursing ceus - $29.95/30 hrs - free ...

Some of these anterior pituitary hormones induce other glands to secrete their hormones. The rise in blood levels of the hormones produced by the final target glands (for example, the ovary or thyroid) inhibits the release of anterior ...

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★リンクテーブル★

リンク元	「下垂体前葉ホルモン」
関連記事	「anterior」「pituitary」

「下垂体前葉ホルモン」

　　[★]

英

anterior pituitary hormone

関

下垂体前葉、下垂体、下垂体ホルモン、ホルモン

分泌されるホルモン

• 単純ペプチドホルモン

• 成長ホルモン(growth hormone, GH)
• 副腎皮質刺激ホルモン(adrenocorticotropic hormone, ACTH)
• プロラクチン(prolactin)

• 糖タンパク質ホルモン

• 甲状腺刺激ホルモン(thyroid-stimulating hormone,TSH)
• 卵胞刺激ホルモン(follicle-stimulating hormone,FSH)
• 黄体形成ホルモン(luteinizing hormone, LH)

GOO. chapter 55

名称		構造	分泌細胞	下垂体前葉細胞 全細胞に対する 産生細胞の割合	染色性		サブユニット	残基数 (aa.)	分子量 (kDa)	その他
成長ホルモン	GH	ペプチド	somatotroph	40-50%	好酸性		1	191	22
プロラクチン	PRL		mammotroph	10-25%	好酸性		1	199	23
副腎皮質刺激ホルモン	ACTH		corticotroph	0.1	好塩基性	嫌色素性	1	39	4.5	POMC由来
甲状腺刺激ホルモン	TSH	糖タンパク	thyrotroph	0.05	好塩基性		2	α: 92, β:118	28	αサブユニットは共通
卵胞刺激ホルモン	FSH		gonadotroph	10-15%	好塩基性		2	α: 92, β:111	32.6
黄体形成ホルモン	LH				好塩基性		2	α: 92, β:121	29.4

HIM.2196

Table 333-1 Anterior Pituitary Hormone Expression and Regulation
Cell	corticotrope	somatotrope	lactotrope	thyrotrope	gonadotrope
Tissue-specific transcription factor	T-Pit	Prop-1, Pit-1	Prop-1, Pit-1	Prop-1, Pit-1, TEF	SF-1, DAX-1
Fetal appearance	6 weeks	8 weeks	12 weeks	12 weeks	12 weeks
Hormone	POMC	GH	PRL	TSH	FSH LH
Chromosomal locus	2p	17q	6	－6q; －1p	－11p; －19q
Protein	ポリペプチド			糖タンパク
Amino acids	266 (ACTH 1–39)	191	199	211	210 204
Stimulators	CRH, AVP, gp-130 cytokines	GHRH, ghrelin, bromocriptine(1)	estrogen, TRH, VIP	TRH	GnRH, activins, estrogen
Inhibitors	glucocorticoids	somatostatin, IGF-I	dopamine	T3, T4, dopamine, somatostatin, glucocorticoids	sex steroids, inhibin
Target gland	adrenal	liver, other tissues	breast, other tissues	thyroid	ovary, testis
Trophic effect	steroid production	IGF-I production, growth induction, insulin antagonism	milk production	T4 synthesis and secretion	sex steroid production, follicle growth, germ cell maturation

(1):QB.D-253

「anterior」

　　[★]

• adj.

• 前側の、前の

関

anterioris、anteriorly、before、fore、former、pre、prior

　 　 　

「pituitary」

　　[★]

• adj.

• 下垂体の

関

hypophyses、hypophysis、pituitary gland