Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/05/08 19:51:52」(JST)

wiki en

Anonychia is the absence of nails, a rare anomaly, which may be the result of a congenital ectodermal defect, ichthyosis, severe infection, severe allergic contact dermatitis, self-inflicted trauma, Raynaud phenomenon, lichen planus, epidermolysis bullosa, or severe exfoliative diseases.^[1]^:784

Congenital form

This is rare and is usually due to mutations in the R-spondin 4 (RSPO4) gene which is located on the short arm of chromosome 20 (20p13).^[2] Clinically it is manifest by the absence (anonychia) or hypoplasia (hyponuchia) of finger- and/or toenails.

References

^ James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. ISBN 0-7216-2921-0.
^ Khan TN, Klar J, Nawaz S, Jameel M, Tariq M, Malik NA, Baig SM, Dahl N (2012) Novel missense mutation in the RSPO4 gene in congenital hyponychia and evidence for a polymorphic initiation codon (p.M1I). BMC Med Genet 13(1):120

This Condition of the skin appendages article is a stub. You can help Wikipedia by expanding it.

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. 爪疾患の概要 overview of nail disorders
2. 移植片対宿主病（GVHD）の皮膚症状 cutaneous manifestations of graft versus host disease gvhd
3. サルコイドーシスの皮膚症状 cutaneous manifestations of sarcoidosis
4. 膿疱性乾癬：病因、臨床症状、および診断 pustular psoriasis pathogenesis clinical manifestations and diagnosis
5. 表皮水疱症の疫学、病因、分類、および臨床的特徴 epidemiology pathogenesis classification and clinical features of epidermolysis bullosa

English Journal

SYNDROME IN QUESTION.

Chiacchio ND1, Jasso-Olivares JC2, Chiacchio NG1, Jacinto JA1, Restrepo MV1.
Anais brasileiros de dermatologia.An Bras Dermatol.2015 May-Jun;90(3):423-5. doi: 10.1590/abd1806-4841.20153395. Epub 2015 Jun 1.
The Iso-Kikuchi Syndrome is a rare condition characterized by nail dysplasia involving the index fingers, including micronychia, polyonychia, anonychia, irregular lunula, malalignment and hemionychogryphosis. On the antero-posterior image, radiologic examination reveals a narrowing of the distal pha
PMID 26131880

Congenital constriction ring of limbs in subjects with history of maternal substance use.

Malik S1, Lal K1, Fatima NG1, Samo A2, Haque S1.
Journal of the College of Physicians and Surgeons--Pakistan : JCPSP.J Coll Physicians Surg Pak.2015 May;25(5):383-5. doi: 05.2015/JCPSP.383385.
Congenital Constriction Ring (CCR) is a rare malformation which manifests itself in the form of ring-like constrictive bands. Due to its heterogeneous nature, its etiology remains unclear. Here, we present a series of seven independent individuals afflicted with CCR, which primarily involved the dig
PMID 26008671

Congenital anonychia.

Qureshi A1, Wong KY2, Grant I3.
The Journal of hand surgery, European volume.J Hand Surg Eur Vol.2015 Apr 16. pii: 1753193415583245. [Epub ahead of print]
PMID 25881976

Japanese Journal

The gene encoding R-spondin 4 (RSPO4), a secreted protein implicated in Wnt signaling, is mutated in inherited anonychia

Nat. Genet. 38, 1245-1247, 2006
NAID 80018911420

Twenty Nail Anonychia Due to Lichen Planus

Journal of dermatology 31(2), 146-147, 2004-02-01
NAID 10016258490

Anonychiaを伴った歯肉線維腫症について

日本歯周病学会会誌 16(1), 355-358, 1974-02
NAID 110006203942

Related Pictures

Nails at Saint Louis University - StudyBlue Anonychia (ontbrekende nagels) Anonychia - Congenital Malformations Browser Scar Tissue And Im Nail - Nail Disorders - Arthritis Research Hands of Children: Fingernail Disorders in Childhood! 2/2 | Finger nails