WordNet
- a living organism characterized by voluntary movement (同)animate being, beast, brute, creature, fauna
- marked by the appetites and passions of the body; "animal instincts"; "carnal knowledge"; "fleshly desire"; "a sensual delight in eating"; "music is the only sensual pleasure without vice" (同)carnal, fleshly, sensual
- of or relating to the milk-giving gland of the female
- (Jungian psychology) the inner self (not the external persona) that is in touch with the unconscious
PrepTutorEJDIC
- (植物に対して)『動物』 / (人間以外の)『動物』,けだもの / (魚・鳥などに対して)哺乳動物(mammal) / けだもの(野獣)のような人 / (比較変化なし)《名詞の前にのみ用いて》動物の,動物性の,動物質の / (知的・精神的に対して)動物的な;肉欲的な
- (体内にできる)新生物;腫瘍(しゅよう)
- 乳房の
UpToDate Contents
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- 1. 成人における乳腺炎およびその他の乳房の皮膚障害 mastitis and other skin disorders of the breast in adults
- 2. 小児および思春期における乳房腫瘤の概要 overview of breast masses in children and adolescents
- 3. 陥没乳頭 nipple inversion
- 4. 幼児、小児、および思春期における乳腺炎および乳房膿瘍 mastitis and breast abscess in infants children and adolescents
- 5. 授乳および離乳の一般的問題 common problems of breastfeeding and weaning
English Journal
- Canine Mammary Tumors: A Review and Consensus of Standard Guidelines on Epithelial and Myoepithelial Phenotype Markers, HER2, and Hormone Receptor Assessment Using Immunohistochemistry.
- Peña L, Gama A, Goldschmidt MH, Abadie J, Benazzi C, Castagnaro M, Díez L, Gärtner F, Hellmén E, Kiupel M, Millán Y, Miller MA, Nguyen F, Poli A, Sarli G, Zappulli V, Mulas JM.Author information Department of Animal Medicine, Surgery and Pathology, Veterinary School, Carretera de la Coruña s/n, Ciudad Universitaria, 28040 Madrid, Spain. Email: laurape@vet.ucm.es.AbstractAlthough there have been several studies on the use of immunohistochemical biomarkers of canine mammary tumors (CMTs), the results are difficult to compare. This article provides guidelines on the most useful immunohistochemical markers to standardize their use and understand how outcomes are measured, thus ensuring reproducibility of results. We have reviewed the biomarkers of canine mammary epithelial and myoepithelial cells and identified those biomarkers that are most useful and those biomarkers for invasion and lymph node micrometastatic disease. A 10% threshold for positive reaction for most of these markers is recommended. Guidelines on immunolabeling for HER2, estrogen receptors (ERs), and progesterone receptors (PRs) are provided along with the specific recommendations for interpretation of the results for each of these biomarkers in CMTs. Only 3+ HER2-positive tumors should be considered positive, as found in human breast cancer. The lack of any known response to adjuvant endocrine therapy of ER- and PR-positive CMTs prevents the use of the biological positive/negative threshold used in human breast cancer. Immunohistochemistry results of ER and PR in CMTs should be reported as the sum of the percentage of positive cells and the intensity of immunolabeling (Allred score). Incorporation of these recommendations in future studies, either prospective or retrospective, will provide a mechanism for the direct comparison of studies and will help to determine whether these biomarkers have prognostic significance. Finally, these biomarkers may ascertain the most appropriate treatment(s) for canine malignant mammary neoplasms.
- Veterinary pathology.Vet Pathol.2014 Jan;51(1):127-45. doi: 10.1177/0300985813509388. Epub 2013 Nov 13.
- Although there have been several studies on the use of immunohistochemical biomarkers of canine mammary tumors (CMTs), the results are difficult to compare. This article provides guidelines on the most useful immunohistochemical markers to standardize their use and understand how outcomes are measur
- PMID 24227007
- Local thyroid renin-angiotensin system in experimental breast cancer.
- Carrera-González MP, Ramírez-Expósito MJ, Mayas MD, García MJ, Martínez-Martos JM.Author information Experimental and Clinical Physiopathology Research Group, Department of Health Sciences, Faculty of Experimental and Health Sciences, University of Jaén, Jaén, Spain. Electronic address: pcarrera@ujaen.es.AbstractAn association between breast cancer and thyroid dysfunction exists although the underlying mechanisms remain to be elucidated. Numerous studies have characterized the role of thyroid hormones in controlling the synthesis and secretion of renin-angiotensin system (RAS) components, but little information is available on the putative role of the local RAS on thyroid function.
- Life sciences.Life Sci.2013 Dec 18;93(25-26):1004-9. doi: 10.1016/j.lfs.2013.10.018. Epub 2013 Oct 29.
- An association between breast cancer and thyroid dysfunction exists although the underlying mechanisms remain to be elucidated. Numerous studies have characterized the role of thyroid hormones in controlling the synthesis and secretion of renin-angiotensin system (RAS) components, but little informa
- PMID 24177601
- Peripheral TGF-β1 signaling is a critical event in bone cancer-induced hyperalgesia in rodents.
- Xu Q, Zhang XM, Duan KZ, Gu XY, Han M, Liu BL, Zhao ZQ, Zhang YQ.Author information Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, 200032, China.AbstractPain is the most common symptom of bone cancer. TGF-β, a major bone-derived growth factor, is largely released by osteoclast bone resorption during the progression of bone cancer and contributes to proliferation, angiogenesis, immunosuppression, invasion, and metastasis. Here, we further show that TGF-β1 is critical for bone cancer-induced pain sensitization. We found that, after the progression of bone cancer, TGF-β1 was highly expressed in tumor-bearing bone, and the expression of its receptors, TGFβRI and TGFβRII, was significantly increased in the DRG in a rat model of bone cancer pain that is based on intratibia inoculation of Walker 256 mammary gland carcinoma cells. The blockade of TGF-β receptors by the TGFβRI antagonist SD-208 robustly suppressed bone cancer-induced thermal hyperalgesia on post-tumor day 14 (PTD 14). Peripheral injection of TGF-β1 directly induced thermal hyperalgesia in intact rats and wide-type mice, but not in Trpv1(-/-) mice. Whole-cell patch-clamp recordings from DRG neurons showed that transient receptor potential vanilloid (TRPV1) sensitivity was significantly enhanced on PTD 14. Extracellular application of TGF-β1 significantly potentiated TRPV1 currents and increased [Ca(2+)]i in DRG neurons. Pharmacological studies revealed that the TGF-β1 sensitization of TRPV1 and the induction of thermal hyperalgesia required the TGF-βR-mediated Smad-independent PKCε and TGF-β activating kinase 1-p38 pathways. These findings suggest that TGF-β1 signaling contributes to bone cancer pain via the upregulation and sensitization of TRPV1 in primary sensory neurons and that therapeutic targeting of TGF-β1 may ameliorate the bone cancer pain in advanced cancer.
- The Journal of neuroscience : the official journal of the Society for Neuroscience.J Neurosci.2013 Dec 4;33(49):19099-111. doi: 10.1523/JNEUROSCI.4852-12.2013.
- Pain is the most common symptom of bone cancer. TGF-β, a major bone-derived growth factor, is largely released by osteoclast bone resorption during the progression of bone cancer and contributes to proliferation, angiogenesis, immunosuppression, invasion, and metastasis. Here, we further show that
- PMID 24305807
Japanese Journal
- ウサギの子宮疾患３１１例に関する疫学的検討
- 佐藤 英実,内海 美和,高久 ゆうき,鶴岡 学,中西 真紀子,斉藤 久美子
- 動物臨床医学 18(2), 25-29, 2009
- 開腹手術により子宮の異常を確認したウサギの311例を回顧的に調査・検討した。主たる臨床症状は陰部出血が72.7%でもっとも多く，次いで乳腺異常(9.6%)，腹囲膨満(7.7%)，腹部腫瘤の触知(6.8%)等であったことから，雌ウサギにこれらの症状が認められた場合には子宮疾患を鑑別診断に入れる必要のあることが示された。病理組織学的検査に供した76例では腺癌が24例(31.6%)ともっとも多かった。病 …
- NAID 130004935146
- ウサギの子宮腫よう３６例
- 強矢 治,寺尾 順子,志賀 聡子,中西 真紀子,田川 雅代,森 千秋,斉藤 久美子
- 獣医麻酔外科学雑誌 33(1), 1-7, 2002
- 動物病院に来院し, 子宮腫瘍と診断された36例のウサギについて検討した。主訴として陰部からの出血が最も多く, また食欲不振や乳腺の腫脹なども多く認められた。診断には, 尿の血液反応, 腹部の触診と乳腺の観察, そして腹部超音波検査が有用であった。腫瘍は腺腫や腺癌が多数を占め, これらは比較的若齢のうちに発生することも多かった。術後短期間の転帰は腫瘍の種類によるよりもむしろ術前の全身状態によるところ …
- NAID 130004184957
Related Links
- LSDシソーラス: 動物乳腺腫瘍 Animal Mammary Neoplasm 動物乳腺腫瘍 (Animal Mammary Neoplasm) を Google Scholar, Entrez, Google, Wikipedia で検索 同義語（異表記）： ・Animal Mammary Carcinoma ・動物乳癌 ...
- Animal Mammary Neoplasm,Animal Mammary Neoplasms,Mammary Neoplasm, Animal,Neoplasm, Animal Mammary,Neoplasms, Animal Mammary,Neoplasms, Mammary,Mammary Neoplasms,Mammary Neoplasm,Neoplasm ...
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★リンクテーブル★
| リンク元 | 「mammary neoplasm」「動物乳癌」「動物乳腺腫瘍」 |
| 関連記事 | 「neoplasm」「mammary neoplasm」「animal」「mammary」 |
「mammary neoplasm」
「動物乳癌」
「動物乳腺腫瘍」
「neoplasm」
- n.
「mammary neoplasm」
「animal」
- n.
- adj.
- 動物性の
「mammary」
- 乳房の、乳腺の