WordNet

any disease of the blood vessels or lymph ducts

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/08/07 22:09:50」(JST)

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Angiopathy is the generic term for a disease of the blood vessels (arteries, veins, and capillaries).^[1] The best known and most prevalent angiopathy is diabetic angiopathy, a common complication of chronic diabetes.

Classification

By caliber

There are two types of angiopathy: macroangiopathy and microangiopathy.

In macroangiopathy, atherosclerosis and a resultant blood clot forms on the large blood vessels, sticks to the vessel walls, and blocks the flow of blood. Macroangiopathy may cause other complications, such as ischemic heart disease, stroke and peripheral vascular disease which contributes to the diabetic foot ulcers and the risk of amputation.

In microangiopathy, the walls of the smaller blood vessels become so thick and weak that they bleed, leak protein, and slow the flow of blood through the body. The decrease of blood flow through stenosis or clot formation impairs the flow of oxygen to cells and biological tissues (called ischemia) and leads to cellular death (necrosis and gangrene, which in turn may require amputation). Thus, tissues which are very sensitive to oxygen levels, such as the retina, develop microangiopathy and may cause blindness (so-called proliferative diabetic retinopathy). Damage to nerve cells may cause peripheral neuropathy, and to kidney cells, diabetic nephropathy (Kimmelstiel-Wilson syndrome).

By condition

It is also possible to classify angiopathy by the associated condition:

Diabetic angiopathy
Congophilic angiopathy

References

^ "angiopathy" at Dorland's Medical Dictionary

External links

Skin care guide

UpToDate Contents

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1. 脳アミロイドアンギオパチー cerebral amyloid angiopathy
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English Journal

Vascular protection of salicin on IL-1β-induced endothelial inflammatory response and damages in retinal endothelial cells.

Song Y, Tian X, Wang X, Feng H.
Artificial cells, nanomedicine, and biotechnology. 2019 Dec;47(1)1995-2002.
Retinal endothelial cells (RECs) are involved in many ocular diseases such as age-related macular degeneration (AMD) and diabetic retinopathy. Salicin is the major ingredient of willow bark extract, and it has been shown to be a potent anti-inflammatory agent. We aim to explore whether salicin has a
PMID 31106593

The antagonist of P2Y11 receptor NF157 ameliorates oxidized LDL-induced vascular endothelial inflammation.

Kuang Y, Liu H, Guo S, Wang Y, Zhang H, Qiao Y.
Artificial cells, nanomedicine, and biotechnology. 2019 Dec;47(1)1839-1845.
Atherosclerosis is the chronic inflammatory disease, and inflammation-elicited endothelial activation is an early event in the development of atherosclerosis. The P2Y11 receptor is a purinergic receptor and a member of the P2 family of G coupled protein which has been shown to modulate vascular func
PMID 31066305

Comparative characterization of mesenchymal stem cells from human dental pulp and adipose tissue for bone regeneration potential.

Jin Q, Yuan K, Lin W, Niu C, Ma R, Huang Z.
Artificial cells, nanomedicine, and biotechnology. 2019 Dec;47(1)1577-1584.
Bone tissue engineering is an area of regenerative medicine that attempts to repair bone defects. Seed cells such as dental pulp stem cells (DPSCs) and adipose tissue-derived stem cells (ADSCs) are two of the most well-characterized cells for bone regeneration because their use involves few ethical
PMID 31027424

Japanese Journal

Partial Identification of Amyloid-β Degrading Activity in Human Serum

Mikawa Ryuta,Okuno Alato,Yoshimi Tatsuya,Watanabe Atsushi,Maruyama Mitsuo,Takikawa Osamu
Nagoya Journal of Medical Science 81(1), 55-64, 2019-02
… The major hallmarks of Alzheimer's disease (AD) are the extracellular accumulation of pathological amyloid beta (Aβ) in the brain parenchyma and Aβ deposition in cerebral blood walls (cerebral amyloid angiopathy; …
NAID 120006583841

脳腫瘍や中枢神経感染症との鑑別を要したcerebral amyloid angiopathy related inflammation の1 例

谷将星,山下晋,長谷川洋,宮原淳一,長尾紀昭,菊井祥二,縄田昌浩,竹島多賀夫,富永紳介
Neuro-Oncologyの進歩 26(1), 12-18, 2019
… <p>We report a rare case of cerebral amyloid angiopathy-related inflammation. … Brain biopsy of the lesion showed vascular amyloid deposition in the leptomeningeal and parenchymal vessels with perivascular inflammation and abundant multi-nuclear giant cells, which suggested a diagnosis of cerebral amyloid angiopathy-related inflammation. …
NAID 130007679300

脳アミロイドアンギオパチー関連小血管病変とアルツハイマー病

池田将樹
脳卒中 41(1), 40-44, 2019
… が脳内に蓄積し，認知機能低下を来す進行性の神経変性疾患である．AD患者や高齢者では，髄膜および大脳皮質の小型から中型の動脈壁に Aβが脳血管に蓄積する脳アミロイドアンギオパチー（cerebral amyloid angiopathy: CAA）が頻繁にみられる．CAAはADの認知症を増悪させる因子として知られていたが，脳画像技術の進歩に伴い，多様な病態が明らかになりつつある．一方，CAA関連炎症［CAA-related inflammation（RI）］は近年注目 …
NAID 130007557023

「血管障害」

　　[★]

英: angiopathy, vascular disorder
同？: 脈管障害、血管障害性、脈管症、血管症

「脈管障害」

　　[★]

英: vasculopathy、angiopathy
関: 血管障害、脈管症、血管症

「angiopathic」

　　[★]

血管障害性の、血管障害の

関: angiopathy、vascular disorder

「脈管症」

　　[★]

英: angiopathy
関: 血管障害、脈管障害、血管症

「血管症」

　　[★]

英: angiopathy
関: 血管障害、脈管障害、脈管症

「congophilic angiopathy」

　　[★]

コンゴーレッド親和性血管障害、コンゴレッド親和性血管障害

関: cerebral amyloid angiopathy

「diabetic macroangiopathy」

　　[★]

糖尿病性大血管障害、糖尿病大血管障害

「amyloid angiopathy」

　　[★]

同: アミロイド・アンギオパチー

[1] "angiopathy" at Dorland's Medical Dictionary

リンク元	「血管障害」「脈管障害」「angiopathic」「脈管症」「血管症」
拡張検索	「congophilic angiopathy」「diabetic macroangiopathy」「amyloid angiopathy」

匿名

検索

案内

案内

angiopathy