WordNet

relating to anemia or suffering from anemia (同)anaemic
lacking vigor or energy; "an anemic attempt to hit the baseball" (同)anaemic
localized necrosis resulting from obstruction of the blood supply (同)infarction

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2012/07/27 22:01:08」(JST)

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Anemic infarcts (also called white infarcts or pale infarcts) are white or pale infarcts caused by arterial occlusions, and are usually seen in the heart, kidney and spleen. These are referred to as "white" because of the lack of hemorrhaging and limited red blood cells accumulation, (compare to Hemorrhagic infarct). The tissues most likely to be affected are solid organs which limit the amount of hemorrhage that can seep into the area of ischemic necrosis from adjoining capillary beds. The organs typically include single blood supply (no dual arterial blood supply or anastomoses). The infarct generally results grossly in a wedge shaped area of necrosis with the apex closest to the occlusion and the base at the periphery of the organ. The margins will become better defined with time with a narrow rim of congestion attributable to inflammation at the edge of the lesion. ^[1] Relatively few extravasated red cells are lysed so the resulting hemosiderosis is limited and results in a progressively more pale area of infarction with time. Ischemic coagulative necrosis results and fibrosis of the affected area develops from the reparative response beginning at the preserved margins and working its way inwards. One exception to coagulative necrosis is the brain, which undergoes liquefactive necrosis in response to infarction.

References

^ Robbins Basic Pathology

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1. 貧血を有する成人患者に対するアプローチ approach to the adult patient with anemia
2. 貧血を有する小児に対するアプローチ approach to the child with anemia
3. 成人における溶血性貧血の診断へのアプローチ approach to the diagnosis of hemolytic anemia in the adult
4. 小児における溶血性貧血の概要 overview of hemolytic anemias in children
5. 赤血球産生低下による貧血 anemias due to decreased red cell production

English Journal

Outcomes of Protocol-Driven Care of Critically Ill Severely Anemic Patients for Whom Blood Transfusion Is Not an Option.

Shander A1, Javidroozi M, Gianatiempo C, Gandhi N, Lui J, Califano F, Kaufman M, Naqvi S, Syed F, Aregbeyen O.
Critical care medicine.Crit Care Med.2016 Jan 20. [Epub ahead of print]
OBJECTIVE: To compare the outcomes of severely anemic critically ill patients for whom transfusion is not an option ("bloodless" patients) with transfused patients.DESIGN: Cohort study with propensity score matching.SETTING: ICU of a referral center.PATIENTS: One hundred seventy-eight bloodless and
PMID 26807684

Cardiovascular Morbidity and Pure Red Cell Aplasia Associated With Epoetin Theta Therapy in Patients With Chronic Kidney Disease: A Prospective, Noninterventional, Multicenter Cohort Study.

Lammerich A1, Balcke P2, Bias P3, Mangold S3, Wiesholzer M2.
Clinical therapeutics.Clin Ther.2015 Dec 18. pii: S0149-2918(15)01302-8. doi: 10.1016/j.clinthera.2015.11.018. [Epub ahead of print]
PURPOSE: The European Medicines Agency recommends limiting the hemoglobin (Hb) concentration to 10 to 12 g/dL in adults with chronic kidney disease (CKD) receiving erythropoiesis-stimulating agents such as epoetin theta. This postauthorization study assessed the incidence and intensity of cardiovasc
PMID 26708119

The Association of Anemia and Its Severity with Cardiac Outcomes and Mortality After Total Knee Arthroplasty in Noncardiac Patients.

Chamieh JS1, Tamim HM2, Masrouha KZ1, Saghieh SS1, Al-Taki MM1.
The Journal of arthroplasty.J Arthroplasty.2015 Nov 10. pii: S0883-5403(15)00973-0. doi: 10.1016/j.arth.2015.10.035. [Epub ahead of print]
BACKGROUND: The purpose of this study is to assess whether an association exists between preoperative anemia and postoperative cardiac events or death in patients undergoing unilateral primary total knee arthroplasty (TKA) with no prior cardiac history.METHODS: Data from the 2008-2012 American Colle
PMID 26689615