androgen receptor

出典: meddic


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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/12/09 19:04:43」(JST)

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2017/12/18 23:02:18」(JST)

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  • Atorvastatin induces autophagy in prostate cancer PC3 cells through activation of LC3 transcription.
  • Toepfer N, Childress C, Parikh A, Rukstalis D, Yang W.SourceGeisinger Clinic; Danville, PA USA.
  • Cancer biology & therapy.Cancer Biol Ther.2011 Oct 15;12(8). [Epub ahead of print]
  • Our previous studies have demonstrated that atorvastatin induces autophagy in the androgen receptor negative prostate cancer PC3 cells through inhibition of geranylgeranyl biosynthesis [Parikh et al., Prostate. 70(9): 971-981 (2010)]. This study attempts to elucidate the molecular mechanism underlyi
  • PMID 21768780
  • Inability of NCoR/SMRT to repress androgen receptor transcriptional activity in prostate cancer cell lines.
  • Laschak M, Bechtel M, Spindler KD, Hessenauer A.SourceInstitute of General Zoology and Endocrinology, Ulm University, Albert-Einstein-Allee 11, D-89069 Ulm, Germany.
  • International journal of molecular medicine.Int J Mol Med.2011 Oct;28(4):645-51. doi: 10.3892/ijmm.2011.735. Epub 2011 Jun 27.
  • The molecular mechanisms leading to castration-resistant prostate cancer (CRPC) are poorly understood. Among several mechanisms leading to CRPC growth a dysregulation of androgen receptor (AR) co-regulators (i.e. up-regulation of co-activators or down-regulation of co-repressors) is discussed. There
  • PMID 21720703


  • Epigenetic setting for long-term expression of estrogen receptor α and androgen receptor in cells.
  • Imamura Takuya
  • Hormones and behavior 59(3), 345-352, 2011-03
  • … Epigenetic regulation of the nuclear estrogen and androgen receptors, ER and AR, constitutes the molecular basis for the long-lasting effects of sex steroids on gene expression in cells. … The effects prevail at hundreds of gene loci in the proximity of estrogen- and androgen-responsive elements and many more such loci through intra- and even inter-chromosomal level regulation. … The factors affecting the DNA methylation of the ERα and AR genes in cells include estrogen and androgen. …
  • NAID 120002970855
  • アンドロゲン受容体の標的ネットワークの同定--ゲノム医学的手法による系統的なアンドロゲン受容体下流因子の同定 (第1土曜特集 エネルギー代謝転写因子ネットワークと生活習慣病) -- (転写因子ネットワークシステムの新しい俯瞰)
  • 高山 賢一,井上 聡
  • 医学のあゆみ 237(6), 646-652, 2011-05-07
  • NAID 40018778620


The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor that is activated by binding of either of the androgenic hormones testosterone or dihydrotestosterone in ...


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androgen receptor AR




androgen receptor


  [★] 受容体

WordNet   license wordnet

「a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response」

PrepTutorEJDIC   license prepejdic

「=sense organ / 受信装置」


  [★] アンドロゲン

WordNet   license wordnet

「male sex hormone that is produced in the testes and responsible for typical male sexual characteristics」
androgenic hormone

PrepTutorEJDIC   license prepejdic