- 関
- amyloid beta、amyloid beta-protein
WordNet
- to remain unmolested, undisturbed, or uninterrupted -- used only in infinitive form; "let her be"
- work in a specific place, with a specific subject, or in a specific function; "He is a herpetologist"; "She is our resident philosopher" (同)follow
- have life, be alive; "Our great leader is no more"; "My grandfather lived until the end of war" (同)live
- be identical to; be someone or something; "The president of the company is John Smith"; "This is my house"
- happen, occur, take place; "I lost my wallet; this was during the visit to my parents house"; "There were two hundred people at his funeral"; "There was a lot of noise in the kitchen"
- have the quality of being; (copula, used with an adjective or a predicate noun); "John is rich"; "This is not a good answer"
- occupy a certain position or area; be somewhere; "Where is my umbrella?" "The toolshed is in the back"; "What is behind this behavior?"
- spend or use time; "I may be an hour"
- stake on the outcome of an issue; "I bet $100 on that new horse"; "She played all her money on the dark horse" (同)wager, play
- the act of gambling; "he did it on a bet" (同)wager
- maintain with or as if with a bet; "I bet she will be there!" (同)wager
- second in order of importance; "the candidate, considered a beta male, was perceived to be unable to lead his party to victory"
- the 2nd letter of the Greek alphabet
- preliminary or testing stage of a software or hardware product; "a beta version"; "beta software"
- (pathology) a waxy translucent complex protein resembling starch that results from degeneration of tissue
- a non-nitrogenous food substance consisting chiefly of starch; any substance resembling starch
- amide combining the amino group of one amino acid with the carboxyl group of another; usually obtained by partial hydrolysis of protein
PrepTutorEJDIC
- 《連結語として補語を伴なって…『である』,…だ,…です / 《位置・場所を表す語句を伴って》(…に)『ある』,いる(occupy a place or situation) / 〈物事が〉『存在する』,ある(exist);〈生物が〉生存する,生きている(live) / 行われる,起こる,発生する(take place, occur) / 存続する,そのままでいる(remain as before) / 《『be to』 do》 / …する予定である,…することになっている / …すべきだ / 《受動態の不定詞を伴って》…できる / 《命令》…するのだ / 《条件節に》…する意図がある / 《『if…were to』 do》…するとしたなら / 《『be』 do『ing』》《進行形》 / 《進行中の動作》…している,しつつある / 《近い未来》…しようとしている,するつもり / 《動作の反復》(いつも)…している / 《『be』+『他動詞の過去分詞』》《受動態》…される,されている / 《『be』+『自動詞の過去分詞』》《完了形》…した[状態にある]
- 『かけ』・(…との)かけ《+『with』+『名』》 / かけた物(金) / かけの対象 / 〈金・物〉'を'『かける』 / (かけ事・ゲームなどで)〈人〉‘と'『かけをする』《+『名』〈人〉+『on』+『名』》 / (…に)『かける』《+『on』(『against』)+『名』(one's do『ing』)》
- ベータ(ギリシア語アルファベットの第2文字;B,β;英語のB,b に遭当)
UpToDate Contents
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English Journal
- Alzheimer amyloid beta inhibition of Eg5/kinesin 5 reduces neurotrophin and/or transmitter receptor function.
- Ari C1, Borysov SI2, Wu J3, Padmanabhan J1, Potter H4.
- Neurobiology of aging.Neurobiol Aging.2014 Aug;35(8):1839-49. doi: 10.1016/j.neurobiolaging.2014.02.006. Epub 2014 Feb 10.
- The mechanism by which amyloid beta (Aβ) causes neuronal dysfunction and/or death in Alzheimer's disease (AD) is unclear. Previously, we showed that Aβ inhibits several microtubule-dependent kinesin motors essential for mitosis and also present in mature neurons. Here, we show that inhibition of k
- PMID 24636920
- Sleep deprivation impairs memory, tau metabolism, and synaptic integrity of a mouse model of Alzheimer's disease with plaques and tangles.
- Di Meco A1, Joshi YB1, Praticò D2.
- Neurobiology of aging.Neurobiol Aging.2014 Aug;35(8):1813-20. doi: 10.1016/j.neurobiolaging.2014.02.011. Epub 2014 Feb 15.
- Several studies have highlighted the frequency of sleep disturbances in Alzheimer's disease (AD). However, whether they are secondary to the disease or per se increase its risk remains to be fully investigated. The aim of the current investigation was to study the effect of sleep deprivation (SD) on
- PMID 24629673
- N-terminal 5-mer peptide analog P165 of amyloid precursor protein inhibits UVA-induced MMP-1 expression by suppressing the MAPK pathway in human dermal fibroblasts.
- Wang Y1, Chen H1, Wang W2, Wang R3, Liu ZL1, Zhu W4, Lian S5.
- European journal of pharmacology.Eur J Pharmacol.2014 Jul 5;734C:1-8. doi: 10.1016/j.ejphar.2014.03.028. Epub 2014 Mar 29.
- Exposure to ultraviolet (UV) radiation leads to a progressive increase in dermal damage through the degradation of collagen, which is mediated by matrix metalloproteinases (MMPs). UV radiation alters the intracellular signaling events that regulate the elaboration of MMPs. Our previous study showed
- PMID 24685639
Japanese Journal
- Suppression of Alzheimer's Disease-Related Phenotypes by Geranylgeranylacetone in Mice
- Hoshino Tatsuya,Suzuki Koichiro,Matsushima Takahide,Yamakawa Naoki,Suzuki Toshiharu,Mizushima Tohru
- Plos one 8(10), e76306, 2013-10-01
- … Amyloid-beta peptide (A beta) plays an important role in the pathogenesis of Alzheimer's disease (AD). … A beta is generated by the secretase-mediated proteolysis of beta-amyloid precursor protein (APP), and cleared by enzyme-mediated degradation and phagocytosis. … Transforming growth factor (TGF)-beta 1 stimulates this phagocytosis. …
- NAID 120005365906
- Highlighted Paper selected by Editor-in-Chief : Shuttling Protein Nucleolin Is a Microglia Receptor for Amyloid Beta Peptide 1-42
- Ozawa Daisuke,Nakamura Takashi,Koike Masanori [他]
- Biological & pharmaceutical bulletin 36(10), 1587-1593, 2013-10
- NAID 40019800736
- Shuttling Protein Nucleolin is a Microglia Receptor for Amyloid Beta Peptide 1–42
- Ozawa Daisuke,Nakamura Takashi,Koike Masanori,Hirano Kazuya,Miki Yuichi,Beppu Masatoshi
- Biological and Pharmaceutical Bulletin, 2013
- … Amyloid-beta peptide 1–42 (Aβ42) plays a key role in the neurotoxicity found in Alzheimer's disease. … While monomeric and fibril Aβ42 were phagocytosed by mouse microglial EOC2 cells, amyloid βpeptide 1–40 (Aβ40) was only weakly phagocytosed. …
- NAID 130003361542
Related Links
- 1. J Alzheimers Dis. 2010;19(1):311-23. doi: 10.3233/JAD-2010-1221. Alzheimer's disease and the amyloid-beta peptide. Murphy MP(1), LeVine H 3rd. Author information: (1)Department of Molecular and ...
- Peptides , Amyloid Peptides; Beta-Amyloid (Aß) peptides, made up of long, insoluble ordered fibers, are glycoproteins deposited extracellularly in tissues in amyloidosis. These peptides are generated as cleavage products 39 to 43 ...
★リンクテーブル★
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- 英
- amyloid beta-protein、amyloid beta-peptide、amyloid beta
- 関
- アミロイドβタンパク、アミロイドβペプチド、アミロイドβ蛋白、βアミロイドタンパク質
[★]
- 関
- amyloid beta、amyloid beta-peptide、beta-amyloid protein
[★]
- 関
- amyloid beta-peptide、amyloid beta-protein
[★]
- 英
- amyloid beta-peptide
- 関
- アミロイドβタンパク質
[★]
- 関
- amyloid beta-peptide、amyloid beta-protein
[★]
アミロイド
- 関
- amyloid fibril、amyloid protein
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β、ベータ
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