ampicillin phthalidyl

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• 1. 腸球菌における抗菌薬耐性の機構 mechanisms of antibiotic resistance in enterococci
• 2. β-ラクタマーゼ阻害剤、カルバペネム系、およびモノバクタム系抗菌薬の併用 combination beta lactamase inhibitors carbapenems and monobactams
• 3. ペニシリン penicillins
• 4. 腸球菌感染症の治療 treatment of enterococcal infections
• 5. 正期産児および後期早産児における敗血症のマネージメントおよび転帰 management and outcome of sepsis in term and late preterm infants

English Journal

• Molecular cloning, expression and catalytic activity of a human AKR7 member of the aldo-keto reductase superfamily: evidence that the major 2-carboxybenzaldehyde reductase from human liver is a homologue of rat aflatoxin B1-aldehyde reductase.

• Ireland LS1, Harrison DJ, Neal GE, Hayes JD.
• The Biochemical journal.Biochem J.1998 May 15;332 ( Pt 1):21-34.
• The masking of charged amino or carboxy groups by N-phthalidylation and O-phthalidylation has been used to improve the absorption of many drugs, including ampicillin and 5-fluorouracil. Following absorption of such prodrugs, the phthalidyl group is hydrolysed to release 2-carboxybenzaldehyde (2-CBA)
• PMID 9576847

• The metabolism of talampicillin in rat, dog and man.

• Jeffery DJ, Jones KH, Langley PF.
• Xenobiotica; the fate of foreign compounds in biological systems.Xenobiotica.1978 Jul;8(7):419-27.
• 1. After administration of [phthalidyl-14C] talampicillin (Talpen) to rat, dog and man, radioactivity was excreted mainly in the urine (90%, 86% and 98% in rat, dog and man respectively). 2. After administration of [ampicillin-14C] talampicillin, radioactivity was excreted in the urine of rats and d
• PMID 685291

Japanese Journal

• Talampicillin Hydrochlorideにかんする細菌学的検討

• 感染症学雑誌 49(11), 697-707, 1975
• NAID 130004328442

• Talampicillinに関する薬理学的研究

• 感染症学雑誌 49(11), 681-696, 1975
• NAID 130004328441

Related Links

• glossary_biseibutsu_abc.csv

... アミノグリコシド系薬amoxicillin AMPC アモキシシリンamphotericin B AMPH-B（ AMPH）アムホテリシンB ampicillin ABPC アンピシリンampicillin phthalidyl → talampicillin amorolfine アモロルフィンapalcillin APPC（PC-904） アパルシリン arbekacin ...

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ampicillin phthalidyl

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