出典: meddic

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/04/18 11:50:48」(JST)

wiki en

[Wiki en表示]


  • Application of an LC-MS/MS method for reliable determination of amodiaquine, N-desethylamodiaquine, artesunate and dihydroartemisinin in human plasma for a bioequivalence study in healthy Indian subjects.
  • Rathod DM1, Patel KR2, Mistri HN2, Jangid AG2, Shrivastav PS3, Sanyal M4.
  • Journal of pharmaceutical and biomedical analysis.J Pharm Biomed Anal.2016 May 30;124:67-78. doi: 10.1016/j.jpba.2016.02.021. Epub 2016 Feb 22.
  • A sensitive and high throughput bioanalytical method has been developed for reliable determination of amodiaquine (AQ), N-desethylamodiaquine (DEAQ), artesunate (AS) and dihydroartemisinin (DHA) in human plasma by LC-MS/MS. The method employs a solid phase extraction procedure without an evaporation
  • PMID 26930583
  • Lopinavir/ritonavir enhanced the antimalarial activity of amodiaquine and artesunate in a mouse model of Plasmodium berghei.
  • Abiodun OO1, Gbimadee N1, Gbotosho GO1.
  • Journal of chemotherapy (Florence, Italy).J Chemother.2016 May 5:1-5. [Epub ahead of print]
  • Treatment of malaria and HIV in co-infected patients remains a challenge due to the limited information on interaction between drugs used for the treatment of the two infections. Thus, this study evaluated the interaction between lopinavir/ritonavir (LR) and artesunate (AS), amodiaquine (AQ) or a fi
  • PMID 26900802
  • Degradation of Artemisinin-Based Combination Therapies Under Tropical Conditions.
  • Hall Z1, Allan EL1, van Schalkwyk DA1, van Wyk A1, Kaur H2.
  • The American journal of tropical medicine and hygiene.Am J Trop Med Hyg.2016 May 4;94(5):993-1001. doi: 10.4269/ajtmh.15-0665. Epub 2016 Mar 7.
  • Poor quality antimalarials, including falsified, substandard, and degraded drugs, are a serious health concern in malaria-endemic countries. Guidelines are lacking on how to distinguish between substandard and degraded drugs. "Forced degradation" in an oven was carried out on three common artemisini
  • PMID 26951346


  • Comparison of the in vitro Effects of One-day Exposure to Amodiaquine and Praziquantel on Schistosoma mansoni Adult Worm Pairs
  • In vitro effects of amodiaquine on paired Schistosoma mansoni adult worms at concentrations of less than 5 μg/mL
  • The Tyrosine Kinase Inhibitor Nilotinib Selectively Inhibits CYP2C8 Activities in Human Liver Microsomes


Amodiaquine has been shown to be more effective than chloroquine in treating chloroquine-resistant Plasmodium falciparum malaria infections and may afford more protection than chloroquine when used as weekly prophylaxis. Amodiaquine ...
Amodiaquine generic is an antimalarial agent, prescribed for malaria either alone or with other medications.