WordNet

a silvery soft waxy metallic element of the alkali metal group; occurs abundantly in natural compounds (especially in salt water); burns with a yellow flame and reacts violently in water; occurs in sea water and in the mineral halite (rock salt) (同)Na, atomic number 11

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Effects of topical indomethacin, bromfenac and nepafenac on lipopolysaccharide-induced ocular inflammation.

Bucolo C1, Marrazzo G, Platania CB, Romano GL, Drago F, Salomone S.
The Journal of pharmacy and pharmacology.J Pharm Pharmacol.2014 Jul;66(7):954-60. doi: 10.1111/jphp.12224. Epub 2014 Feb 12.
OBJECTIVES: To evaluate the effects of topical non-steroidal anti-inflammatory drugs (NSAIDs) on retinal vascular leakage, and inflammatory markers in endotoxin-induced uveitis (EIU) in rats.METHODS: EIU was induced in rats by lipopolysaccharide (LPS). Topical 0.5% indomethacin, 0.09% bromfenac and
PMID 24697218

Melatonin and amfenac modulate calcium entry, apoptosis, and oxidative stress in ARPE-19 cell culture exposed to blue light irradiation (405 nm).

Argun M1, Tök L1, Uğuz AC2, Çelik Ö2, Tök ÖY1, Naziroğlu M2.
Eye (London, England).Eye (Lond).2014 Jun;28(6):752-60. doi: 10.1038/eye.2014.50. Epub 2014 Mar 7.
PURPOSE: Under conditions of oxidative stress, cell apoptosis is triggered through the mitochondrial intrinsic pathway. Increased levels of reactive oxygen species (ROS) are linked to excess cell loss and mediate the initiation of apoptosis in a diverse range of cell types. The aims of this study we
PMID 24603419

Pharmacokinetics and efficacy of topically applied nonsteroidal anti-inflammatory drugs in retinochoroidal tissues in rabbits.

Kida T1, Kozai S2, Takahashi H2, Isaka M2, Tokushige H2, Sakamoto T3.
PloS one.PLoS One.2014 May 5;9(5):e96481. doi: 10.1371/journal.pone.0096481. eCollection 2014.
PURPOSE: To evaluate the pharmacokinetics and efficacy of topically applied nonsteroidal anti-inflammatory drugs (NSAIDs) in the retinochoroidal tissues of rabbits.METHODS: The cyclooxygenase (COX) inhibitory activity of diclofenac, bromfenac, and amfenac, an active metabolite of nepafenac, were det
PMID 24796327

豊田長隆,浅田洸一,井出信次,里村一人
日本口腔科学会雑誌 59(1), 9-16, 2010
… TMD patients with TMJ pain and/or muscle pain were treated with amfenac sodium hydrate (150 mg/day) or loxoprofen sodium hydrate (180 mg/day), and the effects on TMJ pain, muscle pain, and maximum mouth opening range were examined after 7 days of administration. …
NAID 130004555739

覚道健治,石橋克禮,大浦清,岡部貞夫,木野孔司,栗田賢一,柴田考典,杉崎正志,村上賢一郎,窪寛仁
歯科薬物療法 26(2), 44-54, 2007
… In this study, we evaluated the effect of amfenac sodium on temporomandibular joint disorders with pain according to these criteria. …
NAID 130004040536

顎関節症症型別 Amfenac Sodium (Fenazox^<(R)>) と Ethy Loflazepate (Meilax^<(R)>) の併用効果について

坂本一郎,依田哲也,塚原宏泰,森田伸,小幡宏一,榎本昭二
日本口腔外科学会雑誌 41(3), 224-232, 1995-03-20
… efficacy of combined treatment with amfenac sodium (150 mg/day for 14 days) and ethyl loflazepate (2 mg/day for 14 days) was clinically evaluated in 44 patients with temporomandibular disorders in comparison with 77 patients with temporomandibular disorders who were given amfenac sodium (150 mg/day for 14 days) alone.<BR>The 121 temporomandibular disorder patients were classified into four types (I-IV) according to the criteria proposed by the Japanese Society for the …
NAID 10006610741