WordNet
- first in order of importance; "the alpha male in the group of chimpanzees"; "the alpha star in a constellation is the brightest or main star"
- the 1st letter of the Greek alphabet
- the beginning of a series or sequence; "the Alpha and Omega, the first and the last, the beginning and the end"--Revelations
- early testing stage of a software or hardware product; "alpha version"
- any high mountain
PrepTutorEJDIC
- アルファ(ギリシア語アルファベットの第1字A,α;英語のA,aに相当) / アルファ星(星座の主星)
- 高山,高峰
UpToDate Contents
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- 1. αサラセミアの病態生理pathophysiology of alpha thalassemia [show details]
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- 4. 腫瘍壊死因子α（TNF-α）阻害剤：副作用の概要tumor necrosis factor alpha inhibitors an overview of adverse effects [show details]
- 5. 腫瘍壊死因子α（TNF-α）阻害剤：悪性腫瘍のリスクtumor necrosis factor alpha inhibitors risk of malignancy [show details]
English Journal
- Slowly progressive cholangiofibrosis induced in rats by α-naphthylisothiocyanate (ANIT), with particular references to characteristics of macrophages and myofibroblasts.
- Golbar HM, Izawa T, Ichikawa C, Tanaka M, Juniantito V, Sawamoto O, Kuwamura M, Yamate J.SourceVeterinary Pathology, Graduate School of Life and Environmental Sciences, Osaka Prefecture University, 1-58 Rinku-ourai-kita, Izumisano City, Osaka 598-8531, Japan.
- Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.Exp Toxicol Pathol.2013 Jan 5. pii: S0940-2993(12)00145-5. doi: 10.1016/j.etp.2012.12.001. [Epub ahead of print]
- A progressive cholangiofibrosis was developed as an animal model in 6-week-old male F344 rats by repeated intraperitoneal injections of α-naphthylisothiocyanate (ANIT) for 19 weeks; liver samples were examined at post-first injection (PFI) weeks 3, 7, 10, 13, 16 and 19, focusing on characteristics
- PMID 23298557
- Effects of Kupffer cell depletion on acute alpha-naphthylisothiocyanate-induced liver toxicity in male mice.
- Cullen JM, Faiola B, Melich DH, Peterson RA, Jordan HL, Kimbrough CL, Prescott JS, Miller RT.SourceCollege of Veterinary Medicine, North Carolina State University, Raleigh, NC 27607, USA. john_cullen@ncsu.edu
- Toxicologic pathology.Toxicol Pathol.2013 Jan;41(1):7-17. doi: 10.1177/0192623312451160. Epub 2012 Aug 10.
- Depletion of Kupffer cells, known to modulate chemical-induced hepatocellular injury, has not been studied with regard to biliary epithelial injury. Here, the authors investigated the effect of Kupffer cell depletion by clodronate on the toxicity of alpha-naphthylisothiocyanate (ANIT), known to inju
- PMID 22886348
- Loss of A(1) adenosine receptor attenuates alpha-naphthylisothiocyanate-induced cholestatic liver injury in mice.
- Yang P, Chen P, Wang T, Zhan Y, Zhou M, Xia L, Cheng R, Guo Y, Zhu L, Zhang J.SourceCenter for Molecular Metabolism, Nanjing University of Science & Technology, Nanjing 210094, China.
- Toxicological sciences : an official journal of the Society of Toxicology.Toxicol Sci.2013 Jan;131(1):128-38. doi: 10.1093/toxsci/kfs263. Epub 2012 Sep 6.
- Cholestasis has limited therapeutic options and is associated with high morbidity and mortality. The A(1) adenosine receptor (A(1)AR) was postulated to participate in the pathogenesis of hepatic fibrosis induced by experimental extrahepatic cholestasis; however, the contribution of A(1)AR to intrahe
- PMID 22956627
Japanese Journal
- ポリアクリルアミドゲルディスク電気泳動法によるモルモットの血漿アルカリフォスファターゼ(ALP)アイソザイム分析
- 西原 義人,後藤 玄,木村 紗綾佳,岡崎 恵美,小林 淳一,畠山 和久,成田 卓二,岡室 彰,水口 浩康,枝元 洋
- 日本毒性学会学術年会 40.1(0), 2003198, 2013
- … 3) 一方，ANIT（alpha-naphthylisothiocyanate）投与による胆汁鬱滞モデルでは，肝ALPの著増と濃縮ゲル内の発色（高分子ALP）がみられた他，小腸型ALPも増加した。 …
- NAID 130004676791
- α-Naphthylisothiocyanate (ANIT) による血中甲状腺ホルモンへの影響
- 松山 恵吾,高木 信伍,殿村 優,橋本 公美,二宮 優子,近藤 千晶,塩田 里佳,上野 元伸,鳥井 幹則
- 日本毒性学会学術年会 40.1(0), 1003049, 2013
- … 【背景・目的】胆汁うっ滞性肝障害を誘発することが知られているα-Naphthylisothiocyanate (ANIT) を6週齢のSDラットに50 mg/kgで単回経口投与したところ，24時間後に血中Thyroxine (T4) 濃度の劇的な低下が認められた．本研究では，ANITによる血中T4濃度低下の機序を解明することを目的に，ANIT投与時の甲状腺ホルモンの合成・排泄に関与する因子の測定を行った．【実験方法】6週齢のSDラットにANIT 50 mg/kgを経口投与し，24時間後に …
- NAID 130004676529
- Shigyakusan extract attenuates enhanced hepatic neutrophil infiltration and oxidative stress with progression of .ALPHA.-naphthylisothiocyanate-induced liver injury in rats
- OHTA Yoshiji,KONGO-NISHIMURA Mutsumi,HAYASHI Takahiro,KITAGAWA Akira,MATSURA Tatsuya,HASHIMOTO Takashi,YAMADA Kazuo
- Journal of Traditional Medicines 25(4), 95-102, 2008
- 本研究において， 我々は漢方薬四逆散抽出液のスプレイドライ製剤 （SGS） がラットのα-ナフチルイソチオシアナート （ANIT） 惹起肝障害の進行に伴う肝臓における好中球浸潤と酸化ストレスの亢進を抑制するか否かについて調べた。 ANIT （75 mg/kg 体重） を腹腔内に単回投与したラットにおいて， 胆汁うっ滞を伴う肝障害はその投与後24時間で発症しており， またその投与後48時間では進行し …
- NAID 130004942350
Related Links
- Isocyanates and thioisocyanates, such as ALPHA-NAPHTHYLISOTHIOCYANATE, are incompatible with many classes of compounds, reacting exothermically to release toxic gases. Reactions with amines, aldehydes, alcohols ...
- alpha-naphthylisothiocyanate a compound used experimentally to produce bile duct hyperplasia. ... Disclaimer All content on this website, including dictionary, thesaurus, literature, geography, and other reference data is for ...
Related Pictures
★リンクテーブル★
| リンク元 | 「αナフチルイソチオシアン酸」「α-ナフチルイソチオシアン酸」「1-naphthylisothiocyanate」 |
| 関連記事 | 「alpha」 |
「αナフチルイソチオシアン酸」
「α-ナフチルイソチオシアン酸」
「1-naphthylisothiocyanate」
「alpha」
- 関
- alfa