WordNet

first in order of importance; "the alpha male in the group of chimpanzees"; "the alpha star in a constellation is the brightest or main star"
the 1st letter of the Greek alphabet
the beginning of a series or sequence; "the Alpha and Omega, the first and the last, the beginning and the end"--Revelations
early testing stage of a software or hardware product; "alpha version"
any high mountain

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1. 白血球増多症および好中球増多症の定義およびメカニズム definition and mechanisms of leukocytosis and neutrophilia
2. 2型糖尿病の病因 pathogenesis of type 2 diabetes mellitus
3. 移植免疫 transplantation immunobiology
4. 心不全における一酸化窒素、その他のホルモン、サイトカイン、およびケモカイン nitric oxide other hormones cytokines and chemokines in heart failure
5. A群レンサ球菌：病原性因子および発症機序 group a streptococcus virulence factors and pathogenic mechanisms

The influence of different metal-chelate conjugates of pentixafor on the CXCR4 affinity.

Poschenrieder A1, Schottelius M2, Schwaiger M3, Kessler H4, Wester HJ2.
EJNMMI research.EJNMMI Res.2016 Dec;6(1):36. doi: 10.1186/s13550-016-0193-8. Epub 2016 Apr 26.
BACKGROUND: The overexpression of the chemokine receptor 4 (CXCR4) in different epithelial, mesenchymal, and hematopoietic cancers makes CXCR4 an attractive diagnostic and therapeutic target. However, targeting the CXCR4 receptor with small cyclic pentapeptide-based radiopharmaceuticals remains chal
PMID 27112767

Protein kinase Cδ upregulation in microglia drives neuroinflammatory responses and dopaminergic neurodegeneration in experimental models of Parkinson's disease.

Gordon R1, Singh N1, Lawana V1, Ghosh A1, Harischandra DS1, Jin H1, Hogan C1, Sarkar S1, Rokad D1, Panicker N1, Anantharam V1, Kanthasamy AG1, Kanthasamy A2.
Neurobiology of disease.Neurobiol Dis.2016 Sep;93:96-114. doi: 10.1016/j.nbd.2016.04.008. Epub 2016 May 2.
Chronic microglial activation has been linked to the progressive degeneration of the nigrostriatal dopaminergic neurons evidenced in Parkinson's disease (PD) pathogenesis. The exact etiology of PD remains poorly understood. Although both oxidative stress and neuroinflammation are identified as co-co
PMID 27151770

Distinct intrathecal interleukin-17/interleukin-6 activation in anti-N-methyl-d-aspartate receptor encephalitis.

Byun JI1, Lee ST2, Moon J2, Jung KH2, Sunwoo JS3, Lim JA2, Kim TJ2, Shin YW2, Lee KJ2, Jun JS2, Lee HS2, Lee WJ2, Kim YS4, Kim S4, Jeon D5, Park KI6, Jung KY2, Kim M2, Chu K7, Lee SK8.
Journal of neuroimmunology.J Neuroimmunol.2016 Aug 15;297:141-7. doi: 10.1016/j.jneuroim.2016.05.023. Epub 2016 Jun 1.
The aim of this study was to compare serum and cerebrospinal fluid (CSF) cytokine/chemokine levels between anti-NMDAR and anti-LGI1 encephalitis patients. Samples from fourteen anti-NMDAR encephalitis patients, ten anti-LGI1 encephalitis patients, and ten controls were analyzed for the following cyt
PMID 27397087