WordNet

applicable to or common to all members of a group or set; "the play opened to universal acclaim"; "rap enjoys universal appeal among teenage boys"
(linguistics) a grammatical rule (or other linguistic feature) that is found in all languages (同)linguistic universal
(logic) a proposition that asserts something of all members of a class (同)universal proposition
a behavioral convention or pattern characteristic of all members of a particular culture or of all human beings; "some form of religion seems to be a human universal"
adapted to various purposes, sizes, forms, operations; "universal wrench", "universal chuck"; "universal screwdriver"
loss of hair (especially on the head) or loss of wool or feathers; in humans it can result from heredity or hormonal imbalance or certain diseases or drugs and treatments (chemotherapy for cancer)

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『すべての人々の』,万人共通の;全世界の / 普遍的な,一般的な,全般的な
脱毛症

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/09/04 08:27:55」(JST)

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Alopecia universalis or alopecia areata universalis is a medical condition involving rapid loss of all hair, including eyebrows and eyelashes. It is the most severe form of alopecia areata, with an incidence of .0005% (1 in 200,000).^[1]^{[unreliable medical source?]}

Causes

Alopecia universalis can occur at any age, and is currently believed to be an autoimmune disorder.^[2]

Treatment

There is no standard treatment for alopecia universalis. Spontaneous regrowth is always a possibility, even for those with 100% hair loss over many years. However, it is not possible to predict when regrowth will occur.^[3]^{[unreliable medical source?]} Many treatments have been explored, including immunomodulatory agents such as imiquimod.^[4] Tofacitinib citrate may also have benefits. In June 2014, it was reported that a 25-year-old man with almost no hair on his body grew a full head of hair, and eyebrows, eyelashes, facial, armpit and other hair, following 8 months of treatment.^[5]

References

^ http://www.rightdiagnosis.com/a/alopecia_universalis/prevalence.htm
^ Robins DN (2007). "Case reports: alopecia universalis: hair growth following initiation of simvastatin and ezetimibe therapy". Journal of drugs in dermatology : JDD 6 (9): 946–7. PMID 17941369.
^ http://www.hairlosstalk.com/alopecia/alopecia-universalis.php
^ Letada PR, Sparling JD, Norwood C (2007). "Imiquimod in the treatment of alopecia universalis". Cutis; cutaneous medicine for the practitioner 79 (2): 138–40. PMID 17388216.
^ http://boston.cbslocal.com/2014/06/19/hairless-man-grows-full-head-of-hair-in-yale-arthritis-drug-trial/

External links

Children's Alopecia Project
Charlie Villenueva & alopecia profile
National Alopecia Areata Foundation

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1. 円形脱毛症の臨床症状および診断 clinical manifestations and diagnosis of alopecia areata
2. 円形脱毛症のマネージメント management of alopecia areata
3. IPEX：免疫不全，多腺性内分泌障害、腸疾患、X連鎖 ipex immune dysregulation polyendocrinopathy enteropathy x linked
4. 患者情報：円形脱毛症（詳細） alopecia areata beyond the basics

English Journal

Alopecia Universalis Associated with Vitiligo in an 18-year-old HIV-positive Patient: Highly Active Anti-retroviral Therapy as First Choice Therapy?

Nikolic DS, Viero D, Tijé VC, Toutous-Trellu L.SourceDepartment of Dermatology and Venereology, University Hospitals, Gabrielle-Perret-Gentil 4, 1211 Geneva 14, Switzerland.
Acta dermato-venereologica.Acta Derm Venereol.2013 Jul 4. doi: 10.2340/00015555-1651. [Epub ahead of print]
Absract is missing (letter).
PMID 23824261

Alopecia Areata: Infiltration of Th17 Cells in the Dermis, Particularly around Hair Follicles.

Tanemura A, Oiso N, Nakano M, Itoi S, Kawada A, Katayama I.SourceDepartment of Dermatology, Integrated Medicine, Osaka University Graduate School of Medicine, Suita, Japan.
Dermatology (Basel, Switzerland).Dermatology.2013 Jul 4. [Epub ahead of print]
Background: The precise pathogenesis of alopecia areata remains unknown, although this disease seems to be triggered by helper T cell infiltration in hair follicles. Recent studies of psoriasis and vitiligo have demonstrated the involvement of Th17 cells. Psoriasis and vitiligo occasionally develop
PMID 23838575