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an organic compound containing only carbon and hydrogen

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炭化水素(水素と炭素のみを含む化学物の総称)

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1. 炭化水素中毒 hydrocarbon poisoning
2. 小児および思春期における吸入剤の乱用 inhalant abuse in children and adolescents
3. 局所化学熱傷 topical chemical burns
4. 頭頸部癌に対する疫学および危険因子 epidemiology and risk factors for head and neck cancer
5. 肺癌における喫煙およびその他の危険因子 cigarette smoking and other risk factors for lung cancer

English Journal

Occupational solvent exposure and risk of meningioma: results from the INTEROCC multicentre case-control study.

McLean D, Fleming S, Turner MC, Kincl L, Richardson L, Benke G, Schlehofer B, Schlaefer K, Parent ME, Hours M, Krewski D, van Tongeren M, Sadetzki S, Siemiatycki J, Cardis E.Author information Centre for Public Health Research, Massey University, , Wellington, New Zealand.AbstractOBJECTIVE: To examine associations between occupational exposure to selected organic solvents and meningioma.
Occupational and environmental medicine.Occup Environ Med.2014 Jan 28. doi: 10.1136/oemed-2013-101780. [Epub ahead of print]
OBJECTIVE: To examine associations between occupational exposure to selected organic solvents and meningioma.METHODOLOGY: A multicentre case-control study conducted in seven countries, including 1906 cases and 5565 controls. Occupational exposure to selected classes of organic solvents (aliphatic an
PMID 24474387

A concise synthesis and antimicrobial activity of a novel series of naphthylpyridine-3-carbonitrile compounds.

Kotb ER, Anwar MM, Abbas HA, Abd El-Moez SI.Author information Photochemistry Department, National Research Centre, Dokki, Giza, Cairo, Egypt.AbstractA novel series of acyclic nucleosides 2-5 and 13a-c were synthesized by utilizing 4-phenyl-6(naphthalen-2-yl)-2-oxo-1,2-dihydropridine-3-carbonitrile (1) as a key starting material. Chlorination of 1 yielded the chloro analogue 6 that was allowed to react with urea, thiourea, thiosemicarbazide and alicyclic secondary amines to produce the corresponding derivatives 7a-c and 11a-c. Further condensation of 6 with various amino acids provided the compounds 8-10, whereas hydrazinolysis of 6 yielded the hydrazinyl analogue 12 which was condensed with different isothiocyanates and acid anhydrides to afford derivatives 18-20, respectively. Upon treatment of 12 with sodium nitrite, the azide derivative 14 was obtained which was subjected to reaction with various active methylene compounds to obtain the corresponding triazolo derivatives 15-17. The structure assignment of the new compounds is based on chemicaland spectroscopic evidence. Antimicrobial evaluation of the newly synthesized derivatives was performed using ciprofloxacin and fluconazole as reference antibacterial and antifungal drugs. The most effective compounds against the tested bacterial and fungal isolates were the benzothiohydrazide compound 18b followed by the hydrazone and the phthalic anhydride derivatives 13c and 20, respectively.
Acta poloniae pharmaceutica.Acta Pol Pharm.2013 Jul-Aug;70(4):667-79.
A novel series of acyclic nucleosides 2-5 and 13a-c were synthesized by utilizing 4-phenyl-6(naphthalen-2-yl)-2-oxo-1,2-dihydropridine-3-carbonitrile (1) as a key starting material. Chlorination of 1 yielded the chloro analogue 6 that was allowed to react with urea, thiourea, thiosemicarbazide and a
PMID 23923391

Genome analysis and physiological comparison of Alicycliphilus denitrificans strains BC and K601(T.).

Oosterkamp MJ, Veuskens T, Talarico Saia F, Weelink SA, Goodwin LA, Daligault HE, Bruce DC, Detter JC, Tapia R, Han CS, Land ML, Hauser LJ, Langenhoff AA, Gerritse J, van Berkel WJ, Pieper DH, Junca H, Smidt H, Schraa G, Davids M, Schaap PJ, Plugge CM, Stams AJ.Author information Laboratory of Microbiology, Wageningen University, Wageningen, The Netherlands.AbstractThe genomes of the Betaproteobacteria Alicycliphilus denitrificans strains BC and K601(T) have been sequenced to get insight into the physiology of the two strains. Strain BC degrades benzene with chlorate as electron acceptor. The cyclohexanol-degrading denitrifying strain K601(T) is not able to use chlorate as electron acceptor, while strain BC cannot degrade cyclohexanol. The 16S rRNA sequences of strains BC and K601(T) are identical and the fatty acid methyl ester patterns of the strains are similar. Basic Local Alignment Search Tool (BLAST) analysis of predicted open reading frames of both strains showed most hits with Acidovorax sp. JS42, a bacterium that degrades nitro-aromatics. The genomes include strain-specific plasmids (pAlide201 in strain K601(T) and pAlide01 and pAlide02 in strain BC). Key genes of chlorate reduction in strain BC were located on a 120 kb megaplasmid (pAlide01), which was absent in strain K601(T). Genes involved in cyclohexanol degradation were only found in strain K601(T). Benzene and toluene are degraded via oxygenase-mediated pathways in both strains. Genes involved in the meta-cleavage pathway of catechol are present in the genomes of both strains. Strain BC also contains all genes of the ortho-cleavage pathway. The large number of mono- and dioxygenase genes in the genomes suggests that the two strains have a broader substrate range than known thus far.
PloS one.PLoS One.2013 Jun 25;8(6):e66971. doi: 10.1371/journal.pone.0066971. Print 2013.
The genomes of the Betaproteobacteria Alicycliphilus denitrificans strains BC and K601(T) have been sequenced to get insight into the physiology of the two strains. Strain BC degrades benzene with chlorate as electron acceptor. The cyclohexanol-degrading denitrifying strain K601(T) is not able to us
PMID 23825601