WordNet

characteristic of or containing alcohol; "alcoholic drinks"
a person who drinks alcohol to excess habitually (同)alky, dipsomaniac, boozer, lush, soaker, souse
addicted to alcohol; "alcoholic expatriates in Paris"- Carl Van Doren (同)alcohol-dependent
any of a series of volatile hydroxyl compounds that are made from hydrocarbons by distillation
a liquor or brew containing alcohol as the active agent; "alcohol (or drink) ruined him" (同)alcoholic drink, alcoholic_beverage, intoxicant, inebriant
a disorder (usually of unknown origin) of the heart muscle (myocardium) (同)myocardiopathy

PrepTutorEJDIC

アルコールの,アルコール性の / アルコールのはいった;アルコール漬けの / アルコール中毒の / アルコール中毒[患]者
『アルコール』,酒精 / 『アルコール飲料』,酒

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/08/28 08:41:03」(JST)

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Alcoholic cardiomyopathy is a disease in which the chronic long-term abuse of alcohol (i.e. ethanol) leads to heart failure.^[1] Alcoholic cardiomyopathy is a type of dilated cardiomyopathy. Due to the direct toxic effects of alcohol on heart muscle, the heart is unable to pump blood efficiently, leading to heart failure. It can affect other parts of the body if the heart failure is severe. It is most common in males between the ages of 35-50.

Signs and symptoms

Signs and symptoms presented by the occurrence of alcoholic cardiomyopathy are the result of the heart failing and usually occur after the disease has progressed to an advanced stage. Therefore the symptoms have a lot in common with other forms of cardiomyopathy. These symptoms can include the following:^[2]

Ankle, feet, and leg swelling
Overall swelling
Loss of appetite
Shortness of breath, especially with activity
Breathing difficulty while lying down
Fatigue, weakness, faintness
Decreased alertness or concentration
Cough containing mucus, or pink, frothy material
Decreased urine output (oliguria)
Need to urinate at night (nocturia)
Heart palpitations (rapid heart beat)
Irregular or rapid pulse

Diagnosis

Abnormal heart sounds, murmurs, ECG abnormalities, and enlarged heart on chest x-ray may lead to the diagnosis. Echocardiogram abnormalities and cardiac catheterization or angiogram to rule out coronary artery blockages, along with a history of alcohol abuse can confirm the diagnosis.

Treatment

Treatment for alcoholic cardiomyopathy involves lifestyle changes, including complete abstinence from alcohol use, a low sodium diet, and fluid restriction, as well as medications. Medications may include ACE inhibitors, beta blockers, and diuretics which are commonly used in other forms of cardiomyopathy to reduce the strain on the heart. Persons with congestive heart failure may be considered for surgical insertion of an ICD or a pacemaker which can improve heart function. In cases where the heart failure is irreversible and worsening, heart transplant may be considered.

Treatment will possibly prevent the heart from further deterioration, and the cardiomyopathy is largely reversible if complete abstinence from alcohol is maintained.

References

^ Piano MR (May 2002). "Alcoholic cardiomyopathy: incidence, clinical characteristics, and pathophysiology". Chest 121 (5): 1638–50. doi:10.1378/chest.121.5.1638. PMID 12006456.
^ [1]

UpToDate Contents

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1. アルコール性心筋症 alcoholic cardiomyopathy
2. 拡張型心筋症の原因 causes of dilated cardiomyopathy
3. 心房細動の疫学および危険因子 epidemiology of and risk factors for atrial fibrillation
4. 心筋症の定義および分類 definition and classification of the cardiomyopathies
5. 薬物誘導性ミオパシー drug induced myopathies

English Journal

Preventive effects of North American Ginseng (Panax quinquefolius) on Diabetic Retinopathy and Cardiomyopathy.

Sen S, Chen S, Wu Y, Feng B, Lui EK, Chakrabarti S.SourceDept. of Pathology, University of Western Ontario, London, Canada; Ontario Ginseng Innovation and Research Consortium, University of Western Ontario, London, Canada.
Phytotherapy research : PTR.Phytother Res.2013 Feb;27(2):290-8. doi: 10.1002/ptr.4719. Epub 2012 May 8.
Ginseng (Araliaceae) has multiple pharmacological actions because of its diverse phytochemical constituents. The aims of the present study are to evaluate the preventive effects of North American ginseng on diabetic retinopathy and cardiomyopathy and to delineate the underlying mechanisms of such ef
PMID 22566158

Inhibition of CYP2E1 attenuates chronic alcohol intake-induced myocardial contractile dysfunction and apoptosis.

Zhang RH, Gao JY, Guo HT, Scott GI, Eason AR, Wang XM, Ren J.SourceDepartment of Geriatrics, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, People's Republic of China.
Biochimica et biophysica acta.Biochim Biophys Acta.2013 Jan;1832(1):128-41. doi: 10.1016/j.bbadis.2012.08.014. Epub 2012 Sep 2.
Alcohol intake is associated with myocardial contractile dysfunction and apoptosis although the precise mechanism is unclear. This study was designed to examine the effect of the cytochrome P450 enzyme CYP2E1 inhibition on ethanol-induced cardiac dysfunction. Adult male mice were fed a 4% ethanol li
PMID 22967841

Japanese Journal

心室内変行伝導を伴う頻脈性心房細動のため歯科治療を中断したアルコール性心筋症患者の1症例

日本歯科麻酔学会雑誌 41(2), 213-214, 2013-04-15
NAID 10031163435

飲酒量の相違により障害臓器の違いが示唆されたアルコール性心筋症の1例:─アルコール量と臓器障害の関連性

心臓 45(1), 40-45, 2013
NAID 130004688677

左室内血栓を伴ったアルコール性心筋症の1手術例

日本心臓血管外科学会雑誌 42(4), 324-328, 2013
NAID 130004548475

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★リンクテーブル★

リンク元	「アルコール性心筋症」
関連記事	「alcoholic」「alcoholics」「alcohol」

「アルコール性心筋症」

Alcoholic cardiomyopathy
Classification and external resources
Specialty	cardiology
ICD-10	I42.6
ICD-9-CM	425.5
MedlinePlus	000174
eMedicine	med/286
NCI	Alcoholic cardiomyopathy
MeSH	D002310