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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/10/24 00:21:30」(JST)
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- 1. 皮膚筋炎および多発性筋炎における間質性肺疾患：臨床症状および診断 interstitial lung disease in dermatomyositis and polymyositis clinical manifestations and diagnosis
- 2. 成人における皮膚筋炎および多発性筋炎の臨床症状 clinical manifestations of dermatomyositis and polymyositis in adults
- 3. 成人における皮膚筋炎および多発性筋炎の初期治療 initial treatment of dermatomyositis and polymyositis in adults
- 4. ヘキソースリン酸側路およびグルタチオン代謝関連疾患 related disorders of the hexose monophosphate shunt and glutathione metabolism
- 5. 炎症性ミオパチーの病因 pathogenesis of inflammatory myopathies
English Journal
- Divergent Alanyl-tRNA Synthetase Genes of Vanderwaltozyma polyspora Descended from a Common Ancestor through Whole-Genome Duplication Followed by Asymmetric Evolution.
- Chang CP1, Chang CY1, Lee YH1, Lin YS2, Wang CC3.
- Molecular and cellular biology.Mol Cell Biol.2015 Jul 1;35(13):2242-53. doi: 10.1128/MCB.00018-15. Epub 2015 Apr 20.
- Cytoplasmic and mitochondrial forms of a eukaryotic aminoacyl-tRNA synthetase (aaRS) are generally encoded by two distinct nuclear genes, one of eukaryotic origin and the other of mitochondrial origin. However, in most known yeasts, only the mitochondrial-origin alanyl-tRNA synthetase (AlaRS) gene i
- PMID 25896914
- Genotype/phenotype correlations in AARS-related neuropathy in a cohort of patients from the United Kingdom and Ireland.
- Bansagi B1, Antoniadi T, Burton-Jones S, Murphy SM, McHugh J, Alexander M, Wells R, Davies J, Hilton-Jones D, Lochmüller H, Chinnery P, Horvath R.
- Journal of neurology.J Neurol.2015 Jun 2. [Epub ahead of print]
- Charcot-Marie-Tooth disease (CMT) is the most common inherited neuropathy with heterogeneous clinical presentation and genetic background. The axonal form (CMT2) is characterised by decreased action potentials indicating primary axonal damage. The underlying pathology involves axonal degeneration wh
- PMID 26032230
- A novel AARS mutation in a family with dominant myeloneuropathy.
- Motley WW1, Griffin LB1, Mademan I1, Baets J1, De Vriendt E1, De Jonghe P1, Antonellis A1, Jordanova A1, Scherer SS2.
- Neurology.Neurology.2015 May 19;84(20):2040-7. doi: 10.1212/WNL.0000000000001583. Epub 2015 Apr 22.
- OBJECTIVE: To determine the genetic cause of neurodegeneration in a family with myeloneuropathy.METHODS: We studied 5 siblings in a family with a mild, dominantly inherited neuropathy by clinical examination and electrophysiology. One patient had a sural nerve biopsy. After ruling out common genetic
- PMID 25904691
Japanese Journal
- A Hamster Temperature-Sensitive Alanyl-tRNA Synthetase Mutant Causes Degradation of Cell-Cycle Related Proteins and Apoptosis
- Wang Yonggang,Sekiguchi Takeshi,Noguchi Eishi [他],NISHIMOTO Takeharu
- The journal of biochemistry 135(1), 7-16, 2004-01-01
- NAID 10016197271
- A Hamster Temperature-Sensitive Alanyl-tRNA Synthetase Mutant Causes Degradation of Cell-Cycle Related Proteins and Apoptosis
- Wang Yonggang,Sekiguchi Takeshi,Noguchi Eishi,Nishimoto Takeharu
- The Journal of Biochemistry 135(1), 7-16, 2004
- … We have isolated a temperature-sensitive alanyl-tRNA synthetase mutant from hamster BHK21 cells, designated as is ET12. … The mutation was localized between two RNA-binding domains of alanyl-tRNA synthetase. … Thus far, we have isolated two temperature-sensitive aminoacyl-tRNA synthetase mutants from the BHK21 cell line: is BN250 and is BN269. …
- NAID 130003418123
- Kinetic parameters for tmRNA binding to alanyl-tRNA synthetase and elongation factor Tu from Escherichia coli
- BARENDS S.
- Biochemistry 39, 2652-2658, 2000
- NAID 80011804774
Related Links
- The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases, of the class II enzymes. Class II tRNA synthases evolved early in evolution and are highly conserved. This is reflected by the fact that ...
- McLaughlin et al. (2012) identified a heterozygous R329H mutation in affected members of an Australian family with CMT2N. The substitution occurs within a highly conserved residue in the tRNA-binding domain. Aminoacylation ...
Related Pictures
★リンクテーブル★
| リンク元 | 「アラニルtRNA合成酵素」「アラニルtRNAシンテターゼ」「alanine-tRNA ligase」 |
| 拡張検索 | 「phenylalanyl-tRNA synthetase」 |
| 関連記事 | 「synthetase」「alanyl」「tRNA」「tRNAs」 |
「アラニルtRNA合成酵素」
「アラニルtRNAシンテターゼ」
「alanine-tRNA ligase」
「phenylalanyl-tRNA synthetase」
フェニルアラニルtRNA合成酵素、フェニルアラニルtRNAシンテターゼ
「synthetase」
- n.
「alanyl」
アラニル、アラニンの
「tRNA」
[★] トランスファーRNA, transfer RNA, 転位RNA