WordNet

the act of putting one thing or person in the place of another: "he sent Smith in for Jones but the substitution came too late to help" (同)exchange, commutation
an event in which one thing is substituted for another; "the replacement of lost blood by a transfusion of donor blood" (同)permutation, transposition, replacement, switch
a crystalline amino acid that occurs in many proteins

PrepTutorEJDIC

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

New broadly reactive neutralizing antibodies against hepatitis B virus surface antigen.

Kucinskaite-Kodze I1, Pleckaityte M1, Bremer CM2, Seiz PL2, Zilnyte M1, Bulavaite A1, Mickiene G1, Zvirblis G1, Sasnauskas K1, Glebe D2, Zvirbliene A3.
Virus research.Virus Res.2016 Jan 4;211:209-21. doi: 10.1016/j.virusres.2015.10.024. Epub 2015 Nov 2.
Hepatitis B virus (HBV) surface antigen (HBsAg) is considered to be the most important target for the diagnosis and immune prophylaxis of HBV infection. HBsAg-specific monoclonal antibodies (MAbs) are extensively used for studying the complex structure of the HBsAg, mapping the neutralizing epitopes
PMID 26541316

PNPLA3 148M Carriers with Inflammatory Bowel Diseases Have Higher Susceptibility to Hepatic Steatosis and Higher Liver Enzymes.

Mancina RM1, Spagnuolo R, Milano M, Brogneri S, Morrone A, Cosco C, Lazzaro V, Russo C, Ferro Y, Pingitore P, Pujia A, Montalcini T, Doldo P, Garieri P, Piodi L, Caprioli F, Valenti L, Romeo S.
Inflammatory bowel diseases.Inflamm Bowel Dis.2016 Jan;22(1):134-40. doi: 10.1097/MIB.0000000000000569.
BACKGROUND: Inflammatory bowel diseases (IBD) are characterized by chronic relapsing inflammation of the gastrointestinal tract and encompass Crohn's disease and ulcerative colitis. IBD are often associated with extraintestinal manifestations affecting multiple organs including the liver. Increased
PMID 26355465

Epitope mapping of monoclonal antibody HPT-101: a study combining dynamic force spectroscopy, ELISA and molecular dynamics simulations.

Stangner T1, Angioletti-Uberti S, Knappe D, Singer D, Wagner C, Hoffmann R, Kremer F.
Physical biology.Phys Biol.2015 Dec 21;12(6):066018. doi: 10.1088/1478-3975/12/6/066018.
By combining enzyme-linked immunosorbent assay (ELISA) and optical tweezers-assisted dynamic force spectroscopy (DFS), we identify for the first time the binding epitope of the phosphorylation-specific monoclonal antibody (mAb) HPT-101 to the Alzheimer's disease relevant peptide tau[pThr231/pSer235]
PMID 26689558