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1. 血小板機能検査 platelet function testing
2. 先天性および後天性血小板機能障害 congenital and acquired disorders of platelet function
3. クロピドグレル耐性とクロピドグレル治療不奏効 clopidogrel resistance and clopidogrel treatment failure
4. アスピリンの無効および耐性 nonresponse and resistance to aspirin
5. 小児における紫斑の評価 evaluation of purpura in children

English Journal

Reduced platelet aggregation in women after intercourse: a possible role for the cyclooxygenase pathway.

Mayoral-Andrade G1,2, Pérez-Campos-Mayoral L2, Majluf-Cruz A3, Perez-Campos Mayoral E2, Perez Campos Mayoral C2, Rocha-Núñez A1, Martinez M1, Zenteno E2, Hernandez-Gonzalez L1, López Juan MG1, Pérez-Santiago AD1, Pérez-Campos E1,2,4.
Clinical and experimental pharmacology & physiology.Clin Exp Pharmacol Physiol.2017 Aug;44(8):847-853. doi: 10.1111/1440-1681.12783.
PMID 28502103

Platelet Function Testing in Patients with Acute Ischemic Stroke: An Observational Study.

Rosafio F1, Lelli N2, Mimmi S3, Vandelli L1, Bigliardi G1, Dell'Acqua ML1, Picchetto L1, Pentore R1, Ferraro D1, Trenti T2, Nichelli P1, Zini A4.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association.J Stroke Cerebrovasc Dis.2017 Aug;26(8):1864-1873. doi: 10.1016/j.jstrokecerebrovasdis.2017.04.023. Epub 2017 May 30.
PMID 28576652

Synthesis and mechanistic evaluation of novel N'-benzylidene-carbohydrazide-1H-pyrazolo[3,4-b]pyridine derivatives as non-anionic antiplatelet agents.

Lourenço AL1, Salvador RRS2, Silva LA3, Saito MS4, Mello JFR5, Cabral LM5, Rodrigues CR5, Vera MAF6, Muri EMF6, de Souza AMT2, Craik CS7, Dias LRS8, Castro HC9, Sathler PC10.
European journal of medicinal chemistry.Eur J Med Chem.2017 Jul 28;135:213-229. doi: 10.1016/j.ejmech.2017.04.023. Epub 2017 Apr 14.
PMID 28453995

Impact of CYP2C19 Polymorphism on Platelet Function Tests and Coagulation and Inflammatory Biomarkers in Patients Undergoing Percutaneous Coronary Intervention

Kaikita Koichi,Ono Takamichi,Iwashita Satomi,Nakayama Naoki,Sato Koji,Horio Eiji,Nakamura Shinichi,Tsujita Kenichi,Tayama Shinji,Hokimoto Seiji,Sakamoto Tomohiro,Nakao Koichi,Oshima Shuichi,Sugiyama Seigo,Ogawa Hisao
Journal of Atherosclerosis and Thrombosis 21(1), 64-76, 2014
… On-clopidogrel platelet aggregation (PA), measured using light transmittance aggregometry and the VerifyNow® P2Y12 system, and the platelet reactivity index (PRI) were significantly higher at all time points in the carriers than in the noncarriers (p＜0.05), whereas there were no differences in the levels of the coagulation and inflammatory biomarkers or serum hs-TnT. …
NAID 130004845456

Pharmacodynamic Effects of Cilostazol Versus Clopidogrel in Stented Patients under Proton Pump Inhibitor Co-administration: The ACCEL-PARAZOL Study

Park Yongwhi,Jung Jin Mu,Tantry Udaya S.,Kim Kyehwan,Koh Jin Sin,Park Jeong Rang,Hwang Seok-Jae,Kwak Choong Hwan,Hwang Jin-Yong,Kim Sunjoo,Gurbel Paul A.,Jeong Young-Hoon
Journal of Atherosclerosis and Thrombosis 21(11), 1121-1139, 2014
… The platelet aggregation (PA) determined using light transmittance aggregometry and the platelet reactivity index (PRI) obtained using a vasodilator-stimulated phosphoprotein phosphorylation assay were measured before randomization and at the 14-day follow-up visit. …
NAID 130004704371

Platelet Volume Indices are Associated with High Residual Platelet Reactivity after Antiplatelet Therapy in Patients Undergoing Percutaneous Coronary Intervention

Kim Yun Gi,Suh Jung-Won,Yoon Chang-Hwan,Oh Il-Young,Cho Young-Seok,Youn Tae-Jin,Chae In-Ho,Choi Dong-Ju
Journal of Atherosclerosis and Thrombosis 21(5), 445-453, 2014
… The degree of platelet aggregation induced by arachidonic acid(AA) and adenosine diphosphate(ADP) was assessed using the Multiple Electrode Platelet Aggregometry(Multiplate®, Dynabyte, Munich, Germany)(MEA) test. …
NAID 130004444731