WordNet
- a natural attraction or feeling of kinship; "an affinity for politics"; "the mysterious affinity between them"; "Jamess affinity with Sam"
- inherent resemblance between persons or things
- the force attracting atoms to each other and binding them together in a molecule; "basic dyes have an affinity for wool and silk" (同)chemical attraction
- a close connection marked by community of interests or similarity in nature or character; "found a natural affinity with the immigrants"; "felt a deep kinship with the other students"; "anthropologys kinship with the humanities" (同)kinship
- (biology) state of relationship between organisms or groups of organisms resulting in resemblance in structure or structural parts; "in anatomical structure prehistoric man shows close affinity with modern humans" (同)phylogenetic relation
- (anthropology) kinship by marriage or adoption; not a blood relationship
- (immunology) the attraction between an antigen and an antibody
PrepTutorEJDIC
- 〈C〉(人・物に対する)好み,親近感《+『for』(『to, with』)+『名』》 / 〈U〉〈C〉(2者の間の)密接な関係,類似《+『between』+『名』》;(…との)類縁《+『with』+『名』》 / 〈U〉〈C〉親和力(原子が化学反応を起こしやすい力)
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- 1. インスリン受容体の構造および機能 structure and function of the insulin receptor
- 2. ヘモグロビンの酸素親和性に関する遺伝性疾患 genetic disorders of hemoglobin oxygen affinity
- 3. 肥満細胞：表面受容体とシグナル伝達 mast cells surface receptors and signal transduction
- 4. 多発性骨髄腫における病期分類および予後研究 staging and prognostic studies in multiple myeloma
- 5. 異常ヘモグロビン症の検査室診断 laboratory diagnosis of the hemoglobinopathies
English Journal
- Pre-clinical evaluation of eight DOTA coupled gastrin-releasing peptide receptor (GRP-R) ligands for in vivo targeting of receptor-expressing tumors.
- Accardo A1, Galli F2, Mansi R3, Del Pozzo L3, Aurilio M4, Morisco A4, Ringhieri P1, Signore A2, Morelli G1, Aloj L5.
- EJNMMI research.EJNMMI Res.2016 Dec;6(1):17. doi: 10.1186/s13550-016-0175-x. Epub 2016 Feb 20.
- BACKGROUND: Overexpression of the gastrin-releasing peptide receptor (GRP-R) has been documented in several human neoplasms such as breast, prostate, and ovarian cancer. There is growing interest in developing radiolabeled peptide-based ligands toward these receptors for the purpose of in vivo imagi
- PMID 26897133
- Development of TASP0410457 (TASP457), a novel dihydroquinolinone derivative as a PET radioligand for central histamine H3 receptors.
- Koga K1,2,3, Maeda J1, Tokunaga M1, Hanyu M1, Kawamura K1, Ohmichi M2, Nakamura T2, Nagai Y1, Seki C1, Kimura Y1, Minamimoto T1, Zhang MR1, Fukumura T1, Suhara T1, Higuchi M4.
- EJNMMI research.EJNMMI Res.2016 Dec;6(1):11. doi: 10.1186/s13550-016-0170-2. Epub 2016 Feb 9.
- BACKGROUND: Histamine H3 receptor (H3R) is a potential therapeutic target of sleep- and cognition-related disorders. The purpose of the present study is to develop a novel positron emission tomography (PET) ligand for H3Rs from dihydroquinolinone derivatives, which we previously found to have high a
- PMID 26860293
- A sensitive and selective resonance Rayleigh scattering method for quick detection of avidin using affinity labeling Au nanoparticles.
- Wang Q1, Huang X1, Fu X1, Deng H1, Ma M1, Cai Z2.
- Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.Spectrochim Acta A Mol Biomol Spectrosc.2016 Jun 5;162:75-80. doi: 10.1016/j.saa.2016.02.047. Epub 2016 Mar 9.
- Avidin is a glycoprotein with antinutritional property, which should be limited in daily food. We developed an affinity biosensor system based on resonance Rayleigh scattering (RRS) and using affinity biotin labeling Au nanoparticles (AuNPs). This method was selective and sensitive for quick avidin
- PMID 26978788
Japanese Journal
- 光反応性芳香族α-アミノ酸誘導体の合成と芳香族α-アミノ酸を標的とした効率的水素-重水素交換反応
- 橋本 誠,村井 勇太
- 有機合成化学協会誌 72(4), 360-369, 2014
- … Photoaffinity labeling is one of the favorite methods for chemical biology. … The first step in this method is the construction of photophores and their modification to the associated high affinity target ligand. …
- NAID 130004548587
- 生細胞膜タンパク質の会合・内在化の可視化解析ツール：コイルドコイルラベル法
- 矢野 義明,河野 健一,大前 薫 [他],竹田 有希,松崎 紗矢香,松崎 勝巳
- YAKUGAKU ZASSHI 134(4), 501-506, 2014
- … Genetic fusion of fluorescent/luminescent proteins to a target protein for specific labeling in living cells has been widely used to investigate the intracellular trafficking and oligomerization of the proteins. … However, several limitations of fluorescent/luminescent proteins, such as considerable size, difficulty in controlling labeling ratio in multicolor labeling, can obscure true behaviors of the target proteins. …
- NAID 130003391197
- Bladder Endothelin-1 Receptor Binding of Bosentan and Ambrisentan
- Osano Ayaka,Yokoyama Yoshinari,Hayashi Hideki [他],Itoh Kunihiko,Okura Takashi,Deguchi Yoshiharu,Ito Yoshihiko,Yamada Shizuo
- Journal of Pharmacological Sciences 124(1), 86-91, 2014
- … Specific binding of [125I]ET-1 in rat bladder was saturable and of high affinity, which characterized selective labeling of bladder ET-1 receptors. … Nonlinear least squares regression analysis revealed the presence of high- and low-affinity ET-1 receptor sites for ambrisentan and CI-1020. …
- NAID 130003382632
Related Links
- Affinity label is a molecule that is similar in structure to a particular substrate for a specific enzyme. It is considered to be a class of enzyme inactivators. These molecules covalently modify active site residues in order to elucidate the structure of ...
- Affinity labeling is a strategy to modify chemically an amino acid residue within a specific ligand-binding site of an enzyme, either at the active site or at a regulatory, allosteric site. In this approach, a reagent is designed that resembles.
Related Pictures
★リンクテーブル★
| リンク元 | 「親和標識」「affinity label」「アフィニティー標識」「アフィニティーラベル」「affinity labelling」 |
| 関連記事 | 「affinity」「labeling」 |
「親和標識」
- 英
- affinity labeling、((英))affinity labelling、affinity label
- 関
- アフィニティー標識、アフィニティーラベル
「affinity label」
「アフィニティー標識」
- 英
- affinity labeling、((英))affinity labelling、affinity label
- 関
- アフィニティーラベル、親和標識
「アフィニティーラベル」
- 英
- affinity labeling、((英))affinity labelling、affinity label
- 関
- アフィニティー標識、親和標識
「affinity labelling」
「affinity」
- 固有親和力
- 例えば、抗体の一方の抗原結合部位とB細胞エピトープとの間の平衡定数で表されるような親和性を指す