advanced glycation end product

出典: meddic

  • 加齢や高血糖によって発生して病変を誘発する化合物群


advanced glycation endproduct、advanced glycosylation end productAGE

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2017/05/27 17:09:15」(JST)

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英文文献

  • Angiopoietin-1 protects the endothelial cells against advanced glycation end product injury by strengthening cell junctions and inhibiting cell apoptosis.
  • Zhao J1, Chen L, Shu B, Tang J, Zhang L, Xie J, Liu X, Xu Y, Qi S.
  • Journal of cellular physiology.J Cell Physiol.2015 Aug;230(8):1895-905. doi: 10.1002/jcp.24920.
  • Endothelial dysfunction is a major characteristic of diabetic vasculopathy. Protection of the vascular endothelium is an essential aspect of preventing and treating diabetic vascular complications. Although Angiopoietin-1 (Ang-1) is an important endothelial-specific protective factor, whether Ang-1
  • PMID 25546411
  • Using carboxyfluorescein diacetate succinimidyl ester to monitor intracellular protein glycation.
  • Boucher J1, Simard É1, Froehlich U1, D'Orléans-Juste P1, Grandbois M2.
  • Analytical biochemistry.Anal Biochem.2015 Jun 1;478:73-81. doi: 10.1016/j.ab.2015.03.017. Epub 2015 Mar 21.
  • Protein glycation is a ubiquitous process involved in vascular complications observed in diabetes. Glyoxal (GO), an intracellular reactive oxoaldehyde that is one of the most potent glycation agents, readily reacts with amines present on proteins to produce the lysine-derived adduct carboxymethyllys
  • PMID 25800564
  • Proinflammatory Proteins S100A8/S100A9 Activate NK Cells via Interaction with RAGE.
  • Narumi K1, Miyakawa R1, Ueda R1, Hashimoto H1, Yamamoto Y1, Yoshida T2, Aoki K3.
  • Journal of immunology (Baltimore, Md. : 1950).J Immunol.2015 Jun 1;194(11):5539-48. doi: 10.4049/jimmunol.1402301. Epub 2015 Apr 24.
  • S100A8/A9, a proinflammatory protein, is upregulated in inflammatory diseases, and also has a tumor-promoting activity by the recruitment of myeloid cells and tumor cell invasion. However, whether the expression of S100A8/A9 in tumors predicts a good or poor prognosis is controversial in the clinica
  • PMID 25911757

和文文献

  • Mangostanaxanthones Ⅲ and Ⅳ : advanced glycation end-product inhibitors from the pericarp of Garcinia mangostana
  • 最新研究 大豆種子エキス麹菌発酵物の抗糖化作用
  • Fragrance journal : Research & development for cosmetics, toiletries & allied industries = フレグランスジャーナル : 香粧品科学研究開発専門誌 44(9), 65-71, 2016-09
  • NAID 40020966739
  • New Isolinariins C, D and E, Flavonoid Glycosides from Linaria japonica

関連リンク

( 2 ) フランス人のメイラード(Maillard)によって、食品の加熱調理・ 貯蔵に伴う褐変反応が発見されてからおよそ100年が経つが、 生体におけるAGEs (advanced glycation end product)研究の 歴史は意外と浅い。現在、血糖 ...
Research has shown how Advanced Glycation End products are a major factor in aging and the formation of degenerative diseases like cancer, atherosclerosis, and Alzheimer’s disease. ... How Advanced Glycation End Products ...

関連画像

Diabetes and vessel wall remodelling: from  advanced glycation end-product (AGEAdvanced glycation end products and Advanced glycation end products and Advanced Glycation End-Products (AGEs For full functionality of ResearchGate it


★リンクテーブル★
リンク元終末糖化産物」「AGE」「最終糖化産物」「advanced glycosylation end product」「最終糖化反応物
拡張検索receptor for advanced glycation end products」「advanced glycation end-products
関連記事end」「advance」「advanced」「product」「ending

終末糖化産物」

  [★]

advanced glycation end product、advanced glycation endproduct、advanced glycosylation end productAGE
最終糖化反応物最終糖化産物


AGE」

  [★]


advanced glycation end product、advanced glycation endproduct、advanced glycosylation end product


最終糖化産物」

  [★]

advanced glycation end productadvanced glycosylation end product
最終糖化反応物終末糖化産物


advanced glycosylation end product」

  [★]

advanced glycation end product、advanced glycation endproduct、AGE


最終糖化反応物」

  [★]

advanced glycation end productAGE
終末糖化産物最終糖化産物


receptor for advanced glycation end products」

  [★]

RAGE


advanced glycation end-products」

  [★]

AGEs
AGEs


end」

  [★]

  • n.
  • v.
aimbrinkceasecompleteconcludecornerdistaleventuateextremitygoalobjectobjectivesideterminalterminallyterminatetermination

WordNet   license wordnet

「put an end to; "The terrible news ended our hopes that he had survived"」

WordNet   license wordnet

「a final state; "he came to a bad end"; "the so-called glorious experiment came to an inglorious end"」
destruction, death

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「the point in time at which something ends; "the end of the year"; "the ending of warranty period"」
ending

WordNet   license wordnet

「bring to an end or halt; "She ended their friendship when she found out that he had once been convicted of a crime"; "The attack on Poland terminated the relatively peaceful period after WW I"」
terminate

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「a piece of cloth that is left over after the rest has been used or sold」
remainder, remnant, oddment

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「(American football) a position on the line of scrimmage; "no one wanted to play end"」

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「the part you are expected to play; "he held up his end"」

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「the concluding parts of an event or occurrence; "the end was exciting"; "I had to miss the last of the movie"」
last, final stage

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「either extremity of something that has length; "the end of the pier"; "she knotted the end of the thread"; "they rode to the end of the line"; "the terminals of the anterior arches of the fornix"」
terminal

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「(football) the person who plays at one end of the line of scrimmage; "the end managed to hold onto the pass"」

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「a boundary marking the extremities of something; "the end of town"」

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「a final part or section; "we have given it at the end of the section since it involves the calculus"; "Start at the beginning and go on until you come to the end"」

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「one of two places from which people are communicating to each other; "the phone rang at the other end"; "both ends wrote at the same time"」

WordNet   license wordnet

「the surface at either extremity of a three-dimensional object; "one end of the box was marked `This side up''"」

PrepTutorEJDIC   license prepejdic

「(細いものの)『端』,先端《+『of』+『名』》 / (物語などの)『終り』,終結部《+『of』+『名』》 / (物事・期間の)『最後』《+『of』+『名』》;(…に)結末をつけるもの《+『to』+『名』》 / (…の)端の部分,末端部《『of』+『名』》 / 《しばしば複数形で》『目的』(purpose),目標(aim) / 《遠回しに》死,滅亡 / 《しばしば複数形で》切れ端,くず,残りもの / (事業などの)部門(part) / (フットボールで)エンド)前衛両端の選手または位置) / …‘を'『終わらせる』,終える / 〈物事が〉…‘の'終りとなる,‘を'締めくくる / 『終わる』,終了する(come to an end)」

WordNet   license wordnet

「have an end, in a temporal, spatial, or quantitative sense; either spatial or metaphorical; "the bronchioles terminate in a capillary bed"; "Your rights stop where you infringe upon the rights of other"; "My property ends by the bushes"; "The symphony ends in a pianissimo"」
stop, finish, terminate, cease

WordNet   license wordnet

「be the end of; be the last or concluding part of; "This sad scene ended the movie"」
terminate


advance」

  [★]

  • n.
  • v.
  • 進行する、進歩する、前進する、進む
advancementgoimprovenavigateproceedprogressprogressionstride

WordNet   license wordnet

「increase in price or value; "the news caused a general advance on the stock market"」
rise

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「an amount paid before it is earned」
cash advance

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「rise in rate or price; "The stock market gained 24 points today"」
gain

WordNet   license wordnet

「pay in advance; "Can you advance me some money?"」

PrepTutorEJDIC   license prepejdic

「…'を'『前進させる』,前に出す / 〈事〉'を'『進める』,促進する / (ある階級・地位などに)〈人〉'を'昇進させる《+『名』〈人〉+『to』+『名』》 / 《『advance』+『名』〈人〉+『名』〈金〉=『advance』+『名』〈金〉+『to』+『名』〈人〉》 〈人〉‘に'〈金〉'を'前払いする,融資する / 〈時間・期日〉'を'早める;〈時計〉‘の'時間を早める / (…に向かって)『前進する』,進む《+『on』(『upon, toward』)+『名』》 / (…に)昇進する《+『to』(『in』)+『名』》 / 〈事が〉進歩する,はかどる / 〈時が〉進む / 〈値段・価値が〉上がる / 〈U〉〈C〉『進むこと』,前進 / 〈U〉(…の)流れ,進行《+『of』+『名』》 / 〈U〉〈C〉(…の)進歩,発達《+『of』+『名』》 / 〈U〉〈C〉(…への)昇進,出世《+『to』+『名』》 / 〈C〉(…の)前払い,前払い金《+『on』+『名』》 / 《複数形で》(人に)言い寄ること,取り入ること《+『to』+『名』》 / 前進している / 前もっての」

WordNet   license wordnet

「situated ahead or going before; "an advance party"; "at that time the most advanced outpost was still east of the Rockies"」
advanced, in advance

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「being ahead of time or need; "gave advance warning"; "was beforehand with her report"」
beforehand

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「cause to move forward; "Can you move the car seat forward?"」
bring forward

WordNet   license wordnet

「move forward, also in the metaphorical sense; "Time marches on"」
progress, pass on, move on, march on, go on

WordNet   license wordnet

「move forward; "we have to advance clocks and watches when we travel eastward"」
set ahead

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「bring forward for consideration or acceptance; "advance an argument"」
throw out

WordNet   license wordnet

「develop further; "We are advancing technology every day"」


advanced」

  [★]

  • adj.
  • 高度な、先端的な、進行型の、後生的な
altitudehighhigh degreehigh levelhigh-gradehighly

WordNet   license wordnet

「farther along in physical or mental development; "the child''s skeletal age was classified as `advanced''"; "children in the advanced classes in elementary school read far above grade average"」

PrepTutorEJDIC   license prepejdic

「進出した,前進した / 進歩した / 上級の,高等の / (時が)進んだ,進行した」

WordNet   license wordnet

「ahead of the times; "the advanced teaching methods"; "had advanced views on the subject"; "a forward-looking corporation"; "is British industry innovative enough?"」
forward-looking, innovative, modern

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「far along in time; "a man of advanced age"; "advanced in years"; "a ripe old age"; "the ripe age of 90"」
ripe

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「ahead in development; complex or intricate; "advanced technology"; "a sophisticated electronic control system"」
sophisticated

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「(of societies) highly developed especially in technology or industry; "advanced societies"; "an advanced country technologically"」

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「at a higher level in training or knowledge or skill; "an advanced degree"; "an advanced text in physics"; "special seminars for small groups of advanced students at the University"」

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「comparatively late in a course of development; "the illness had reached an advanced stage"; "an advanced state of exhaustion"」


product」

  [★]

  • n.
accomplishmentachievementconsequenceoutcomeoutputresultresultantsequence

WordNet   license wordnet

「an artifact that has been created by someone or some process; "they improve their product every year"; "they export most of their agricultural production"」
production

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「a chemical substance formed as a result of a chemical reaction; "a product of lime and nitric acid"」

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「a consequence of someone''s efforts or of a particular set of circumstances; "skill is the product of hours of practice"; "his reaction was the product of hunger and fatigue"」

WordNet   license wordnet

「a quantity obtained by multiplication; "the product of 2 and 3 is 6"」
mathematical product

PrepTutorEJDIC   license prepejdic

「『産物』;製品 / (…の)結果,帰結《+『of』+『名』(do『ing』)》 / (数の)積 / (化学の)生成物」


ending」

  [★]

  • n.
terminalterminally

WordNet   license wordnet

「event whose occurrence ends something; "his death marked the ending of an era"; "when these final episodes are broadcast it will be the finish of the show"」
conclusion, finish

WordNet   license wordnet

「the end of a word (a suffix or inflectional ending or final morpheme); "I don''t like words that have -ism as an ending"」
termination

PrepTutorEJDIC   license prepejdic

「終り,終了;(物語・映画などの)結末 / (文の)語尾」




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