WordNet

an impairment of health or a condition of abnormal functioning
any mature animal
a fully developed person from maturity onward (同)grownup
(of animals) fully developed; "an adult animal"; "a grown woman" (同)big, full-grown, fully grown, grown, grownup
caused by or altered by or manifesting disease or pathology; "diseased tonsils"; "a morbid growth"; "pathologic tissue"; "pathological bodily processes" (同)morbid, pathologic, pathological

PrepTutorEJDIC

(体の)『病気』,疾患 / (精神・道徳などの)病気,病弊
女性の話術芸人 =diseur
『おとなの』,成人した,成熟した / 成人向きの / 『おとな』,成人
病気にかかった / 病的な,不健全な(morbid)

UpToDate Contents

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1. ウィルソン病：臨床症状、診断、および自然史 wilson disease clinical manifestations diagnosis and natural history
2. 嚢胞性線維症：肝胆道系疾患 cystic fibrosis hepatobiliary disease
3. ライム病の治療 treatment of lyme disease
4. もやもや病：病因、臨床的特徴、および診断 moyamoya disease etiology clinical features and diagnosis
5. フォックス・フォアダイス病（アポクリン汗疹） fox fordyce disease apocrine miliaria

English Journal

Tonsillectomy as a treatment for psoriasis: a review.

Wu W1, Debbaneh M, Moslehi H, Koo J, Liao W.Author information 1Department of Dermatology, Psoriasis and Skin Treatment Center, University of California, San Francisco Medical Center , San Francisco, CA , USA .AbstractPsoriasis is a chronic skin disorder that affects 1% to 3% of the general population worldwide. Streptococcal infection, especially streptococcal pharyngitis, has been shown to be a significant trigger of psoriasis in some patients, possibly by sensitizing T cells to keratin epitopes in the skin. Due to the role of the palatine tonsils as an immunological organ that may generate autoreactive T cells, tonsillectomy has been investigated as a treatment for psoriasis. Tonsillectomy originally gained acceptance in Japan as a treatment for palmoplantar pustulosis, a condition that shares features with pustular psoriasis. Subsequently, tonsillectomy has been used for the treatment of plaque psoriasis and guttate psoriasis. Recently, the first randomized, controlled clinical trial of tonsillectomy was performed. Here, we review the available evidence for the benefit of tonsillectomy as a treatment for palmoplantar pustulosis and psoriasis. We also discuss molecular studies aimed at understanding the role of tonsils in skin disease.
The Journal of dermatological treatment.J Dermatolog Treat.2014 Dec;25(6):482-6. doi: 10.3109/09546634.2013.848258. Epub 2013 Nov 27.
Psoriasis is a chronic skin disorder that affects 1% to 3% of the general population worldwide. Streptococcal infection, especially streptococcal pharyngitis, has been shown to be a significant trigger of psoriasis in some patients, possibly by sensitizing T cells to keratin epitopes in the skin. Du
PMID 24283892

Periocular photodynamic therapy for squamous intra-epidermal carcinoma.

Casie Chetty N1, Hemmant B, Skellett AM.Author information 1Department of Dermatology and.AbstractOBJECTIVES: To evaluate the response of Metvix photodynamic therapy (PDT) for the treatment of periocular Bowen's disease.
The Journal of dermatological treatment.J Dermatolog Treat.2014 Dec;25(6):516-8. doi: 10.3109/09546634.2013.849793. Epub 2013 Nov 12.
OBJECTIVES: To evaluate the response of Metvix photodynamic therapy (PDT) for the treatment of periocular Bowen's disease.METHODS: Four patients with biopsy-proven Bowen' disease were treated with Metvix PDT between November 2010 and January 2012. A detailed description of the technique used is desc
PMID 24215518

Efficacy of leukotriene receptor antagonist with anti-H1 receptor antagonist plus anti-H2 receptor antagonist for treatment of refractory chronic idiopathic urticaria.

Wan KS1, Chang YS.Author information 1Department of Pediatrics, Taipei City Hospital , Renai Branch , Taiwan and.AbstractBACKGROUND: The efficacy of the combination of leukotriene receptor antagonist (LRA) and H1 antihistamine was similar to the synergistic regimen of H1 and H2 antihistamine for treatment of chronic idiopathic urticaria (CIU). However, the effective rates of these two regimens were only 53.3% and 63.3%, respectively.
The Journal of dermatological treatment.J Dermatolog Treat.2014 Dec;25(6):459-61. doi: 10.3109/09546634.2013.849791. Epub 2013 Nov 5.
BACKGROUND: The efficacy of the combination of leukotriene receptor antagonist (LRA) and H1 antihistamine was similar to the synergistic regimen of H1 and H2 antihistamine for treatment of chronic idiopathic urticaria (CIU). However, the effective rates of these two regimens were only 53.3% and 63.3
PMID 24192062

Japanese Journal

症例コクサッキーウイルスA6による手足口病の成人5症例

髙山恵律子,山本哲久,吉崎仁胤 [他]
皮膚科の臨床 55(11), 1441-1446, 2013-11
NAID 40019873306

Management of adult patients with Philadelphia positive acute lymphoblastic leukemia (第75回日本血液学会学術集会教育講演特集号) -- (リンパ系腫瘍 : ALL/ML)

FOA Robin,VITALE Antonella,GRAMMATICO Sara [他]
臨床血液 54(10), 1828-1837, 2013-10
NAID 40019805804

SLC25A13 Gene Analysis in Citrin Deficiency: Sixteen Novel Mutations in East Asian Patients, and the Mutation Distribution in a Large Pediatric Cohort in China

Song Yuan-Zong,Zhang Zhan-Hui,Lin Wei-Xia,Zhao Xin-Jing,Deng Mei,Ma Yan-Li,Guo Li,Chen Feng-Ping,Long Xiao-Ling,He Xiang-Ling,Sunada Yoshihide,Soneda Shun,Nakatomi Akiko,Dateki Sumito,Ngu Lock-Hock,Kobayashi Keiko,Saheki Takeyori
PLoS ONE 8(9), e74544, 2013-09-19
… Background:The human SLC25A13 gene encodes citrin, the liver-type mitochondrial aspartate/glutamate carrier isoform 2 (AGC2), and SLC25A13 mutations cause citrin deficiency (CD), a disease entity that encompasses different age-dependant clinical phenotypes such as Adult-onset Citrullinemia Type II (CTLN2) and Neonatal Intrahepatic Cholestasis caused by Citrin Deficiency (NICCD). …
NAID 120005343849