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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2017/11/25 01:14:32」(JST)

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  • Inhibitory effects of p-aminohippurate and probenecid on the renal clearance of adefovir and benzylpenicillin as probe drugs for organic anion transporter (OAT) 1 and OAT3 in humans.
  • Maeda K1, Tian Y1, Fujita T2, Ikeda Y2, Kumagai Y2, Kondo T3, Tanabe K3, Nakayama H3, Horita S3, Kusuhara H1, Sugiyama Y4.
  • European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.Eur J Pharm Sci.2014 Aug 1;59C:94-103. doi: 10.1016/j.ejps.2014.04.004. Epub 2014 Apr 18.
  • Probe substrates for, and inhibitors of, specific transporters are desired to evaluate quantitatively the in vivo functions of transporters in humans. Based on published data, adefovir and benzylpenicillin were selected as organic anion transporter (OAT) 1- and OAT3-selective probe substrates, respe
  • PMID 24747579
  • The Impact of the Hepatitis B Virus Polymerase rtA181T Mutation on Replication and Drug Resistance Is Potentially Affected by Overlapping Changes in Surface Gene.
  • Ahn SH1, Park YK2, Park ES2, Kim JH3, Kim DH1, Lim KH1, Jang MS1, Choe WH3, Ko SY3, Sung IK3, Kwon SY3, Kim KH4.
  • Journal of virology.J Virol.2014 Jun 15;88(12):6805-6818. Epub 2014 Apr 2.
  • The emergence of drug-resistant hepatitis B virus (HBV) is a major problem for antiviral treatment in chronic hepatitis B infection. In this study, we analyzed the evolution of drug-resistant mutations and characterized the effects of the rtA181T and rtI233V mutations on viral replication and drug r
  • PMID 24696492
  • Generation of a human hepatoma cell line supporting efficient replication of a lamivudine resistant hepatitis B virus.
  • Zhang Y1, Zhang Y1, Kang Y1, Wang J1, Liu H1, Zhu H1, Qin Y1, Mao R1, Lin X2, Lu M3, Zhang J4.
  • Journal of virological methods.J Virol Methods.2014 Jun;201:51-6. doi: 10.1016/j.jviromet.2014.02.008. Epub 2014 Feb 28.
  • Emergence of lamivudine (LAM) resistance causes treatment failure in patients with chronic hepatitis B and compromise the efficacy of subsequent salvage therapies with other nucleot(s)ide analogs (NAs). Establishment of cell-based assays supporting LAM-resistant hepatitis B virus (HBV) replication w
  • PMID 24583110


  • 臨床室 両踵骨不全骨折を契機に診断されたアデホビルピボキシルによる骨軟化症の1例
  • アデホビルにてFanconi症候群を来たしたB型慢性肝炎の1例
  • Bone Histology of Two Cases with Osteomalacia Related to Low-dose Adefovir


Adefovir dipivoxil, previously called bis-POM PMEA, with trade names Preveon and Hepsera, is an ... Adefovir was invented in the Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic by Antonín Holý, ...






アデホビルジピボキシルアデホビルピボキシルアデフォビルピボキシル adefovir dipivoxil


  • アデニン類似体