WordNet

of critical importance and consequence; "an acute (or critical) lack of research funds"
having or demonstrating ability to recognize or draw fine distinctions; "an acute observer of politics and politicians"; "incisive comments"; "icy knifelike reasoning"; "as sharp and incisive as the stroke of a fang"; "penetrating insight"; "frequent penetrative observations" (同)discriminating, incisive, keen, knifelike, penetrating, penetrative, piercing, sharp
extremely sharp or intense; "acute pain"; "felt acute annoyance"; "intense itching and burning" (同)intense
having or experiencing a rapid onset and short but severe course; "acute appendicitis"; "the acute phase of the illness"; "acute patients"
of an angle; less than 90 degrees
relating to or caused by a virus; "viral infection"
inflammation of the liver caused by a virus or a toxin

PrepTutorEJDIC

(先の)『鋭い』,とがった / (痛み・感情などが)『激しい』,強い / (知力・感覚などが)『鋭い』,鋭敏な / (事態が)重大な / (病気が)急性の / (音が)高い,鋭い / 鋭角の
ウィルスの;ウィルスが原因の
肝[臓]炎

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Factors associated with hepatitis C virus RNA levels in early chronic infection: the InC(3) study.

Hajarizadeh B1, Grady B2, Page K3, Kim AY4, McGovern BH5,6, Cox AL7, Rice TM3, Sacks-Davis R8,9, Bruneau J10, Morris M3, Amin J1, Schinkel J11, Applegate T1, Maher L1, Hellard M8,9, Lloyd AR12, Prins M2,11, Geskus RB2,11, Dore GJ1, Grebely J1; InC3 Study Group.
Journal of viral hepatitis.J Viral Hepat.2015 Sep;22(9):708-17. doi: 10.1111/jvh.12384. Epub 2015 Jan 8.
Improved understanding of natural history of hepatitis C virus (HCV) RNA levels in chronic infection provides enhanced insights into immunopathogenesis of HCV and has implications for the clinical management of chronic HCV infection. This study assessed factors associated with HCV RNA levels during
PMID 25580520

Inhibition of hepatitis E virus replication by peptide-conjugated morpholino oligomers.

Nan Y1, Ma Z1, Kannan H1, Stein DA2, Iversen PI3, Meng XJ4, Zhang YJ5.
Antiviral research.Antiviral Res.2015 Aug;120:134-9. doi: 10.1016/j.antiviral.2015.06.006. Epub 2015 Jun 15.
Hepatitis E virus (HEV) infection is a cause of hepatitis in humans worldwide and has been associated with a case-fatality rate of up to 30% in pregnant women. Recently, persistent and chronic HEV infections have been recognized as a serious clinical problem, especially in immunocompromised individu
PMID 26086884

Hullegie SJ1, Arends JE2, Rijnders BJ1, Irving WL3, Salmon D4, Prins M5, Wensing AM6, Klenerman P7, Leblebicioglu H8, Boesecke C9, Rockstroh JK10, Hoepelman AI6.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.Clin Microbiol Infect.2015 Aug;21(8):797.e9-797.e17. doi: 10.1016/j.cmi.2015.03.026. Epub 2015 Apr 16.
Acute hepatitis C virus (HCV) infections are frequently seen worldwide in certain risk groups, with an annual incidence rate varying between 0.08% and 66%. Although this incidence is substantial, a delayed diagnosis during chronic infection is most often made in the absence of clinical symptoms in t
PMID 25892133