WordNet

of critical importance and consequence; "an acute (or critical) lack of research funds"
having or demonstrating ability to recognize or draw fine distinctions; "an acute observer of politics and politicians"; "incisive comments"; "icy knifelike reasoning"; "as sharp and incisive as the stroke of a fang"; "penetrating insight"; "frequent penetrative observations" (同)discriminating, incisive, keen, knifelike, penetrating, penetrative, piercing, sharp
extremely sharp or intense; "acute pain"; "felt acute annoyance"; "intense itching and burning" (同)intense
having or experiencing a rapid onset and short but severe course; "acute appendicitis"; "the acute phase of the illness"; "acute patients"
of an angle; less than 90 degrees
in or relating to the retina of the eye; "retinal cells"
the localized death of living cells (as from infection or the interruption of blood supply) (同)mortification, gangrene, sphacelus
the innermost light-sensitive membrane covering the back wall of the eyeball; it is continuous with the optic nerve

PrepTutorEJDIC

(先の)『鋭い』,とがった / (痛み・感情などが)『激しい』,強い / (知力・感覚などが)『鋭い』,鋭敏な / (事態が)重大な / (病気が)急性の / (音が)高い,鋭い / 鋭角の
壊疽(えそ)
(目の)網膜

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/03/25 20:31:31」(JST)

Acute retinal necrosis is a type of retinitis which can be associated with viral infections.

It was first characterized in 1971.^[1]^[2]

One study indicated an incidence of 1 per 1.6 to 2.0 million.^[3]

The exact causes are not known, but varicella zoster virus is frequently implicated,^[4] and other herpesviruses can be involved.^[5]

Treatments that have been used include foscarnet,^[6] valacyclovir and famciclovir.^[7]

^ "eMedicine - Acute Retinal Necrosis : Article by Andrew A Dahl, MD". Archived from the original on 16 February 2008. Retrieved 2008-02-05.
^ Urayama A, Yamada N, Sasaki T: Unilateral acute uveitis with retinal periarteritis and detachment. Jpn J Clin Ophthalmol 1971; 25: 607.
^ Muthiah MN, Michaelides M, Child CS, Mitchell SM (2007). "Acute retinal necrosis: a national population‐based study to assess the incidence, methods of diagnosis, treatment strategies and outcomes in the UK". Br J Ophthalmol 91 (11): 1452–5. doi:10.1136/bjo.2007.114884. PMC 2095441. PMID 17504853.
^ Lau CH, Missotten T, Salzmann J, Lightman SL (2007). "Acute retinal necrosis features, management, and outcomes". Ophthalmology 114 (4): 756–62. doi:10.1016/j.ophtha.2006.08.037. PMID 17184841.
^ Kezuka T, Atherton SS (2007). "Acute retinal necrosis". Chem Immunol Allergy. Chemical Immunology and Allergy 92: 244–53. doi:10.1159/000099275. ISBN 3-8055-8187-4. PMID 17264500.
^ King J, Chung M, DiLoreto DA (2007). "A 9 year-old girl with herpes simplex virus type 2 acute retinal necrosis treated with intravitreal foscarnet". Ocul. Immunol. Inflamm. 15 (5): 395–8. doi:10.1080/09273940701486431. PMID 17972224.
^ Emerson GG, Smith JR, Wilson DJ, Rosenbaum JT, Flaxel CJ (2006). "Primary treatment of acute retinal necrosis with oral antiviral therapy". Ophthalmology 113 (12): 2259–61. doi:10.1016/j.ophtha.2006.05.063. PMID 16996614.

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1. 水痘帯状疱疹ウイルス感染症の臨床症状：帯状疱疹 clinical manifestations of varicella zoster virus infection herpes zoster
2. 全身性疾患および感染に関連した網膜血管炎 retinal vasculitis associated with systemic disorders and infections
3. 単純ヘルペスウイルス1型感染の臨床症状および診断 clinical manifestations and diagnosis of herpes simplex virus type 1 infection
4. 免疫正常患者における帯状疱疹の治療 treatment of herpes zoster in the immunocompetent host
5. ブドウ膜炎：病因、臨床症状、および診断 uveitis etiology clinical manifestations and diagnosis

Witmer MT, Pavan PR, Fouraker BD, Levy-Clarke GA.SourceDepartment of Ophthalmology, College of Medicine, University of South Florida, Tampa, Florida, USA St. Luke's Cataract and Laser Institute, Tarpon Springs, Florida, USA.
Acta ophthalmologica.Acta Ophthalmol.2011 Nov;89(7):599-607. doi: 10.1111/j.1755-3768.2010.01911.x. Epub 2010 Jul 20.
Acute retinal necrosis (ARN) syndrome is characterized by severe intraocular inflammation, occlusive vasculopathy and peripheral retinal necrosis. Vision threatening complications of this syndrome include retinal detachment, macular oedema and ischaemia and optic neuropathy. Optic nerve involvement
PMID 20645925

Evereklioglu C.SourceDivision of Uvea-Behçet Unit, Department of Ophthalmology, Erciyes University Medical Faculty, Kayseri, Turkey.
Current opinion in ophthalmology.Curr Opin Ophthalmol.2011 Nov;22(6):508-16.
PURPOSE OF REVIEW: To alert physician to timely recognition and current treatment of recurrent hypopyon iridocyclitis or panuveitis in ocular Behçet disease (OBD).RECENT FINDINGS: Interferon-α, rituximab, intravitreal triamcinolone, and biological response modifiers by tumor necrosis factor inhibi
PMID 21897239