WordNet

be a contributing factor; "make things factor into a companys profitability"
any of the numbers (or symbols) that form a product when multiplied together
an independent variable in statistics
anything that contributes causally to a result; "a number of factors determined the outcome"
consider as relevant when making a decision; "You must factor in the recent developments" (同)factor in, factor out
resolve into factors; "a quantum computer can factor the number 15" (同)factor in, factor out
an event known to have happened or something known to have existed; "your fears have no basis in fact"; "how much of the story is fact and how much fiction is hard to tell"
a concept whose truth can be proved; "scientific hypotheses are not facts"
a piece of information about circumstances that exist or events that have occurred; "first you must collect all the facts of the case"
a statement or assertion of verified information about something that is the case or has happened; "he supported his argument with an impressive array of facts"
any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
(biology) any agency bringing about activation; a molecule that increases the activity of an enzyme or a protein that increases the production of a gene product in DNA transcription

PrepTutorEJDIC

(…の)『要因』,(…を生み出す)要素《+『in』+『名』(do『ing』)》 / 囲数,約数 / 代理人,《おもに英》仲買人 / =factorize
〈C〉『事実』,実際にある(あった)事 / 〈U〉真相,真実(truth) / 《the~》(法律用語で)犯行
蛋白(たんばく)質

UpToDate Contents

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1. T細胞受容体シグナル伝達 t cell receptor signaling
2. 喘息における吸入ステロイドの分子学的影響 molecular effects of inhaled glucocorticoid therapy in asthma
3. 免疫系に対するステロイドの影響 glucocorticoid effects on the immune system
4. 糸球体半月体形成の機序 mechanisms of glomerular crescent formation
5. 2型糖尿病の病因 pathogenesis of type 2 diabetes mellitus

English Journal

Activating Transcription Factor 3 Is Essential for Cigarette Smoke-Induced Mucin Expression via Interaction with Activator Protein-1.

Wu YP1, Wu YF1, Zhang C1, Zhou HB1, Cao C1, Li M1, Zhu C1, Ying SM1, Chen ZH2, Shen HH3, Li W4.
The American journal of pathology.Am J Pathol.2017 Feb;187(2):280-291. doi: 10.1016/j.ajpath.2016.10.012. Epub 2016 Nov 29.
Mucus hypersecretion is an important pathologic feature of chronic obstructive pulmonary disease. Activating transcription factor 3 (ATF3) is an adaptive-response gene that participates in various cellular processes. However, little is known about its role in cigarette smoke (CS)-induced mucus hyper
PMID 27912076

Inhibition of BATF/JUN transcriptional activity protects against osteoarthritic cartilage destruction.

Rhee J1, Park SH1, Kim SK1, Kim JH1,2, Ha CW3,4, Chun CH5, Chun JS1.
Annals of the rheumatic diseases.Ann Rheum Dis.2017 Feb;76(2):427-434. doi: 10.1136/annrheumdis-2015-208953. Epub 2016 May 4.
OBJECTIVE: The basic leucine zipper transcription factor, ATF-like (BATF), a member of the Activator protein-1 family, promotes transcriptional activation or repression, depending on the interacting partners (JUN-B or C-JUN). Here, we investigated whether the BATF/JUN complex exerts regulatory effec
PMID 27147707

Cigarette smoke extract induces epithelial-mesenchymal transition of human bladder cancer T24 cells through activation of ERK1/2 pathway.

Sun X1, Deng Q2, Liang Z3, Liu Z1, Geng H1, Zhao L1, Zhou Q4, Liu J1, Ma J1, Wang D1, Yu D5, Zhong C6.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.Biomed Pharmacother.2017 Feb;86:457-465. doi: 10.1016/j.biopha.2016.12.022. Epub 2016 Dec 23.
Bladder cancer is a common genitourinary malignant disease worldwide. Abundant evidence has shown that cigarette smoke (CS) is a crucial risk factor for bladder cancer. Nevertheless, the mechanism underlying the relationship between cigarette smoking and bladder cancer remains unclear. In the presen
PMID 28012925