activation-induced cytidine deaminase gene

AID遺伝子

WordNet

1. reason or establish by induction
2. cause to arise; "induce a crisis" (同)bring_on
3. produce electric current by electrostatic or magnetic processes (同)induct
4. cause to do; cause to act in a specified manner; "The ads induced me to buy a VCR"; "My children finally got me to buy a computer"; "My wife made me buy a new sofa" (同)stimulate, cause, have, get, make
5. cause to occur rapidly; "the infection precipitated a high fever and allergic reactions" (同)stimulate, rush, hasten
6. making active and effective (as a bomb)
7. stimulation of activity in an organism or chemical
8. (genetics) a segment of DNA that is involved in producing a polypeptide chain; it can include regions preceding and following the coding DNA as well as introns between the exons; it is considered a unit of heredity; "genes were formerly called factors" (同)cistron, factor
9. brought about or caused; not spontaneous; "a case of steroid-induced weakness"
10. informal term for information; "give me the gen on your new line of computers"

PrepTutorEJDIC

1. 〈人〉‘に'『勧めて』(…)『させる』 / …‘を'『引き起こす』,もたらす(cause) / 〈電気〉‘を'誘導する / …‘を'帰納する
2. 活動化 / (物質の)活性化(化学反応を起こしやすくすること)
3. 遺伝子

UpToDate Contents

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• 1. 高IgM症候群 hyperimmunoglobulin m syndromes
• 2. Hypertrophic cardiomyopathy: Gene mutations and clinical genetic testing
• 3. びまん性大細胞型B細胞性リンパ腫および原発性縦隔大細胞型B細胞リンパ腫の病理学 pathobiology of diffuse large b cell lymphoma and primary mediastinal large b cell lymphoma
• 4. BおよびTリンパ球の正常な発生 normal b and t lymphocyte development
• 5. サラセミア症候群の分子病理 molecular pathology of the thalassemic syndromes

English Journal

• Efficient AID targeting of switch regions is not sufficient for optimal class switch recombination.

• Bonaud A1, Lechouane F1, Le Noir S1, Monestier O1, Cogné M2, Sirac C1.
• Nature communications.Nat Commun.2015 Jul 6;6:7613. doi: 10.1038/ncomms8613.
• Antibody affinity maturation relies on activation-induced cytidine deaminase (AID)-dependent somatic hypermutation (SHM) of immunoglobulin (Ig) loci. Class switch recombination (CSR) can in parallel occur between AID-targeted, transcribed, spliced and repetitive switch (S) regions. AID thus initiate
• PMID 26146363

• Emerging understanding of Bcl-2 biology: Implications for neoplastic progression and treatment.

• Correia C1, Lee SH1, Meng XW1, Vincelette ND2, Knorr KL2, Ding H3, Nowakowski GS4, Dai H5, Kaufmann SH6.
• Biochimica et biophysica acta.Biochim Biophys Acta.2015 Jul;1853(7):1658-1671. doi: 10.1016/j.bbamcr.2015.03.012. Epub 2015 Mar 27.
• Bcl-2, the founding member of a family of apoptotic regulators, was initially identified as the protein product of a gene that is translocated and overexpressed in greater than 85% of follicular lymphomas (FLs). Thirty years later we now understand that anti-apoptotic Bcl-2 family members modulate t
• PMID 25827952

• Activation-induced cytidine deaminase contributes to pancreatic tumorigenesis by inducing tumor-related gene mutations.

• Sawai Y1, Kodama Y2, Shimizu T1, Ota Y1, Maruno T1, Eso Y1, Kurita A1, Shiokawa M1, Tsuji Y1, Uza N1, Matsumoto Y1, Masui T3, Uemoto S3, Marusawa H1, Chiba T1.
• Cancer research.Cancer Res.2015 Jun 25. pii: canres.3028.2014. [Epub ahead of print]
• Pancreatic ductal adenocarcinoma (PDA) develops via an accumulation of various gene mutations. The mechanism underlying the mutations in PDA development, however, is not fully understood. Recent insight into the close association between the mutation pattern of various cancers and specific mutagens
• PMID 26113087

Japanese Journal

• 免疫グロブリンの体細胞高頻度突然変異とserine/arginine-rich protein splicing factor (SRSF) (特集 免疫グロブリンの体細胞高頻度突然変異とクラススイッチ)

• 臨床免疫・アレルギー科 61(5), 489-495, 2014-05
• NAID 40020104323

• AIDによる免疫グロブリンの体細胞高頻度突然変異誘導と関連分子 (特集 免疫グロブリンの体細胞高頻度突然変異とクラススイッチ)

• 臨床免疫・アレルギー科 61(5), 467-471, 2014-05
• NAID 40020104257

• C-terminal region of activation-induced cytidine deaminase (AID) is required for efficient class switch recombination and gene conversion.

• Proceedings of the National Academy of Sciences of the United States of America 111(6), 2253-2258, 2014-02-11
• NAID 120005395696

Related Links

• AICDA activation induced cytidine deaminase [ (human)]

This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin ...

• Aicda activation-induced cytidine deaminase [ (house mouse)]

Gene provides a unified query environment for genes defined by sequence and/or in NCBI's Map Viewer. ... Gene ID: 11628, updated on 14-Aug-2016 Summary Other designations activation induced deaminase, cytidine ...

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★リンクテーブル★

リンク元	「AID遺伝子」
関連記事	「induce」「induced」「activation」「deaminase」

「AID遺伝子」

　　[★]

同

AID gene, activation-induced cytidine deaminase gene

「induce」

　　[★]

• v.

• 誘発する、誘導する、誘起する、導入する、引き起こす

関

cause、challenge、derivation、elicit、elicitation、evocation、evoke、guidance、induction、inductive、introduce、introduction、precipitate、provocation、provoke、spark

　 　 　 　 　 　

「induced」

　　[★]

• v.

• (induceの過去分詞)誘導される、引き起こされる

hypercalcaemia induced pancreatitis 高カルシウム血症による膵炎

　

「activation」

　　[★]

• 活性化、賦活化、賦活

関

activate、activated、turn on

　 　 　

「deaminase」

　　[★]

デアミナーゼ、脱アミノ酵素