acetyldigitoxin

Acetyldigitoxin
Systematic (IUPAC) name
	[(2R,3R,4S,6S)-3-Hydroxy-6-[(2R,4S,6S)-4-hydroxy-6-[(2R,3S,4S,6R)-4-hydroxy-6-[ [(5R,8R,9S,10S,13R,14S,17R')-14-hydroxy-10,13-dimethyl-17-(5-oxo-2H-furan-3-yl)-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-yl]oxy]-2-methyloxan-3-yl]oxy-2-methyloxan-3-yl]oxy-2-methyloxan-4-yl] acetate
Identifiers
CASRN	1111-39-3
ATC code	C01AA01 (WHO)
PubChem	CID 68949
DrugBank	DB00511
ChemSpider	4447572
UNII	0ZV4Q4L2FU
KEGG	D06881
ChEBI	CHEBI:53773
ChEMBL	CHEMBL1200634
Chemical data
Formula	C43H66O14
Molar mass	806.976 g/mol
	SMILES O=C\1OC/C(=C/1)[C@H]2CC[C@@]8(O)[C@]2(C)CC[C@H]7[C@H]8CC[C@H]6[C@]7(C)CC[C@H](O[C@@H]5O[C@@H]([C@@H](O[C@@H]4O[C@@H]([C@@H](O[C@@H]3O[C@H](C)[C@@H](O)[C@@H](OC(=O)C)C3)[C@@H](O)C4)C)[C@@H](O)C5)C)C6 ;
	InChI InChI=1S/C43H66O14/c1-21-38(48)33(54-24(4)44)19-37(51-21)57-40-23(3)53-36(18-32(40)46)56-39-22(2)52-35(17-31(39)45)55-27-9-12-41(5)26(16-27)7-8-30-29(41)10-13-42(6)28(11-14-43(30,42)49)25-15-34(47)50-20-25/h15,21-23,26-33,35-40,45-46,48-49H,7-14,16-20H2,1-6H3/t21-,22-,23-,26-,27+,28-,29+,30-,31+,32+,33+,35+,36+,37+,38-,39-,40-,41+,42-,43+/m1/s1 ; Key:HPMZBILYSWLILX-UMDUKNJSSA-N ;
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Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/05/27 16:47:50」(JST)

Acetyldigitoxin is a cardiac glycoside. It is an acetyl derivative of digitoxin.

This drug article relating to the cardiovascular system is a stub. You can help Wikipedia by expanding it.

Coleman JJ1, Ghosh S, Okoli I, Mylonakis E.
PloS one.PLoS One.2011;6(9):e25321. doi: 10.1371/journal.pone.0025321. Epub 2011 Sep 22.
Secondary metabolites are well known for their ability to impede other microorganisms. Reanalysis of a screen of natural products using the Caenorhabditis elegans-Candida albicans infection model identified twelve microbial secondary metabolites capable of conferring an increase in survival to infec
PMID 21966496

Characterization of minor site probes for human serum albumin by high-performance affinity chromatography.

Sengupta A1, Hage DS.
Analytical chemistry.Anal Chem.1999 Sep 1;71(17):3821-7.
This study used high-performance affinity chromatography (HPAC) and immobilized human serum albumin (HSA) columns to examine the specificity and cross-reactivity of various compounds that have been proposed as markers for the minor binding sites of HSA. These agents included acetyldigitoxin and digi
PMID 10489529

Characterisation of the binding of digitoxin and acetyldigitoxin to human serum albumin by high-performance affinity chromatography.

Hage DS1, Sengupta A.
Journal of chromatography. B, Biomedical sciences and applications.J Chromatogr B Biomed Sci Appl.1999 Mar 5;724(1):91-100.
Zonal elution and high-performance affinity chromatography were used to examine interactions of the drugs digitoxin and acetyldigitoxin with the protein human serum albumin (HSA). This was done by injecting small amounts of digitoxin and acetyldigitoxin onto an immobilized HSA column in the presence
PMID 10202961

Characterisation of the binding of digitoxin and acetyldigitoxin to human serum albumin by high-performance affinity chromatography

HAGE David S.,SENGUPTA Arundhati
Journal of chromatography. B, Biomedical sciences and applications 724(1), 91-100, 1999-03-05
NAID 10024534630

High-performance liquid chromatography-ionspray mass spectrometry for the specific determination of digoxin and some related cardiac glycosides in human plasma

TRACQUI A.,KINTZ P.,LUDES B.,MANGIN P.
Journal of chromatography. B, Biomedical sciences and applications 692(1), 101-109, 1997-04-25
NAID 10024514196

Studies on the Constituents of Digitalis purpurea L. XXIV. On the Structures of Purlanosides-A and -B.

傍士和彦
Chemical & pharmaceutical bulletin 9(7), 566-571, 1961-07-25
… Further, it was determined that the acetyl groups of acetyldigitoxin-γ and acetyl-gitoxin-γ are in the first digitoxose. …
NAID 110003618674